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Cat. No.: HY-Y1362R

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Ethyl pyruvate (Standard)

Ethyl pyruvate (Standard) is the analytical standard of Ethyl pyruvate. This product is intended for research and analytical applications. Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate. Ethyl pyruvate is an HMGB1 release inhibitor. Ethyl pyruvate can induce apoptosis by autophagy. Ethyl pyruvate has anti-inflammatory, antioxidant and anti-tumor activity. Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

For research use only. We do not sell to patients.

CAS No.: 617-35-6
Formula: C₅H₈O₃
Molecular Weight:116.12

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ethyl pyruvate (Standard) Chemical Structure

CAS No.: 617-35-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
- Information
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
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Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 617-35-6
Molecular Weight 116.12
Formula C₅H₈O₃
SMILES

CC(C(OCC)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Fink MP. Ethyl pyruvate: a novel anti-inflammatory agent. J Intern Med. 2007 Apr;261(4):349-62. [Content Brief]

[2]. Olcum M, Tufekci KU, Durur DY, et al. Ethyl Pyruvate Attenuates Microglial NLRP3 Inflammasome Activation via Inhibition of HMGB1/NF-κB/miR-223 Signaling. Antioxidants (Basel). 2021;10(5):745. [Content Brief]

[3]. Liang X, et al. Ethyl pyruvate administration inhibits hepatic tumor growth. J Leukoc Biol. 2009 Sep;86(3):599-607. [Content Brief]

[4]. Qiu X, et al. Ethyl pyruvate confers protection against endotoxemia and sepsis by inhibiting caspase-11-dependent cell pyroptosis. Int Immunopharmacol. 2020 Jan;78:106016. [Content Brief]

[5]. Lee J, et al. Protective effects of ethyl pyruvate treatment on paraquat-intoxicated rats. Hum Exp Toxicol. 2008 Jan;27(1):49-54.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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