276 Results for "

fibroblast cell

" in MedChemExpress (MCE) Product Catalog:
Products (276)

276 Results for "fibroblast cell" in MCE Product Catalog:

Cat. No.: HY-174694
Target:  

mRNA

Research Areas:  

Cancer

Human FGF6 mRNA encodes the human fibroblast growth factor 6 (FGF6) protein, a member of the fibroblast growth factor (FGF) family. FGF6 may play an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is also required for normal muscle regeneration.
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Cat. No.: HY-174706
Target:  

mRNA

Research Areas:  

Cardiovascular Disease

Human FGF16 mRNA encodes the human fibroblast growth factor 16 (FGF16) protein, a member of the fibroblast growth factor (FGF) family. FGF16 probably plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. It is also required for normal cardiomyocyte proliferation and heart development.
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Cat. No.: HY-174691
Target:  

mRNA

Research Areas:  

Cancer

Human FGF9 mRNA encodes the human fibroblast growth factor 9 (FGF9) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
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Cat. No.: HY-174692
Target:  

mRNA

Research Areas:  

Cancer

Human FGF8 mRNA encodes the human fibroblast growth factor 8 (FGF8) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
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Cat. No.: HY-174693
Target:  

mRNA

Research Areas:  

Cancer

Human FGF7 mRNA encodes the human fibroblast growth factor 7 (FGF7) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
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Cat. No.: HY-174699
Target:  

mRNA

Research Areas:  

Cancer

Human FGF22 mRNA encodes the human fibroblast growth factor 22 (FGF22) protein, a member of the fibroblast growth factor (FGF) family. FGF22 plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. It also can stimulate cell proliferation (in vitro) and may be involved in hair development.
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Cat. No.: HY-123195
CAS No.: 197917-10-5
Target:  

Interleukin Related

Research Areas:  

Cancer

CK-119 is a potent interleukin-1 blocker. CK-119 inhibits the cell growth of fibroblast-like corneal and conjunctival cells, mainly by inhibiting DNA and RNA syntheses .
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Cat. No.: HY-W773183
CAS No.: 4356-31-4
Synonyms: Betulonic acid methyl ester; Methyl 3-oxolup-20(29)-en-28-oate
Target:  

Drug Intermediate

Research Areas:  

Cancer

Methyl betulonate (Betulonic acid methyl ester) is a triterpenoid. Methyl betulonate inhibits cell growth of eight tumor (including resistant) and two normal fibroblast cell lines with the IC50s >50.0 μM .
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Cat. No.: HY-120075
CAS No.: 1522415-97-9
Purity:  99.83%
Target:  

Apoptosis

Research Areas:  

Cancer

TJ191 is a potent and specific anti-cancer agent that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells. TJ191 has no affects on the proliferation of other cancer cells or normal fibroblasts or immune cells. TJ191 can be used for cancer research .
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Cat. No.: HY-N1031
CAS No.: 958885-86-4
Synonyms: 12-epi-Vitexolide D; Curcucomosin C
Target:  

Bacterial

Research Areas:  

Cancer

Vitexolide E is a diterpenoid compound isolated from the leaves of the Malaysian species Vitex vestita. Vitexolide E shows cytotoxic activities against the HCT-116 cancer cell line and human fetal lung fibroblast MRC5 cell line .
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Cat. No.: HY-123464
CAS No.: 362503-73-9
Purity:  ≥98.0%
Target:  

Ras

Research Areas:  

Cancer

RBC10 is an anti-cancer agent. RBC10 inhibits the binding of Ral to its effector RALBP1. RBC10 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines .
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Cat. No.: HY-118518
CAS No.: 85247-77-4
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease Cancer

Ronipamil is a calcium ion antagonist. Ronipamil increases the specific binding and internalization of human 125I-LDL in human skin fibroblasts (HSF) and the human hepatoma cell line Hep G2 .
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Cat. No.: HY-D1749
CAS No.: 114301-96-1
Target:  

Fluorescent Dye

Research Areas:  

Others

C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.
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Cat. No.: HY-108999
CAS No.: 96389-69-4
Synonyms: BWA770U mesylate
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Crisnatol (BWA770U) mesylate is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol mesylate shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts .
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Cat. No.: HY-172475
Target:  

Liposome

Research Areas:  

Cancer

DSPE-PEG1000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG1000-YIGSR can be used for drug delivery .
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Cat. No.: HY-172476A
Target:  

Liposome

Research Areas:  

Cancer

DSPE-PEG3400-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG3400-YIGSR can be used for drug delivery .
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Cat. No.: HY-161840
Target:  

FGFR

Research Areas:  

Cancer

Antitumor agent-176 (Compound 22), an antitumor agent, can effectively bind to FGF2 and inhibit the activation of fibroblast growth factor receptor (FGFR) in multiple myeloma (MM) cells, exhibiting significant antitumor activity both in vivo and in vitro against MM .
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Cat. No.: HY-167835A
CAS No.: 2824-94-4
Tembetarine chloride is a alkaloid that can be isolated from Tinospora cordifolia that exhibits antibacterial activity. Tembetarine chloride exhibits weak cytotoxicity against mouse fibroblasts (L929) and human embryonic kidney cells (HEK293) with IC50 of 1245.33 μg/mL and 1642.81 μg/mL, respectively .
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Cat. No.: HY-117249
CAS No.: 104958-90-9
Synonyms: AK-2123
Target:  

Apoptosis Caspase

Research Areas:  

Cancer

Sanazole (AK-2123) is a hypoxic cell radiosensitizer. Sanazole enhances radiation-induced DNA strand breaks. In mouse fibroblast tumors, Sanazole increases nuclear condensation and fragmentation, as well as elevates caspase-3 activity, thereby enhancing radiation-induced apoptosis .
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Cat. No.: HY-122006
CAS No.: 384361-79-9
Research Areas:  

Cancer

NPD926 is a small molecule that targets glutathione and induces cancer cell death. NPD926 causes cellular glutathione depletion and subsequent generation of reactive oxygen species (ROS), thereby sensitizing fibroblasts to Xc- system inhibitors. NPD926 is a ROS inducer with anticancer activity. .
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