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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
270 Results for "
ECL4 loop
" in MedChemExpress (MCE) Product Catalog:
Products (270)
270 Results for "ECL4 loop" in MCE Product Catalog:
Cat. No.: HY-177777
Domaines de recherche:
FL2-14 is a CRBN-dependent selective molecular glue degrader of GSPT2. FL2-14 specifically degrades GSPT2 by recruiting the CRBN E3 ligase to recognize the G-loop sequence on the target protein GSPT2. FL2-14 can be used in related research on colorectal cancer .
Cat. No.: HY-P10550
Cat. No.: HY-163513
CAS No.: 2515609-54-6
Target:
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AACA is an inhibitor for sclerostin, that binds sclerostin on loop3 region with Kd of 15.4 nM. AACA exhibits anti-osteoporosis activity through Wnt signaling pathway .
Synonyms: MG-13054
Target:
Domaines de recherche:
Fenquizone (MG-13054) is an orally active diuretic. Fenquizone acts primarily on the diluting segment of the nephron cortex, similar to thiazide diuretics. Fenquizone demonstrates diuretic and natriuretic potency and duration of action comparable to thiazide diuretics but weaker than loop diuretics. Fenquizone reduces CH₂O without affecting TCH₂O, does not increase calcium/phosphate excretion, and has no loop or collecting duct effects. Fenquizone is used in the study of edema and hypertension .
Cat. No.: HY-177980
CAS No.: 110138-50-6
Target:
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DNA-GAGA is a slow substrate for Ricin toxin A-chain (RTA). RTA depurinates a single adenylate on a GAGA stem-loop region of eukaryotic 28S RNA, making it a potent toxin .
Cat. No.: HY-177979
CAS No.: 54230-76-1
Target:
Domaines de recherche:
DNA-GAG is a slow substrate for Ricin toxin A-chain (RTA). RTA depurinates a single adenylate on a GAGA stem-loop region of eukaryotic 28S RNA, making it a potent toxin .
Cat. No.: HY-P1594
CAS No.: 79994-24-4
Target:
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Cat. No.: HY-129372
CAS No.: 2101206-44-2
Target:
Domaines de recherche:
PDdB-Pfp is a cleavable ADC linker used for the agents that target for the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1) .
Cat. No.: HY-161693
CAS No.: 3047091-81-3
Target:
Domaines de recherche:
Telomeric G4s ligand 1 is a telomeric G-quadruplex ligand that stabilizes telomeric G4 and induces R-loop formation, leading to DNA damage responses. Telomeric G4s ligand 1 induces apoptosis and evokes immunogenic cell death (ICD) in tumor cells .
Cat. No.: HY-174575
Human MYOD1 mRNA encodes the human myogenic differentiation 1 (MYOD1) protein, a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. MYOD1 acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
Cat. No.: HY-P11131
Synonyms: Human lactoferrin (28-34)
Cat. No.: HY-E70746
MEK1 is the MAP/ERK kinase. The MEK1 kinase directly phosphorylates ERK2, after the activation loop of MEK1 is itself phosphorylated by Raf. MEK1 SESE is a mutant of MEK1. MEK1 SESE Recombinant Human Active Protein Kinase is a recombinant MEK1 SESE protein that can be used to study MEK1 SESE-related functions .
Cat. No.: HY-P1598
Target:
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Target:
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Etozolin (W-2900A) is a diuretic agent. Etozolin inhibits fluid and electrolyte reabsorption in the loop of Henle. Etozolin can be used in research of congestive heart failure, hypertension and edema .
Cat. No.: HY-W111168
CAS No.: 3270-25-5
Cat. No.: HY-174571
Target:
Domaines de recherche:
Human NEUROG2 mRNA encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells. NEUROG2 plays a role in the differentiation and survival of midbrain dopaminergic neurons.
Cat. No.: HY-P5228
CAS No.: 2439064-83-0
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Cat. No.: HY-P5229
CAS No.: 2439064-86-3
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
