Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
136 Results for "
CaV
" in MedChemExpress (MCE) Product Catalog:
Products (136)
136 Results for "CaV" in MCE Product Catalog:
Target:
Research Areas:
SAK3 is a potent T-type voltage-gated Ca 2+ channels (T-VGCCs) enhancer. SAK3 enhances Cav3.1 and Cav3.3 T-type Ca 2+ channel currents. Acute SAK3 administration improves memory deficits in olfactory-bulbectomized mice . SAK3 inhibits amyloid β plaque formation in APP-KI mice by activating the proteasome activity .
Cat. No.: HY-B0166S6
CAS No.: 82977-10-4
Synonyms: L-Ascorbate-d2; Vitamin C--d2
Cat. No.: HY-B0166S1
CAS No.: 178101-88-7
Synonyms: L-Ascorbate-13C; Vitamin C-13C
Target:
Research Areas:
N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC50 values of 55 μM and 37 μM for Cav1.2 and Cav1.3, respectively .
Cat. No.: HY-164803
CAS No.: 1281060-70-5
Target:
Research Areas:
CBD3063 is a selective modulator of collapsin response mediator protein 2 (CRMP2). CBD3063 uncouples Cav2.2 from CRMP2. CBD3063 reverses neuropathic and inflammatory pain by reducing membrane expression of CaV2.2 .
Cat. No.: HY-RS01986
Target:
Research Areas:
CAV1 Human Pre-designed siRNA Set A contains three designed siRNAs for CAV1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P3269
CAS No.: 178805-91-9
Target:
Research Areas:
Target:
Research Areas:
BTT-266 is an antagonist forcalcium channel, through suppression of the CaVα1-AID-CaVβ3 interaction, with a Ki of 1.4 μM. BTT-266 modulates the activation of voltage-dependent CaV2.2. BTT-266 exhibits analgesic efficacy against neuropathic pain in rats model .
Target:
Research Areas:
Cav 2.2 blocker 2 is a Cav2.2 calcium channel blocker extracted from patent WO2017046581A1, compound 1. Cav 2.2 blocker 2 can reverses hyperalgesia associated with an injury or inflammation in conjunction with the opioid .
Cat. No.: HY-Z7760
CAS No.: 91189-59-2
Target:
Research Areas:
Felodipine 3,5-Dimethyl Ester is a aryldihydropyridine derivatives for use as mineralocorticoid receptor modulator and voltage-dependent L-type calcium channel CaV1.2 inhibitor .
Cat. No.: HY-148866
CAS No.: 2143584-82-9
Target:
Research Areas:
Cavα2δ1&NET-IN-3 (example 216) is an inhibitor of the subunit α2δ of voltage-gated calcium channels (VGCC) and noradrenaline transporter (NET). Cavα2δ1&NET-IN-3 has Kis of 100-500 nM for human α2δ-1 subunit of Cav2.2 calcium channel and NET, respectively .
Cat. No.: HY-B0166S3
CAS No.: 1313730-17-4
Synonyms: L-Ascorbate-13C-2; Vitamin C-13C-2
Cat. No.: HY-151452
CAS No.: 2878598-69-5
Target:
Research Areas:
Cav 3.2 inhibitor 3 (Compound 4) is a potent Cav3.2 T-type Ca 2+ channel inhibitor with an IC50 of 0.1534 μM, and has little binding affinity to D2 receptors .
Cat. No.: HY-RS01987
Target:
Research Areas:
CAV2 Human Pre-designed siRNA Set A contains three designed siRNAs for CAV2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23990
Target:
Research Areas:
Cav1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cav1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-126336
CAS No.: 2376051-91-9
Target:
Research Areas:
HM12 is a covalent inhibitor of L-/T-type calcium channels. HM12 can strongly inhibit the Cav1.2 (L-type) and Cav3.2 (T-type) calcium channels, and has selectivity for the N-type channels. HM12 produces an irreversible inhibition that persisted after washout. HM12 can be used to study diseases such as hypertension, pain, epilepsy, etc .
Cat. No.: HY-148863
CAS No.: 2143586-17-6
Target:
Research Areas:
Cavα2δ1&NET-IN-2 (Compound 45CS) is a dual inhibitor of the α2δ‑1 subunit of voltage-gated calcium channels (Cavα2δ-1) and the norepinephrine transporter (NET). Cavα2δ1&NET-IN-2 inhibits Cavα2δ-1 with a Ki of 454 nM. Cavα2δ1&NET-IN-2 inhibits NET with a Ki of 59 nM and IC50 of 7 nM. Cavα2δ1&NET-IN-2 can be used for research of pain .
Cat. No.: HY-B0166S2
CAS No.: 178101-89-8
Synonyms: L-Ascorbate-13C-1; Vitamin C-13C-1
Cat. No.: HY-B0166S5
CAS No.: 149153-08-2
Synonyms: L-Ascorbate-13C-4; Vitamin C-13C-4
Cat. No.: HY-P10898
CAS No.: 2900996-95-2
Target:
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
