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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
185 Results for "
Exatecan
" in MedChemExpress (MCE) Product Catalog:
Products (185)
185 Results for "Exatecan" in MCE Product Catalog:
Cat. No.: HY-42487R
CAS No.: 110351-94-5
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Exatecan Intermediate 1 (Standard) is the analytical standard of Exatecan Intermediate 1. This product is intended for research and analytical applications. Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor with anticancer effects .
Cat. No.: HY-176977
CAS No.: 3076725-07-7
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Exatecan-mpGly-Asn-Asn-(βAla) (Compound 10b) is a conjugate of Exatecan (HY-13631) and a linker. Exatecan-mpGly-Asn-Asn-(βAla) can be used to synthesize ADCs, such as α-HER2_mpGlyAsnAsn(β-Ala)_Exatecan. Exatecan-mpGly-Asn-Asn-(βAla) can also be used in tumor research .
Cat. No.: HY-157795
CAS No.: 2671770-58-2
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Exatecan analogue 1 (Icp-3) is a Exatecan (HY-13631) analogue. Exatecan analogue 1 can be used in the synthesis of antibody-drug conjugates (ADCs)
Cat. No.: HY-46081
CAS No.: 3040182-19-9
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Exatecan Intermediate 3 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 3 can be used to synthesize Antibody-Drug Conjugates (ADCs).
Cat. No.: HY-47858
CAS No.: 1599440-09-1
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Exatecan-2-(aminomethoxy)acetamide-Gly-Fmoc is an ADC cytotoxin.
Cat. No.: HY-48878
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Exatecan analog 36 is a analog of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
Cat. No.: HY-178315
CAS No.: 2766214-00-8
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Exatecan analog 38 is a camptothecin derivative with potent topoisomerase I inhibitory activity. Exatecan analog 38 can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan analog 38 can be used for cancer research .
Cat. No.: HY-178289
CAS No.: 2901788-26-7
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Fmoc-Val-Lys(Boc)-PAB-Exatecan (Compound 39-7) is a Drug-Linker Conjugates for ADC. Fmoc-Val-Lys(Boc)-PAB-Exatecan consists of the ADC Cytotoxin Exatecan (HY-13631) and a linker PAB-Val-Lys-Boc (HY-138651). Fmoc-Val-Lys(Boc)-PAB-Exatecan can be used for synthesis of ADCs .
Cat. No.: HY-153069A
Research Areas:
GGFG-PAB-Exatecan TFA consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules .
Cat. No.: HY-13631AS1
Synonyms: DX8951f-d3 mesylate
Cat. No.: HY-177879
CAS No.: 2878440-72-1
Research Areas:
2-MSP-5-HA-Val-Cit-PAB-Exatecan (A-24) is a drug-linker conjugate for ADC. 2-MSP-5-HA-Val-Cit-PAB-Exatecan consists of Exatecan (HY-13631) and a linker. 2-MSP-5-HA-Val-Cit-PAB-Exatecan can be used for synthesis of ADCs .
Cat. No.: HY-160597
CAS No.: 2866299-06-9
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Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan (HY-13631) derivative that can be used as a payload in drug conjugates. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol has significant inhibitory activity against a variety of tumor cell lines .
Cat. No.: HY-160543
CAS No.: 2920907-39-5
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Exatecan-amide-CH2-O-CH2-CH2-OH (Compound 4) is a derivative of Exatecan (HY-13631). Exatecan-amide-CH2-O-CH2-CH2-OH can be used for the research of cell proliferative diseases such as cancer .
Cat. No.: HY-160598
CAS No.: 2891774-71-1
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Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol (compound 45) is a camptothecin compound that can inhibit cell proliferation, with an IC50 of 2.92 ng/mL for MDA‑MB‑468 cells. Exatecan-amide-bicyclo[1.1.1]pentan-1-ylmethanol can be used for the research of cancer .
Cat. No.: HY-148696B
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Gly-(S)-Cyclopropane-Exatecan is the isomer of Gly-Cyclopropane-Exatecan (HY-148696A).
Cat. No.: HY-43565B
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Exatecan intermediate 10 is an intermediate in the synthesis of Exatecan (HY-13631).Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 of 2 .2 μM (0 .975 μg/mL) for use in cancer research .
Cat. No.: HY-160756A
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Val-Cit-Exatecan TFA is an agent-linker conjugate for ADC. Val-Cit-Exatecan TFA is composed of a DNA topoisomerase I Exatecan (HY-13631) and a cathepsin cleavable ADC linker .
Cat. No.: HY-W021377C
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Exatecan Intermediate 4 dihydrochloride (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-42487A
CAS No.: 102978-40-5
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(rac)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
