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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
197 Results for "
Innate immunity
" in MedChemExpress (MCE) Product Catalog:
Products (197)
197 Results for "Innate immunity" in MCE Product Catalog:
Cat. No.: HY-148420
CAS No.: 2586047-09-6
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CDN-A is a cyclic di-nucleotide, it can be used to synthesis antibody-drug conjugate (ADC). Cyclic di-nucleotides are potent stimulators of innate and adaptive immune responses. In humans, cyclic di-nucleotide, which are either produced endogenously in response to foreign DNA or by invading bacterial pathogens, trigger the innate immune system by activating the expression of interferon genes .
Cat. No.: HY-174496
eGFP mRNA (5moU) expresses a green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. EGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence. The substitution with 5’-Methoxyuridine (5moU) improves protein expression and reduces innate immune response.
Cat. No.: HY-147338
CAS No.: 327174-86-7
Synonyms: 5-Methyl-CTP
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5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) is a modified ribonucleoside 5′-triphosphate. When incorporated into mRNA, 5-Methylcytidine 5′-triphosphate enhances the translation efficiency and stability of the mRNA, and reduces the innate immune response. 5-Methylcytidine 5′-triphosphate can be used in studies related to gene replacement and vaccination applications .
Cat. No.: HY-150965
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NDT-30805 is a selective NLRP3 inflammasome inhibitor. NDT-30805 is a triazolopyrimidinone derivative and inhibits IL-1β release in PBMCs with an IC50 of 0.013 μM. NDT-30805 can be used for the research of inflammation and innate immunity .
Cat. No.: HY-162966
CAS No.: 3060519-67-4
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MS7829 is a deubiquitinase-targeting chimera (DUBTAC) that targets cGAS. MS7829 recruits OTUB1 to cGAS, binds covalently to OTUB1, stabilizes the protein abundance of cGAS, and activates the cGAS-STING-IRF3 innate immune signaling pathway in an OTUB1-dependent manner. MS7829 is applicable to cancer-related research .
Cat. No.: HY-174485
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OVA mRNA (N1-Me-Pseudo UTP) is an mRNA encoding chicken ovalbumin. The substitution with N1-Me-Pseudo UTP (m1Ψ) improves protein expression and reduces innate immune response. OVA mRNA binds to the STING-activating polymer PD18 and is encapsulated in optimized lipid nanoparticles to construct an mRNA vaccine platform (PD18 LNP). This platform not only enhances the lymphatic delivery efficiency and protein expression of mRNA, but also potently adjuvates immune responses via activating the STING pathway .
Cat. No.: HY-159100
CAS No.: 862810-50-2
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PVP-037 is a potent TLR7 and TLR8 agonist adjuvant. PVP-037 shows broad innate immune activation and enhances vaccine immune responses .
Cat. No.: HY-P2076A
Synonyms: SGX942 TFA
Cat. No.: HY-B0944R
CAS No.: 121808-62-6
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Pidotimod (Standard) is the analytical standard of Pidotimod. This product is intended for research and analytical applications. Pidotimod is an orally active dipeptide immunostimulant with immunomodulatory properties on the adaptive and the innate immune responses. Pidotimod increases macrophage activity and humoral immune functions. Pidotimod can be used for the research of chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchiectasis, and chronic idiopathic urticaria,et al .
Cat. No.: HY-E70728
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Heme-regulated inhibitory (HRI) is an eIF2α kinase, which induces a cytosolic unfolded protein response to prevent aggregation of innate immune signalosomes. HRI Recombinant Human Active Protein Kinase is a recombinant HRI protein that can be used to study HRI-related functions .
Cat. No.: HY-P2320
CAS No.: 940291-10-1
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Cat. No.: HY-156734
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D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 0.95 μM. D-4-77 has antiviral active with an EC50 value of 0.49 μM. D-4-77 suppresses SARS-CoV-2 Mpro -induced antagonism of the host NF-κB innate immune response .
Cat. No.: HY-174527
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Human TLR10 mRNA encodes the human toll like receptor 10 (TLR10) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR10 participates in the innate immune response to microbial agents.
Cat. No.: HY-177642
CAS No.: 852313-25-8
Synonyms: Li28
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Litenimod is potent type B agonist of toll Like receptor 9 (TLR9), triggering both innate and adaptive immune response.
Cat. No.: HY-177642A
Synonyms: Li28 sodium sodium
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Litenimod sodium is potent type B agonist of toll Like receptor 9 (TLR9), triggering both innate and adaptive immune response.
Cat. No.: HY-154921A
Synonyms: LacCer (porcine RBC)
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Lactosylceramide (LacCer) (porcine RBC) is an endogenous bioactive sphingolipid. Lactosylceramide (porcine RBC) plays a pivotal role in mediating innate immune functions .
Cat. No.: HY-P2291
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Cat. No.: HY-P2291A
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Cat. No.: HY-121397
CAS No.: 123048-17-9
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Phyltetralin (Compound 10) is a natural product than can be isolated from the hexane-ethyl acetate extract of Phyllanthus amarus leaves. Phyltetralin possesses immunosuppressive effects on different lineages of innate immune system .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
