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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
136 Results for "
CaV
" in MedChemExpress (MCE) Product Catalog:
Products (136)
136 Results for "CaV" in MCE Product Catalog:
Cat. No.: HY-17402S
CAS No.: 1285910-03-3
Synonyms: BAY-k 5552-d6
Cat. No.: HY-17402R
CAS No.: 63675-72-9
Synonyms: BAY-k 5552 (Standard)
Research Areas:
Nisoldipine (Standard) is the analytical standard of Nisoldipine. This product is intended for research and analytical applications. Nisoldipine (BAY-k 5552; Sular) is a highly efficient and specific L-type Cav1.2 channel blocker with an IC50 of 10 nM.
Cat. No.: HY-17402S3
CAS No.: 1432057-47-0
Synonyms: BAY-k 5552-d3
Cat. No.: HY-P2288
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Cat. No.: HY-P5793
Target:
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Cat. No.: HY-P5869
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Cat. No.: HY-17402S1
CAS No.: 1219795-47-7
Cat. No.: HY-17402S2
CAS No.: 1189718-34-0
Cat. No.: HY-B0166S4
Synonyms: L-Ascorbate-13C-3; Vitamin C-13C-3
Cat. No.: HY-169845
CAS No.: 687568-35-0
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Research Areas:
Calcium Channel antagonist 6 (Compound 328) is a highly selective antagonist of voltage-gated calcium channel CaV2.2 with an IC50 value of 0.37 μM. Calcium Channel antagonist 6 inhibits of neuron depolarization-induced Ca 2+ influx. Calcium Channel antagonist 6 is promising for research of neuropathic pain .
Cat. No.: HY-118202
CAS No.: 36622-40-9
Synonyms: (-)-Methoxyverapamil
Target:
Research Areas:
(-)-Gallopamil exerts a selective modulation of the fast voltage-dependent inactivation. (-)-Gallopamil inhibits efficiently Cav1.2 constructs formed by β-subunits (promoting fast voltage-dependent inactivation). (-)-Gallopamil also accelerates the voltage-dependent phase of ICa decay (as well as the voltage-dependent decay of Ba 2+ currents). (-)-Gallopamil is promising for research of antiarrhythmics .
Cat. No.: HY-118202A
CAS No.: 36622-39-6
Synonyms: (-)-Methoxyverapamil hydrochloride
Target:
Research Areas:
(-)-Gallopamil (hydrochloride) exerts a selective modulation of the fast voltage-dependent inactivation. (-)-Gallopamil (hydrochloride) inhibits efficiently Cav1.2 constructs formed by β-subunits (promoting fast voltage-dependent inactivation). (-)-Gallopamil (hydrochloride) also accelerates the voltage-dependent phase of ICa decay (as well as the voltage-dependent decay of Ba 2+ currents). (-)-Gallopamil (hydrochloride) is promising for research of antiarrhythmics .
Cat. No.: HY-122552
CAS No.: 108853-09-4
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Cat. No.: HY-P5874
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Cat. No.: HY-159090
CAS No.: 3053482-15-5
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AT1R antagonist 3 (Compound 1) is an antagonist for angiotensin II type 1 receptor (AT1R) and an inhibitor for calcium channel type-L CaV1.2 (IC50=0.57 μM). AT1R antagonist 3 exhibits vasodilation efficacy in solated rat aorta (10 μM, 88.7%) and antihypertensive efficacy in rat models .
Cat. No.: HY-P5813
Synonyms: β-TRTX-cd1a; β-Theraphotoxin-cd1a
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Cat. No.: HY-146173
Target:
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KCa1.1 channel activator-1 (compound 1E), a Quercetin hybrid derivative, is a selective vascular KCa1.1 channel channel stimulator. KCa1.1 channel activator-1 also displays CaV1.2 channel blocking activity. KCa1.1 channel activator-1 exhibits weak myorelaxant activity .
Cat. No.: HY-N12859
CAS No.: 135010-45-6
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Cat. No.: HY-136189
CAS No.: 2250025-89-7
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UK-59811 hydrochloride, a Br-dihydropyridine derivative, is a potent bacterial homotetrameric model voltage-gated Ca 2+ (CaV) channel CaVAb inhibitor with an IC50 of 194 nM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
