122 Results for "

thyroid cells

" in MedChemExpress (MCE) Product Catalog:
Products (122)

122 Results for "thyroid cells" in MCE Product Catalog:

Cat. No.: HY-101246
CAS No.: 269730-03-2
Purity:  99.29%
Target:  

RET

Research Areas:  

Cancer

RPI-1 is a specific, orally available 2-indolinone Ret tyrosine kinase inhibitor. RPI-1 inhibits proliferation, Ret tyrosine phosphorylation, Ret protein expression, and the activation of PLCgamma, ERKs and AKT in human medullary thyroid carcinoma TT cells. Antitumor activity .
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Cat. No.: HY-150526
CAS No.: 2708237-76-5
EGCG-4″-sulfate is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate sulfate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. EGCG-4″-sulfate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .
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Cat. No.: HY-Y1097
CAS No.: 4376-18-5
Synonyms: 2-(Methoxycarbonyl)benzoic acid
Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats .
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Cat. No.: HY-13653S1
Synonyms: EGCG-d4; Epigallocatechol Gallate-d4
(-)-Epigallocatechin Gallate-d4 (EGCG-d4) is the deuterium labeled (-)-Epigallocatechin Gallate (HY-13653). (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .
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Cat. No.: HY-149132
CAS No.: 1191043-85-2
Purity:  96.7%
Synonyms: DDA
Dendrogenin A (DDA) is a ligand for liver X receptor (LXR), that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor, thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC50 of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase .
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Cat. No.: HY-Q04764
CAS No.: 1005178-02-8
Research Areas:  

Cancer

TI17 is an inhibitor of the thyroid hormone receptor-interacting protein Trip13 and has anticancer activity. TI17 effectively inhibits multiple myeloma (MM) cell proliferation and induces cell cycle arrest and apoptosis. Trip13 is an AAA-ATPase that mediates double-strand break (DSB) repair; TI17 inhibits Trip13 function and increases DNA damage .
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Cat. No.: HY-B0035S
CAS No.: 1020719-82-7
Synonyms: Sulfadimidine-d4; Sulfadimerazine-d4
Sulfamethazine-d4 (Sulfadimidine-d4) is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections .
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Cat. No.: HY-B0035S2
CAS No.: 77643-91-5
Synonyms: Sulfadimidine-13C6; Sulfadimerazine-13C6
Sulfamethazine- 13C6 is a 13C-labeled Sulfamethazine (HY-A0178). Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections .
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Cat. No.: HY-17518
CAS No.: 283159-90-0
Synonyms: IR5885; Valiphenal
Research Areas:  

Infection

Valifenalate (IR5885; Valiphenal) is an insecticide agent and fungicide, which is approved for application on high-value crops such as grapes, tomatoes and other vegetables. Valifenalate interferes with cell-wall synthesisValifenalate is effective against various types of mildew. Valifenalate can be used against crown rot of rose cuased by Phytophthora citrophthora. Valifenalate induces non-adverse thyroid changes via adaptive induction of uridine 5’-diphosphoglucuronosyltransferase (UGT) in the liver of dogs and rats .
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Cat. No.: HY-149380
CAS No.: 3057544-65-4
Target:  

Raf

Research Areas:  

Cancer

Vem-L-Cy5 (compound 3),modified with the NIR fluorophore cyanine-5 (Cy5),is a Vemurafenib (HY-12057)-based inhibitor of BRAF. Vem-L-Cy5 targets to BRAF V600E,and also inhibits MEK phosphorylation. Vem-L-Cy5 has cell permeability,and inhibits cell growth of many types of cancer .
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Cat. No.: HY-P99712
CAS No.: 2362015-67-4
Synonyms: hz208F2-4

Research Areas:  

Cancer

Lonigutamab (hz208F2-4) is a humanized anti-IGF-1R monoclonal antibody, serveing as a targeting vector for antibody-drug conjugates (ADCs). Lonigutamab causes G2-M phase cell cycle arrest and increases apoptosis in IGF-1R-overexpressing tumor cells. Lonigutamab demonstrates potent antitumor efficacy in IGF-1R-overexpressing xenograft models. Lonigutamab can be used for the study of Solid tumors with overexpression of IGF-1R and thyroid eye diseases .
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Cat. No.: HY-129046E
CAS No.: 9001-99-4
Synonyms: Ribonuclease A DNase & Protease Free, Recombinant
Research Areas:  

Endocrinology Cancer

RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase A (DNase & Protease Free), Recombinant is recombinant RNase A, which does not contain DNase and protease .
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Cat. No.: HY-129046B
CAS No.: 9001-99-4
Synonyms: Ribonuclease A DNase & Protease Free
Research Areas:  

Others Endocrinology Cancer

RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase A, Bovine Pancreas (DNase & Protease Free) is RNase A derived from bovine pancreas and does not contain DNase or protease .
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Cat. No.: HY-P9972
CAS No.: 1935694-88-4
Synonyms: PDR001

Target:  

PD-1/PD-L1 IFNAR

Research Areas:  

Cancer

Spartalizumab is a humanized PD-1 IgG4 monoclonal antibody, with a Kd of 0.83 nM for human PD-1 and a Kd of 0.93 nM for cynomolgus monkey PD-1. Spartalizumab binds to PD-1 and blocks its interaction with the ligands PD-L1 and PD-L2. Spartalizumab induces increased IFNγ release. Spartalizumab can be used in the research of anaplastic thyroid carcinoma (ATC) and neuroendocrine neoplasms (NENs) .
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Cat. No.: HY-P3689
CAS No.: 198277-54-2
Research Areas:  

Others

[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system .
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Cat. No.: HY-105552
CAS No.: 123-47-7
Synonyms: Endoiodin
Research Areas:  

Others

Prolonium (iodide) is membrane impermeant. Prolonium (iodide) can easily penetrate dead or damaged cells. Prolonium (iodide) is a probe that can be used for fluorescence microscopy and flow cytometry . Prolonium (iodide) also serve as an iodine source to maintain thyroid function .
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Cat. No.: HY-B0035B
CAS No.: 57-68-1
Synonyms: Sulfadimidine 100 µg/mL in acetonitrile; Sulfadimerazine 100 µg/mL in acetonitrile
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Sulfamethazine (Sulfadimidine) 100 µg/mL in acetonitrile is a brain-penetrant sulfonamide antibiotic. Sulfamethazine 100 µg/mL in acetonitrile inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine 100 µg/mL in acetonitrile can be used for research on bacterial infections .
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Cat. No.: HY-14823G
CAS No.: 211110-63-3
Synonyms: GC-1 (GMP); QRX-431 (GMP)
Sobetirome (GMP) is Sobetirome (HY-14823) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Sobetirome (GC-1) is a thyroid hormone receptor β (TRβ)-specific agonist which bind selectively to TRβ-1 with an EC50 of 0.16 μM .
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Cat. No.: HY-129046H
CAS No.: 9001-99-4
Research Areas:  

Endocrinology Cancer

RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase A, Recombinant (Protease & DNase free, animal free) is recombinant RNase A that does not contain protease and DNase and does not contain animal components .
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Cat. No.: HY-148745
CAS No.: 2241517-83-7
Target:  

Drug Derivative HSP

Research Areas:  

Cancer

JG-258 is an inactive negative control for Hsp70 inhibitors. JG-258 is an inactive structural analog of JG-98 (HY-117282), an allosteric inhibitor of heat shock protein 70 (Hsp70) with demonstrated anticancer activity. JG-258 can be used in cancer-related research .
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