Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
118 Results for "
BD2
" in MedChemExpress (MCE) Product Catalog:
Products (118)
118 Results for "BD2" in MCE Product Catalog:
Cat. No.: HY-177139
CAS No.: 2757619-90-0
Target:
Cat. No.: HY-126325
CAS No.: 2247236-59-3
Target:
Research Areas:
BY27 is a potent and selective BET BD2 inhibitor, shows 38, 5, 7, and 21-fold BD1/BD2 selectivity for BRD2, BRD3, BRD4, and BRDT. Anti-cancer activity .
Cat. No.: HY-177143
CAS No.: 2757619-87-5
Target:
Research Areas:
CDD-1498 (Compound 12) is a potent inhibitor of BRDT-BD2. CDD-1498 has an IC50 of 978 nM against BRDT-BD2. CDD-1498 can be studied in research on nonhormonal contraceptive agent .
Cat. No.: HY-177144
CAS No.: 2757619-86-4
Target:
Research Areas:
CDD-1128 (Compound 11) is a potent inhibitor of BRDT-BD2. CDD-1128 has an IC50 of 521 nM against BRDT-BD2. CDD-1128 can be studied in research on nonhormonal contraceptive agent .
Cat. No.: HY-177145
CAS No.: 2757619-83-1
Target:
Research Areas:
CDD-1132 (Compound 8) is a potent inhibitor of BRDT-BD2. CDD-1132 has an IC50 of 13 nM against BRDT-BD2. CDD-1132 can be studied in research on nonhormonal contraceptive agent .
Cat. No.: HY-W101666
CAS No.: 2138-48-9
Target:
Research Areas:
3-Isopropylcatechol is a catechol produced by Rhodococcus erythropolis BD2 .
Cat. No.: HY-132232
CAS No.: 2159137-02-5
Target:
Research Areas:
GSK097 is a potent and selective Inhibitor of the second bromodomain (BD2) of the bromodomain and extra-terminal domain (BET) proteins. GSK097 displays 2000-fold selective for BD2 over BD1 (BRD4 data) with >1 mg/mL solubility in FaSSIF media .
Cat. No.: HY-149098
CAS No.: 2924546-70-1
Target:
Research Areas:
SJ1461 is a potent and orally active BET inhibitor. SJ1461 inhibits BRD2 (BD1), and BRD2 (BD2), BRD4 (BD1), and BRD4 (BD2) with IC50 values of 1.6 nM, 0.1 nM, 6.5 nM, and 0.2 nM, respectively .
Target:
Research Areas:
GSK852 is a highly potent, second bromodomain (BD2)-selective, bromo and extra-terminal domain (BET) inhibitor (pIC50 = 7.9).
Cat. No.: HY-177140
CAS No.: 2757619-89-7
Target:
Research Areas:
CDD-1147 is a BRDT-BD2 inhibitor with an IC50 of 94 nM. CDD-1147 can be used in the research of non-hormonal contraceptives for men .
Target:
Research Areas:
(S)-GSK852 is a diastereomer of GSK852 (HY-115867). GSK852 is a BET inhibitor targeting BD2 (pIC50=7.9) .
Cat. No.: HY-155809
Target:
Research Areas:
BET-IN-17 (compound 16) is a pan-inhibitor of BET with pIC50s of 7.8 and 7.6 for BET BD1 and BET BD2, respectively .
Cat. No.: HY-177141
CAS No.: 2757619-88-6
Target:
Research Areas:
CDD-1154 is an aminopyrimidine analog. CDD-1154 is a BRDT-BD2 inhibitor (IC50: 139 nM). CDD-1154 is used in male contraceptive research .
Cat. No.: HY-162621
Target:
Research Areas:
BET-IN-25 (compound 7) is an oral bioactive inhibitor of bromodomain (BD1) and BD2, with the IC50s of 0.18 μM and 9.2 μM, respectively .
Cat. No.: HY-142674
CAS No.: 1781219-19-9
Target:
Research Areas:
BRD4-BD1/2-IN-1 is a potent BRD4 inhibitor with IC50s of <100 nM for BRD4 BD-1 and BRD4 BD-2, respectively (US20150148375A1, compound 5) .
Cat. No.: HY-153242
CAS No.: 2748687-92-3
Target:
Research Areas:
GSK217
is a potent, selective, and highly soluble bromo and extraterminal domain (BET)
second bromodomain (BD2) inhibitor. GSK217 can be used for
the research of oncology and immune inflammation research .
Cat. No.: HY-153945
CAS No.: 2408994-22-7
Target:
Research Areas:
BET-IN-15 (compound 1) is a potent and orally active BET inhibitor with IC50 values of 0.64，0.25 nM for BRD4-BD1，BRD4-BD2，respectively. BET-IN-15 shows antiproliferative activity .
Cat. No.: HY-173062
CAS No.: 2994635-04-8
Target:
Research Areas:
BRD4 Inhibitor-40 (Compound 23) is the inhibitor for BRD that inhibits BRD4-BD1, BRD4-BD2, BRD2-BD1 and BRD2-BD2 with IC50s of 16.1, 142.18, 29.35 and 302.35 nM, respectively. BRD4 Inhibitor-40 modulates the expression of c-Myc and p21, arrests cell cycle at G1 phase, inhibits Pkd1-null (PN) renal cystic epithelial cells, and blocks the renal cysts formation in Madin-Darby canine kidney and embryonic kidney vesicle models. BRD4 Inhibitor-40 exhibits renal cysts inhibitory activity in mouse models .
Cat. No.: HY-163160
CAS No.: 2953287-57-3
Target:
Research Areas:
Bet-in-23 (Compound 23) is a BD2-selective BET inhibitor with an IC50 of 2.9 nM. BET-IN-23 has anticancer activity and can significantly inhibit the proliferation of acute myeloid leukemia (AML) cell lines by inducing G0/G1 arrest and apoptosis in vitro .
Cat. No.: HY-155078
CAS No.: 930039-92-2
Target:
Research Areas:
BRD4 Inhibitor-27 (compound 6) is a BRD4 inhibitor with IC50 of 9.6 and 11.3 μM for BRD4 BD1 and BRD4 BD2, respectively. BRD4 Inhibitor-27 has the potential to study cancer .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
