2. Epigenetics
  3. Epigenetic Reader Domain
  4. GSK097

GSK097 is a potent and selective Inhibitor of the second bromodomain (BD2) of the bromodomain and extra-terminal domain (BET) proteins. GSK097 displays 2000-fold selective for BD2 over BD1 (BRD4 data) with >1 mg/mL solubility in FaSSIF media.

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GSK097 Chemical Structure

GSK097 Chemical Structure

CAS No. : 2159137-02-5

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GSK097 Related Antibodies

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Description

GSK097 is a potent and selective Inhibitor of the second bromodomain (BD2) of the bromodomain and extra-terminal domain (BET) proteins. GSK097 displays 2000-fold selective for BD2 over BD1 (BRD4 data) with >1 mg/mL solubility in FaSSIF media[1].

In Vitro

GSK097 displays pIC50s 7.4, 8.0, 7.6, and 7.9 for BRD2 BD2, BRD3 BD2, BRD4 BD2 and BRDT BD2, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GSK097 Related Antibodies
Molecular Weight

339.39

Formula

C19H21N3O3
CAS No.
SMILES

O=C(C1=NC([C@@H](O)C2=CC=CC=C2)=CC(C(N[C@@H]3[C@@H](C)C3)=O)=C1)NC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GSK097 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK0972159137-02-5GSK 097GSK-097Epigenetic Reader DomainBD2selectivebromodomainFaSSIFmediaInhibitorinhibitorinhibit

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