92 Results for "

EMD

" in MedChemExpress (MCE) Product Catalog:
Products (92)

92 Results for "EMD" in MCE Product Catalog:

Cat. No.: HY-W705589
Synonyms: EMD-87580-15N3 hydrochloride
Rimeporide- 15N3 (hydrochloride) (EMD-87580- 15N3 (hydrochloride)) is 15N labeled Rimeporide hydrochloride. Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective inhibitor of the Na +/H + exchanger (NHE-1).
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Cat. No.: HY-105112
CAS No.: 98323-83-2
Synonyms: EMD 45609
Target:  

Dopamine Receptor

Research Areas:  

Cardiovascular Disease

Carmoxirole (EMD 45609) is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo .
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Cat. No.: HY-100820B
CAS No.: 177976-12-4
Synonyms: EMD 128130 dihydrochloride
Research Areas:  

Neurological Disease

Sarizotan dihydrochloride (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively .
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Cat. No.: HY-RS04345
Research Areas:  

Others

EMD Human Pre-designed siRNA Set A contains three designed siRNAs for EMD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17358
Research Areas:  

Others

Emd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Emd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23812
Research Areas:  

Others

Emd Rat Pre-designed siRNA Set A contains three designed siRNAs for Emd gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-103410R
CAS No.: 115092-85-8
Synonyms: EMD 45609 hydrochloride (Standard)
Carmoxirole (hydrochloride) (Standard) is the analytical standard of Carmoxirole (hydrochloride). This product is intended for research and analytical applications. Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective, peripherally acting dopamine D2 receptor agonist and exhibits antihypertensive activities in vivo .
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Cat. No.: HY-100820R
CAS No.: 351862-32-3
Synonyms: EMD 128130 (Standard)
Sarizotan (Standard) is the analytical standard of Sarizotan. This product is intended for research and analytical applications. Sarizotan (EMD 128130) is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively .
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Cat. No.: HY-P0322A
Synonyms: EMD 56574 TFA
Target:  

Integrin

GRGDSPK TFA (EMD 56574 TFA) is a peptide incluing Arg-Gly-Asp (RGD). GRGDSPK TFA is an competitive and reversible inhibitory peptide for inhibiting integrin-fibronectin binding. GRGDSPK TFA is used to study the role of integrins in bone formation and resorption .
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Cat. No.: HY-14261R
CAS No.: 163521-08-2
Synonyms: EMD 68843 Hydrochloride (Standard); SB659746A Hydrochloride (Standard)
Vilazodone (Hydrochloride) (Standard) is the analytical standard of Vilazodone (Hydrochloride). This product is intended for research and analytical applications. Vilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT1A receptor partial agonist.
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Cat. No.: HY-106100
CAS No.: 112192-04-8
Synonyms: EMD 49980
Roxindole (EMD 49980), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor. Antipsychotic and antidepressant activities .
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Cat. No.: HY-175878
Research Areas:  

Cancer

EMD-C02602 is a GCN2-targeting agent with IC50 values of 0.023 μM, 4.52 μM, > 10 μM and 0.048 μM for GCN2, PERK, HRland PKR, respectively .
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Cat. No.: HY-100820A
CAS No.: 195068-07-6
Synonyms: EMD 128130 hydrochloride
Research Areas:  

Neurological Disease

Sarizotan hydrochloride is an orally active serotonin 5-HT1A receptor and dopamine receptor agonist. Sarizotan hydrochloride (EMD 128130) exhibits IC50 values of 6.5 nM (rat 5-HT1A), 0.1 nM (human 5-HT1A), 15.1 nM (rat D2), 17 nM (human D2), 6.8 nM (human D3) and 2.4 nM (human D4.2), respectively .
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Cat. No.: HY-14262R
CAS No.: 163521-12-8
Synonyms: EMD 68843 (Standard); SB659746A (Standard)
Vilazodone (Standard) is the analytical standard of Vilazodone. This product is intended for research and analytical applications. Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active serotonin reuptake inhibitor (SSRI) and partial 5-HT1A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders .
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Cat. No.: HY-106100AR
CAS No.: 108050-82-4
Synonyms: EMD 38362 (Standard)
Roxindole (hydrochloride) (Standard) is the analytical standard of Roxindole (hydrochloride). This product is intended for research and analytical applications. Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities .
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Cat. No.: HY-106472
CAS No.: 40198-53-6
Synonyms: EMD 26644
Target:  

Bacterial

Research Areas:  

Infection

Tioxaprofen is a new anti-mycotic drug against Trichophyton mentagrophytes and T. rubrum, and is a potent uncoupling agent of mitochondrial respiration .
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Cat. No.: HY-P990076
CAS No.: 2131168-99-3
Synonyms: APN-301; hu14.18-IL2; EMD 273063

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine consisting of the humanized 14.18 anti-GD2 mAb linked to IL210. Lorukafusp alfa has activity mediated by activation of antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity via the binding of hu14.18-IL2 to GD2 on the tumor cell surface, followed by binding to Fc receptors on effector cells along with activation of NK and T cells via IL2 receptor binding. Lorukafusp alfa has anti-tumor activity .
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Cat. No.: HY-107030R
CAS No.: 21721-92-6
Synonyms: EMD-15700 (Standard)
Nitrefazole (Standard) is the analytical standard of Nitrefazole. This product is intended for research and analytical applications. Nitrefazole is a 4-nitroimidazole derivative with strong and long lasting inhibition of aldehyde dehydrogenase (ALDH), an enzyme involved in the metabolism of alcohol.
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Cat. No.: HY-70057S4
Synonyms: FCE 26743-d5; EMD 1195686-d5
Safinamide-d5 (FCE 26743-d5) is deuterium labeled Safinamide. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 μM) . Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8?μM) than at resting (IC50=262?μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al .
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Cat. No.: HY-106150A
CAS No.: 190368-98-0
Research Areas:  

Cardiovascular Disease

Eniporide mesylate (EMD 96785 mesylate) is a Na(+)/H(+) exchange (NHE) inhibitor. Eniporide mesylate specifically inhibits the NHE-1 isoform. Eniporide mesylate improves cardiac performance inhibition associated with myocardial ischemia/reperfusion in animals, and limits infarct size in experimental models. Eniporide mesylate regulates cardiac performance and high-energy phosphate content .
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