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Cat. No.: HY-157795

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Exatecan analogue 1

Exatecan analogue 1 (Icp-3) is a Exatecan (HY-13631) analogue. Exatecan analogue 1 can be used in the synthesis of antibody-drug conjugates (ADCs)

For research use only. We do not sell to patients.

CAS No.: 2671770-58-2
Formula: C₂₃H₂₀FN₃O₄
Molecular Weight:421.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Exatecan analogue 1 Chemical Structure

CAS No.: 2671770-58-2

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Exatecan analogue 1 (Icp-3) is a Exatecan (HY-13631) analogue. Exatecan analogue 1 can be used in the synthesis of antibody-drug conjugates (ADCs)^[1]

IC₅₀ & Target

Camptothecins

All ADC Payloads Isoforms :

All Topoisomerase Isoforms :

Chemical Information

CAS No. 2671770-58-2
Molecular Weight 421.42
Formula C₂₃H₂₀FN₃O₄
SMILES

O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC(F)=C5N)=CC6=C1COC([C@]6(O)CC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Robert Yongxin Zhao, et al. Bcma monoclonal antibody and the antibody-drug conjugate. WO2023078021 A1. 2023-05-11.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Exatecan analogue 1

All ADC Payloads Isoforms

All Topoisomerase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Exatecan analogue 1 Related Classifications

HY-157795 Related Classifications