99 Results for "

complement factor

" in MedChemExpress (MCE) Product Catalog:
Products (99)

99 Results for "complement factor" in MCE Product Catalog:

Cat. No.: HY-147604
CAS No.: 2760669-72-3
Target:  

Complement System

Domaines de recherche:  

Inflammation/Immunology

Factor B-IN-2 (Example 1 target compound) is a potent complement factor B inhibitor, with an IC50 of 1.5 μM. Factor B-IN-2 can be used for the research of diseases related to inflammation and immunity .
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Cat. No.: HY-P990955
CAS No.: 2839652-75-2
Synonyms: ADX-097

Target:  

CD3 Complement System

Domaines de recherche:  

Inflammation/Immunology

Ebribafusp alfa (ADX-097) comprising a humanized anti-C3d monoclonal antibody linked to two moieties of the first five consensus repeats of factor H (fH1-5). Ebribafusp alfa binds C3d and related fragments, catalyzes AP convertase dissociation, acts as a factor I co-factor for C3b cleavage, and delivers fH1-5 moieties to C3d-deposited tissues for local complement inhibition without systemic blockade. Ebribafusp alfa reduces glomerular C3 deposition, proteinuria, urine albumin-creatinine ratios, and urine soluble C5b-9 levels, preserves podocyte foot-process architecture, inhibits skin complement activation, and localizes to UVB-damaged primate skin. Ebribafusp alfa can be used for the research of membranous nephropathy, bullous pemphigoid, discoid lupus erythematosus, C3 glomerulopathy, IgA nephropathy, and lupus nephritis .
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Cat. No.: HY-P990377

Target:  

Inhibitory Antibodies

Domaines de recherche:  

Inflammation/Immunology

Anti-Complement Factor B Antibody is a CHO-expressed human antibody that targets Complement Factor B. The Anti-Complement Factor B Antibody carries a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Complement Factor B Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-102034R
CAS No.: 1386455-76-0
Domaines de recherche:  

Inflammation/Immunology

Complement factor D-IN-1 (Standard) is the analytical standard of Complement factor D-IN-1 (HY-102034). This product is intended for research and analytical applications. Complement factor D-IN-1 is a potent and selective small-molecule reversible factor d inhibitor, with IC50s of 0.006 and 0.05 μM in FD Thioesterolytic Fluorescent Assay and a MAC Deposition Assay, respectively.
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Cat. No.: HY-P992456
Target:  

Complement System

Domaines de recherche:  

Cardiovascular Disease Endocrinology

SAR-443809 is a monoclonal antibody targeting complement factor Bb that inhibits the alternative complement pathway. SAR-443809 blocks the cleavage of C3 and factor B via selective binding to the activated form factor Bb, with a KD of 7.3 nM for human factor Bb. SAR-443809 inhibits the amplification loop of the alternative complement pathway and C3 activation, reduces C3b deposition, and blocks the activation of pathways associated with intravascular and extravascular hemolysis. SAR-443809 can be used for research on hematological and renal disorders mediated by abnormal alternative complement pathway activity .
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Cat. No.: HY-P7861
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFD; C3 Convertase Activator; Prev. PFD; D Component Of complement (Adipsin); Prev. DF; complement factor D Preproprotein; Properdin factor D; complement factor D (Adipsin); Adipsin; complement factor D; ADN
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7876
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFD; C3 Convertase Activator; Prev. PFD; D Component Of complement (Adipsin); Prev. DF; complement factor D Preproprotein; Properdin factor D; complement factor D (Adipsin); Adipsin; complement factor D; ADN
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P71726
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFD; C3 Convertase Activator; Prev. PFD; D Component Of complement (Adipsin); Prev. DF; complement factor D Preproprotein; Properdin factor D; complement factor D (Adipsin); Adipsin; complement factor D; ADN
Species:  
Rat
Source:  
P. pastoris
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Cat. No.: HY-P78273
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CFD; C3 Convertase Activator; Prev. PFD; D Component Of complement (Adipsin); Prev. DF; complement factor D Preproprotein; Properdin factor D; complement factor D (Adipsin); Adipsin; complement factor D; ADN
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78545
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CFD; C3 Convertase Activator; Prev. PFD; D Component Of complement (Adipsin); Prev. DF; complement factor D Preproprotein; Properdin factor D; complement factor D (Adipsin); Adipsin; complement factor D; ADN
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7861A
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFD; C3 Convertase Activator; Prev. PFD; D Component Of complement (Adipsin); Prev. DF; complement factor D Preproprotein; Properdin factor D; complement factor D (Adipsin); Adipsin; complement factor D; ADN
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77898
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CFD; C3 Convertase Activator; Prev. PFD; D Component Of complement (Adipsin); Prev. DF; complement factor D Preproprotein; Properdin factor D; complement factor D (Adipsin); Adipsin; complement factor D; ADN
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P704331
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFD; C3 Convertase Activator; Prev. PFD; D Component Of complement (Adipsin); Prev. DF; complement factor D Preproprotein; Properdin factor D; complement factor D (Adipsin); Adipsin; complement factor D; ADN
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P704214
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CFP; complement factor Properdin, Isoform CRA_c; Prev. PFC; Alternative Protein CFP; complement factor P; PROPERDIN; Properdin P factor, complement; BFD; Properdin; PFD; CDNA FLJ16673 Fis, Clone THYMU3003403, Highly Similar To Properdin; complement factor
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705409
Pureté:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CFP; complement factor Properdin, Isoform CRA_c; Prev. PFC; Alternative Protein CFP; complement factor P; PROPERDIN; Properdin P factor, complement; BFD; Properdin; PFD; CDNA FLJ16673 Fis, Clone THYMU3003403, Highly Similar To Properdin; complement factor
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P83239
Synonyms: C3/C5 convertase; complement factor B; PBF2; Properdin factor B

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P810367
Synonyms: C3/C5 convertase, complement factor B, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Rat

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Cat. No.: HY-P703770
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.;≥ 90%, as determined by HPLC.
Synonyms: CFI; C3bINA; Prev. IF; complement factor I Heavy Chain; C3B/C4B Inactivator; Light Chain Of factor I; C3b-INA; complement Component I; KAF; I factor (complement); FI; CFI Protein; Konglutinogen-Activating factor; ARMD13; C3b-Inactivator; AHUS3; complement
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P703793
Pureté:  ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: CFI; C3bINA; Prev. IF; complement factor I Heavy Chain; C3B/C4B Inactivator; Light Chain Of factor I; C3b-INA; complement Component I; KAF; I factor (complement); FI; CFI Protein; Konglutinogen-Activating factor; ARMD13; C3b-Inactivator; AHUS3; complement
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70031
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CFHR2; H factor-Like Protein 2; Prev. CFHL2; DDESK59; Prev. HFL3; FHR-2; FHR2; complement factor H-Related 2; complement factor H-Related Protein 2; factor H-Related Gene 2; H factor (complement)-Like 3; complement factor H Related 2; H factor-Like 3
Species:  
Human
Source:  
HEK293
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