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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
202 Results for "
outer S5/S6 helices
" in MedChemExpress (MCE) Product Catalog:
Products (202)
202 Results for "outer S5/S6 helices" in MCE Product Catalog:
Cat. No.: HY-P10556
CAS No.: 622402-94-2
Cat. No.: HY-P1403
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Cat. No.: HY-162672
Antibacterial agent 231 (derivative 8) is an antimicrobial agent against multidrug-resistant Helicobacter pylori (H. pylori) with a minimum inhibitory concentration of 0.25–0.5 μg/mL. Antibacterial agent 231 directly targets the protein transposase subunit SecA and the outer membrane protein assembly factor BamD to inhibit the trafficking and assembly of bacterial outer membrane proteins (OMPs). Antibacterial agent 231 can be used to study the effects of antibiotic treatment on intestinal microbial balance .
Cat. No.: HY-124687
CAS No.: 1914944-54-9
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ROMK-IN-32 is a renal outer medullary potassium channel (ROMK) inhibitor with an IC50 of 35 nM. ROMK-IN-32 also inhibits hERG with an IC50 of 22 μM .
Cat. No.: HY-158235
CAS No.: 2966803-96-1
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Tyrosinase-IN-27 (compound 6f) is a tyrosinase (TYR) inhibitor (IC50: 0.88 μM) that statically quenches TYR. Tyrosinase-IN-27 increases the hydrophobicity of the enzyme microenvironment by binding to TYR, reducing the content of α-helices in the enzyme and changing its secondary structure. Tyrosinase-IN-27 can be used in the food industry to effectively inhibit the browning of lotus root slices. .
Cat. No.: HY-144387
CAS No.: 3033367-64-2
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ient S. Tm and hyperpermeable Escherichia coli. The potencies against WT strains of E. coli, Acinetobacter baumannii, and Burkholderia cenocepacia are also improved considerably (up to >128-fold) with the outer-membrane permeabi
Cat. No.: HY-W839203
CAS No.: 37070-48-7
Synonyms: 1,2-Didocosanoyl-sn-glycero-3-phosphocholine; PC(22:0/22:0)
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22:0 PC (1,2-Didocosanoyl-sn-glycero-3-phosphocholine), a type of phosphatidylcholine, functions as a lung surfactant and is characterized as an amphipathic molecule predominantly found in the outer leaflets of biological membrane bilayers.
Cat. No.: HY-162555
CAS No.: 2254333-97-4
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BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor. BMS-986308 is selective for ROMK over hERG. BMS-986308 can be used for heart failure research .
Cat. No.: HY-P1632A
Cat. No.: HY-161413
CAS No.: 1211465-32-5
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Antibacterial agent 204 (Compd P2-56-3) possesses potentiated Rifampin (RIF) activity against Acinetobacter baumannii and Klebsiella pneumoniae. Antibacterial agent 204 (Compd P2-56-3) disrupts the outer membrane of A. baumannii. T .
Cat. No.: HY-149810
CAS No.: 2890177-90-7
AcrB-IN-2 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. AcrB-IN-22 inhibits Nile Red (a known substrate of AcrB) efflux.AcrB-IN-2 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
Cat. No.: HY-172348
CAS No.: 443894-71-1
BRD-9327 is an inhibitor of EfpA. BRD-9327 binds in the outer vestibule without complete blockade of the substrate path to the outside, suggesting its possible inhibition of the movement necessary for alternate access of the transporter. BRD-9327 can be used for anti-tuberculosis study .
Cat. No.: HY-149811
CAS No.: 2890177-94-1
Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
Cat. No.: HY-144279
CAS No.: 2918334-61-7
MsbA-IN-1 is a highly potent MsbA inhibitor with IC50 of 4 nM. MsbA-IN-1 has activity against wild-type E. coli with MIC of 79 μM. MsbA-IN-1 possesses sufficient permeability across the fully intact outer membrane of Gram-negative bacteria to inhibit MsbA .
Cat. No.: HY-152022S
CAS No.: 2692624-26-1
Synonyms: N-(32-lioleoyloxy-dotiacotaoyl)-sphigosie-d9
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EOS (d18:1/32:0/18:2)-d9 is the deuterium labeled EOS (d18:1/32:1/18:2) (HY-139393). EOS (d18:1/32:1/18:2) is a kind ceramide in the outer epidermis .
Cat. No.: HY-B0359R
CAS No.: 73151-29-8
Synonyms: REC 15-1476 (Standard)
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Fenticonazole (Nitrate) (Standard) is the analytical standard of Fenticonazole (Nitrate). This product is intended for research and analytical applications. Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
