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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
104 Results for "
KATP
" in MedChemExpress (MCE) Product Catalog:
Products (104)
104 Results for "KATP" in MCE Product Catalog:
Cat. No.: HY-B0682S2
Cat. No.: HY-B0682S1
Cat. No.: HY-17398R
CAS No.: 145525-41-3
Synonyms: KAD-1229 anhydrous (Standard); S21403 anhydrous (Standard)
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Mitiglinide (calcium) (Standard) is the analytical standard of Mitiglinide (calcium). This product is intended for research and analytical applications. Mitiglinide Calcium (KAD-1229 anhydrous), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide Calcium is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide Calcium can be used for the research of type 2 diabetes .
Cat. No.: HY-B0682AR
CAS No.: 207844-01-7
Synonyms: KAD-1229 (Standard); S-21403 (Standard)
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Mitiglinide (calcium hydrate) (Standard) is the analytical standard of Mitiglinide (calcium hydrate). This product is intended for research and analytical applications. Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K + (KATP) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes .
Cat. No.: HY-W777434
Cat. No.: HY-B0682S
Cat. No.: HY-119306
CAS No.: 181238-67-5
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MCC-134, a blocker of mitochondrial and opener of surface ATP-sensitive K+ (KATP) channels, abrogates cardioprotective effects of chronic hypoxia. MCC-134 is a vasorelaxing agent .
Cat. No.: HY-17451R
CAS No.: 26944-48-9
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Glibornuride (Standard) is the analytical standard of Glibornuride. This product is intended for research and analytical applications. Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75 . Antidiabetic agent .
Cat. No.: HY-15206S2
Synonyms: Glyburide-13C6
Cat. No.: HY-114690
CAS No.: 179474-69-2
Synonyms: BVT.3531
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PNU-140975 (BVT.3531) is a novel and potent bioactive compound. PNU-140975 can reduce body weight and activates KATP channel in isolated arcuate neurons in rats .
Cat. No.: HY-U00201
CAS No.: 152802-84-1
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KRN4884 is a K + channel opener. In the presence of intracellular ATP (1 mM), KRN4884 (0.1-3 μM) activates KATP channels in a concentration-dependent manner (EC50=0.55 μM).
Cat. No.: HY-117283
CAS No.: 89544-10-5
Synonyms: rel-RP 52891
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rel-Aprikalim (rel-RP 52891) is the relative configuration of Aprikalim (HY-121183). Aprikalim (RP 52891), a potassium channel opener (KCO), activates ATP-sensitive K + (KATP) channels in guinea pig ventricular myocytes .
Cat. No.: HY-117255
CAS No.: 161229-62-5
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ZM260384 is a KATP channel opener that accelerates metabolism and inhibits the decline of guinea pig isolated diaphragm function, thereby affecting muscle contraction. ZM260384 can be used to study muscle function under hypoxic conditions .
Cat. No.: HY-14257
CAS No.: 166095-95-0
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BMS-191095 hydrochloride is a mitochondrial KATP channel opener. BMS-191095 hydrochloride can protect the myocardium without causing vasodilation or affecting electrophysiology, by prolonging the contraction time during ischemia, improving contractile function after reperfusion, and reducing lactate dehydrogenase (LDHM) release, thereby exerting its cardioprotective effects .
Cat. No.: HY-115014
CAS No.: 100678-32-8
Synonyms: Cifenline succinate; Ro 22-7796 succinate
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Cibenzoline succinate (Cifenline succinate) is the succinate form of Cibenzoline (HY-106577). Cibenzoline succinate is an inhibitor for ATP-sensitive potassium (KATP) channel by affecting the pore-forming Kir6.2 subunit with IC50 of 22.2 µM. Cibenzoline succinate affects insulin secretion and exhibits antiarrhythmic and antidiabetic activities .
Cat. No.: HY-113147S1
CAS No.: 2847775-90-8
Cat. No.: HY-113147AR
CAS No.: 18877-64-0
Cat. No.: HY-152013S
CAS No.: 2692623-98-4
Cat. No.: HY-B0341R
CAS No.: 65141-46-0
Synonyms: SG-75 (Standard)
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Nicorandil (Standard) is the analytical standard of Nicorandil. This product is intended for research and analytical applications. Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K + channels and cardiac ATP-sensitive K + channels (KATP). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases .
Cat. No.: HY-N1504R
CAS No.: 119425-90-0
Category:
Dracaena cochinchinensis (Lour.) S. C. Chen Flavonoids Monophenols Phenols Agavaceae Extract Plants Dihydrochalcones
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
