735 Results for "

beta2

" in MedChemExpress (MCE) Product Catalog:
Products (735)

735 Results for "beta2" in MCE Product Catalog:

12
12 Cited Publications
Cat. No.: HY-N2037
CAS No.: 5843-65-2
Synonyms: Norcoclaurine; Demethyl-Coclaurine
Higenamine (Norcoclaurine), a β2-AR agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor (β2-AR). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases [2] .
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10
10 Cited Publications
Cat. No.: HY-P7365
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NRG1; NRG1 Class VII Isoform Alpha 2a; Prev. HGL; NRG1 Class VII Isoform beta 2a; Prev. NRG1-IT2; Neuregulin 1 Isoform HRG-Gamma; NDF; Neuregulin 1 Isoform HRG-beta3; GGF; Neuregulin 1 Isoform HRG-beta2; Pro-Neuregulin-1, Membrane-Bound Isoform; Neureguli
Species:  
Human
Source:  
E. coli
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8
8 Cited Publications
Cat. No.: HY-B1037
CAS No.: 18559-94-9
Synonyms: Albuterol; AH-3365
Target:  

Adrenergic Receptor ERK

Research Areas:  

Inflammation/Immunology Cancer

Salbutamol (Albuterol) is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease [2].
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8
8 Cited Publications
Cat. No.: HY-B0436
CAS No.: 51022-70-9
Synonyms: Albuterol hemisulfate; AH-3365 hemisulfate
Target:  

Adrenergic Receptor ERK

Research Areas:  

Inflammation/Immunology Cancer

Salbutamol (Albuterol) hemisulfate is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol hemisulfate promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol hemisulfate can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease [2].
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8
8 Cited Publications
Cat. No.: HY-14302
CAS No.: 89365-50-4
Purity:  99.70%
Synonyms: GR33343X
Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively .
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8
8 Cited Publications
Cat. No.: HY-17453
CAS No.: 94749-08-3
Synonyms: GR 33343X xinafoate
Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively .
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8
8 Cited Publications
Cat. No.: HY-112769
CAS No.: 1219739-36-2
Purity:  98.92%
Target:  

AMPK

Research Areas:  

Metabolic Disease

EX229, a Benzimidazole derivative, is a potent and allosteric activator of AMP-activated protein kinase (AMPK), with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1 and α1β2γ1 in biolayer interferometry, respectively.
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7
7 Cited Publications
Cat. No.: HY-B0010
CAS No.: 43229-80-7
Synonyms: (±)Formoterol fumarate
Target:  

Adrenergic Receptor

Research Areas:  

Inflammation/Immunology

Formoterol fumarate ((±)Formoterol fumarate) is a selective β2-adrenoceptor agonist. Formoterol fumarate is at least as β2-adrenoceptor selective as Salbutamol (HY-B1037) and Terbutaline (HY-B0802A). Formoterol fumarate abolishs the contraction induced by Acetylcholine in bronchioles. Formoterol fumarate can be used for the research of chronic obstructive pulmonary disease and bronchial asthma [2].
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7
7 Cited Publications
Cat. No.: HY-B0010B
CAS No.: 73573-87-2
Synonyms: (±)Formoterol
Target:  

Adrenergic Receptor

Research Areas:  

Inflammation/Immunology

Formoterol ((±)Formoterol) is a selective β2-adrenoceptor agonist. Formoterol is at least as β2-adrenoceptor selective as Salbutamol (HY-B1037) and Terbutaline (HY-B0802A). Formoterol abolishs the contraction induced by Acetylcholine in bronchioles. Formoterol can be used for the research of chronic obstructive pulmonary disease and bronchial asthma [2].
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7
7 Cited Publications
Cat. No.: HY-108901
CAS No.: 183814-30-4
Purity:  99.91%
Formoterol hemifumarate hydrate is a selective, long-acting beta 2-adrenoceptor agonist. Formoterol is a bronchodilator used for the research of the asthma and chronic obstructive pulmonary disease (COPD). Formoterol hemifumarate hydrate induces mitochondrial biogenesis and promotes cognitive recovery after traumatic brain injury [2] .
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6
6 Cited Publications
Cat. No.: HY-14300
CAS No.: 503068-34-6
Purity:  99.30%
Synonyms: GW642444
Vilanterol (GW642444) is a long-acting β2 adrenergic receptor agonist. Vilanterol has pEC50 values for β2-AR, β1-AR, and β3-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol selectively activates airway β2 adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol can be used in asthma research [3][5].
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6
6 Cited Publications
Cat. No.: HY-14300A
CAS No.: 503070-58-4
Purity:  99.82%
Synonyms: GW642444 trifenatate
Vilanterol (GW642444) trifenatate is a long-acting β2 adrenergic receptor agonist. Vilanterol trifenatate has pEC50 values for β2-AR, β1-AR, and β3-AR of 9.4, 6.4, and 6.1, respectively. Vilanterol trifenatate selectively activates airway β2 adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol trifenatate can be used in asthma research [2][4].
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6
6 Cited Publications
Cat. No.: HY-B1614
CAS No.: 21898-19-1
Synonyms: NAB-365 hydrochloride
Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage [2] .
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6
6 Cited Publications
Cat. No.: HY-129029
CAS No.: 66722-44-9
Purity:  99.78%
Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research [2].
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6
6 Cited Publications
Cat. No.: HY-B0076
CAS No.: 104344-23-2
Bisoprolol hemifumarate is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol hemifumarate has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research [2].
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5
5 Cited Publications
Cat. No.: HY-15746
CAS No.: 49745-95-1
Purity:  99.60%
Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion [2] .
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5
5 Cited Publications
Cat. No.: HY-15746A
CAS No.: 34368-04-2
Dobutamine is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine can increase cardiac output and correct hypoperfusion [2] .
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5
5 Cited Publications
Cat. No.: HY-14299
CAS No.: 312753-06-3
Purity:  99.98%
Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research [2].
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5
5 Cited Publications
Cat. No.: HY-14299A
CAS No.: 753498-25-8
Purity:  99.82%
Synonyms: QAB149
Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [2].
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4
4 Cited Publications
Cat. No.: HY-P7103A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-beta-2; IL-6; BSF-2; Interleukin-6; CDF; BSF2; Interleukin 6 (Interferon, beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated Interleukin 6; B-Cell Stimulatory Factor 2; Interferon, beta 2; CTL Differ
Species:  
Rat
Source:  
HEK293
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