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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
735 Results for "
beta2
" in MedChemExpress (MCE) Product Catalog:
Products (735)
735 Results for "beta2" in MCE Product Catalog:
Cat. No.: HY-W751275
CAS No.: 1415400-49-5
Cat. No.: HY-W751276
CAS No.: 1415400-62-2
Cat. No.: HY-P701002
Synonyms: HLAG; HLA-6.0; HLA-G; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; MHC class I antigen G; HLA G antigen; HLA class I histocompatibility antigen, alpha chain G; HDCMA22P; CDABP0092; B2M; beta-2-microglobulin form pI 5.3
Species:
Human
Source:
HEK293
Synonyms: YN968D1-d8 free base
Cat. No.: HY-B1421S2
CAS No.: 1219794-72-5
Synonyms: LY031537-d3
Cat. No.: HY-NP144
CAS No.: 93928-24-6
Cat. No.: HY-P76144
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PRKAG1; 5'-AMP-Activated Protein Kinase, Gamma-1 Subunit; Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1; AMPK Subunit Gamma-1; 5'-AMP-Activated Protein Kinase Subunit Gamma-1; AMPK Gamma-1 Chain; Protein Kinase, AMP-Activated, Gamma 1 Non-Cat
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P811763
Synonyms: ADTB2, CLAPB1, AP2B1, AP-2 complex subunit beta, AP105B, Adaptor protein complex AP-2 subunit beta, Adaptor-related protein complex 2 subunit beta, beta-2-adaptin, beta-adaptin, Clathrin assembly protein complex 2 beta large chain, Plasma membrane adaptor HA2/AP2 adaptin beta subunit
Cat. No.: HY-P811763A
Synonyms: ADTB2, CLAPB1, AP2B1, AP-2 complex subunit beta, AP105B, Adaptor protein complex AP-2 subunit beta, Adaptor-related protein complex 2 subunit beta, beta-2-adaptin, beta-adaptin, Clathrin assembly protein complex 2 beta large chain, Plasma membrane adaptor HA2/AP2 adaptin beta subunit
Cat. No.: HY-130349
CAS No.: 121124-29-6
Synonyms: L-656,748
Target:
Research Areas:
Emamectin B1a (L-656,748) is a semisynthetic derivative of avermectin B1a that binds to GABA receptors (Ki=17.6 nM in rat brain membranes) and enhances GABA responses. Emamectin B1a acitivates GABAA receptors α1β1γ2, α1β2γ2, and α1β3γ2 with IC50s of 57, 210, and 49.8 nM, respectively. Emamectin B1a also binds to glycine receptors, inhibiting glycine receptors with an IC50=218 nM in rat spinal cord. Emamectin B1a (1.067 ng/mL) caused 90% mortality of S. exigua larvae in foliar spray bioassays and topical application, making it more toxic than avermectin B1.
Cat. No.: HY-187204
Target:
Research Areas:
RX-044 is a ROCK1/ROCK2 inhibitor with ROCK1 IC50 10.01 nM and ROCK2 IC50 9.68 nM, and demonstrates kinase selectivity. RX-044 induces reversible cell retraction, modulates cytoskeletal organization via F-actin depolymerization, inhibits cell contractility, and attenuates TGF-β2-induced cell migration. RX-044 preserves retinal ganglion cell survival, restores electroretinography responses, and ameliorates histopathological changes. RX-044 lowers intraocular pressure in a mouse ocular hypertension model. RX-044 shows no cytotoxicity in target cells. RX-044 exhibits initial ocular irritation that subsides with extended dosing. RX-044 can be used for the research of glaucoma .
Cat. No.: HY-46286
CAS No.: 352560-76-0
Synonyms: N-(4-tert-butyl-1,3-thiazol-2-yl)-3-fluorobenzamide
Research Areas:
TTFB (N-(4-tert-butyl-1,3-thiazol-2-yl)-3-fluorobenzamide) is a selective, non-competitive zinc-activated channel (ZAC) antagonist. TTFB inhibits Zn 2+- and H +-induced ZAC currents with IC50 values of 3 μM and 8.5 μM, respectively, and has an IC50 of 4.7 μM against spontaneous activity. TTFB shows no significant agonistic, antagonistic or modulatory activity towards representative classical Cys-loop receptors including m5-HT3AR, hα3β4 nAChR, hα1β2γ2S GABAAR and hα1 GlyR. TTFB can be used to investigate the physiological and pathological functions of ZAC.
Cat. No.: HY-E70305
CAS No.: 84012-69-1
Target:
Research Areas:
GlcNAc-1-Phosphotransferase is a Golgi membrane-bound glycosylphosphotransferase. GlcNAc-1-Phosphotransferase is composed of an α/β catalytic subunit encoded by the GNPTAB gene and a γ regulatory subunit encoded by the GNPTG gene, forming an α2β2γ2 hexameric complex. GlcNAc-1-Phosphotransferase catalyzes the transfer of GlcNAc-1-phosphate from UDP-GlcNAc to the C-6 hydroxyl group of terminal mannose residues on high-mannose-type N-glycans, thereby initiating the mannose-6-phosphate tagging pathway. GlcNAc-1-Phosphotransferase loss-of-function mutations can lead to lysosomal storage diseases such as mucolipidosis type II/III. GlcNAc-1-Phosphotransferase can be used in research related to mucolipidosis [2] .
Cat. No.: HY-171807
CAS No.: 189274-78-0
Research Areas:
TC-2559 free base is a α4β2 nicotinic acetylcholine receptor (nAChR) agonists with an EC50 of 0.18 μM. TC-2559 free base shows much weaker potencies on the group of b4-containing nAChR subtypes, α2β4, α4β4 and α3β4 receptors, with EC50s in the range of 10-30 µM. TC-2559 free base can increase the discharge of dopamine cells in the ventral tegmental area (VTA) of rats in vitro, enhancing the excitability and aggressive behavior of VTA dopamine neurons. TC-2559 free base inhibits STAT3 to exert anti-inflammatory properties and relieves mice mechanical allodynia and improve rats cognitive deficits. TC-2559 free base can be used for the study of nerve pain [2] .
Cat. No.: HY-P705359
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HLA-A; MHC Class 1 Antigen; Major Histocompatibility Complex, Class I, A; MHC ClassI Antigen; HLA Class I Histocompatibility Antigen, A Alpha Chain; Lymphocyte Antigen; MHC Class I Antigen HLA-A Heavy Chain; HLA-A*6602 Antigen; Leukocyte Antigen Class I-A; HLA-Aw34.2 Antigen; HLAA; HLA-A-6802 Protein; Major Histocompatibility Complex Class I HLA-A-32 Protein; HLA-A-0203 Protein; HLA Class I Histocompatibility Antigen, A-1 Alpha Chain; MHC Class1 Antigen; HLA Class I Histocompatibility Antigen A Alpha Chain; Leukocyte Antigen; Signal Peptide Alpha1 And Alpha2 Domain; HLA-A26.4 Antigen; HLA Class I Histocompatibility Antigen; HLA-A10SA Antigen; MHC HLA-A Cell Surface Glycoprotein; MHC Class I HLA-A; HLA Class I A Locus Antigen A*68new; HLA-A26.3 Antigen; MHC Class I Human Leukocyte Antigen; HLA-A30.2 Antigen; Ig-Like Domain-Containing Protein; HLA-A2new Protein; MHC Class I Antigen Null Protein; Leucocyte Antigen; HLA-A Alpha1 And Alpha2 Domains; HLA-A9HH Antigen; MHC Class I Antigen Heavy Chain; MHC Class I Anti; Leucocyte Antigen A Alpha Chain; HLA-A29 Variant; Truncated MHC Class I Antigen; HLA-A25 Protein; Truncated MHC Class I Protein; MHC Alpha Chain; MHC Class I Antigen Precusor; HLA-A*02:01NEW; MHC Class I Protein (HLA-A); HLA-A Protein; HLA-A Locus Alpha 2 Domain; HLA Class I A; Lymphocyte Antigen M7-A2.2; Alpha1 Domain; MHC Class I Antigen R69772; MHC Class I; Human Leukocyte Antigen A; HLA-A*24var; HLA-A*24:02:01:01 Variant; HLA-A*0210; MHC Class I Antigen HLA-A; HLA-A*2903; Cell Surface Glycoprotein; HLA-A-6802; Leucocyte Antigen Class I; HLA-A-0203; Leukocyte Antigen Class I; HLA-A*3303; Transplantation Antigen; HLA-A*0218; HLA Class I Heavy Chain; HLA-A2 SLU; HLA-A11 Antigen A11.2; HLA-A-02; MHC Class I Antigen A; HLA-A-32; MHC Leukocyte Antigen; HLA-A30; MHC Class II Antigen; HLA-A25; MHC Class I Antigene; HLA-A26; Cell Surface Antigen; HLA-A*; HLA-A Alpha 1 Domain; HLA-A2; MHC Class I Antigen; A1102; MHC Class I Protein; Hla-A; HLA Class I Antigen; HLA-H; Leucocyte Antigen A; HLA_A; MCH Class I Antigen; HLA; B2M; beta 2-Microglobulin; beta-2-Microglobulin; beta-2-Microglobin; beta Chain Of MHC Class I Molecules; AMYLD6; beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr beta Chain
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
