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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
293 Results for "
pyruvate
" in MedChemExpress (MCE) Product Catalog:
Products (293)
293 Results for "pyruvate" in MCE Product Catalog:
Cat. No.: HY-19702
CAS No.: 1628428-01-2
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PKR activator 3 (Compound 160) is a red blood cell pyruvate kinase (PKR) activator. PKR activator 3 can be used in the research of diseases related to PKR function, such as pyruvate kinase deficiency (PKD) .
Cat. No.: HY-161679S
Cat. No.: HY-161680
CAS No.: 2369048-06-4
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Pyruvate Carboxylase-IN-4 (Compd 8V) is a potent and competitive Pyruvate Carboxylase inhibitor with an IC50 of 4.3 μM .
Cat. No.: HY-119874
CAS No.: 23444-65-7
Category:
Quinones Ohwia caudata (Thunberg) H. Ohashi Monophenols Phenols Plants Compositae Extract Disease Research Fields Inflammation/Immunology Naphthalene Quinones
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OBA-09, a simple ester of pyruvate and salicylic acid, is potent multi-modal neuroprotectant. OBA-09 has anti-oxidative and anti-inflammatory effects .
Cat. No.: HY-150287B
Synonyms: ITS-A
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Alanine dehydrogenase, expressed in E. coli is a microbial enzyme that catalyzes a reversible conversion of L-alanine to pyruvate .
Cat. No.: HY-153354
CAS No.: 2283420-05-1
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PKR activator 4 (example 7A) is a potent pyruvate kinase R (PKR) activator. PKR activator 4 has the potential for the research of blood disorders .
Cat. No.: HY-W754527
CAS No.: 554-44-9
Synonyms: Allithiamin
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Cat. No.: HY-168446
CAS No.: 3057531-75-3
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PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor that has antifungal activity, with an EC50 of 0.21 μg/mL for R. solani .
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Ethyl pyruvate (Standard) is the analytical standard of Ethyl pyruvate. This product is intended for research and analytical applications. Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Ethyl pyruvate is an HMGB1 release inhibitor. Ethyl pyruvate can induce apoptosis by autophagy. Ethyl pyruvate has anti-inflammatory, antioxidant and anti-tumor activity. Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's disease .
Cat. No.: HY-Y1362S
CAS No.: 66966-38-9
Cat. No.: HY-P3170
CAS No.: 61461-61-8
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β-alanine-pyruvate transaminase is an enzyme. Dihydrouracil and dihydrothymine, as nitrogen sources, increase the activity of β-alanine-pyruvate transaminase in cultured B. cepacia cells. The activity of β-alanine-pyruvate transaminase can be measured by tracking the release of L-α-alanine during the reaction .
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Pyruvate oxidase, Aerococcus viridans (PoxB) is a thiamine pyrophosphate-dependent oxidase that catalyzes the oxidative decarboxylation of pyruvate to produce acetyl phosphate, carbon dioxide, and water. Pyruvate oxidase, Aerococcus viridans is an important enzyme in bacterial metabolism and can enhance ATP production. Additionally, Pyruvate oxidase, Aerococcus viridans can be used for the determination of aspartate aminotransferase and alanine aminotransferase activities .
Cat. No.: HY-12689C
CAS No.: 2559738-69-9
Synonyms: AG-348 hydrochloride
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Mitapivat (AG-348) hydrochloride is an orally active and selective allosteric pyruvate kinase R (PK-R) activator. Mitapivat hydrochloride accelerates the reaction of PK-R catalyzing the conversion of phosphoenolpyruvate to pyruvate, thereby promoting the glycolytic pathway, increasing the production of adenosine triphosphate (ATP) in red blood cells, and reducing the level of 2,3-diphosphoglycerate (2,3-DPG). Mitapivat hydrochloride is promising for research of pyruvate kinase deficiency and other anemia-related diseases .
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Phenylpyruvate tautomerase catalyzes the interconversion of the enol and keto isomers of phenylpyruvate and (p-hydroxyphenyl)pyruvate .
Cat. No.: HY-12689B
CAS No.: 2329710-91-8
Synonyms: AG-348 hemisulfate
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Mitapivat hemisulfate is an orally active pyruvate kinase allosteric activator. Mitapivat hemisulfate increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat hemisulfate can be used in study of PK deficiency .
Cat. No.: HY-159095
CAS No.: 2761226-35-9
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PKR activator 5 (Compound 18) is an activator for pyruvate kinase R (PKR) with an AC50 of 28 nM .
Cat. No.: HY-12689A
CAS No.: 2151847-10-6
Synonyms: AG-348 hemisulfate sesquihydrate
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Mitapivat hemisulfate sesquihydrate (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency .
Cat. No.: HY-162071
CAS No.: 904457-46-1
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PKM2-IN-5 (Compound G1) is an inhibitor for pyruvate kinase M2 (PKM2), with IC50 >70 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
