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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
281 Results for "
variants
" in MedChemExpress (MCE) Product Catalog:
Products (281)
281 Results for "variants" in MCE Product Catalog:
Referencia número: HY-P2319A
No. CAS: 1262750-80-0
Áreas de investigación:
Referencia número: HY-P1771A
Target:
Áreas de investigación:
Referencia número: HY-P2258
Target:
Áreas de investigación:
Target:
Áreas de investigación:
Referencia número: HY-P99633
No. CAS: 2342597-81-1
Synonyms: BGB-A333
Target:
Áreas de investigación:
Referencia número: HY-P991697
No. CAS: 3038720-27-0
Target:
Áreas de investigación:
Referencia número: HY-118992
No. CAS: 12704-90-4
Synonyms: X 5108; Goldinomycin
Target:
Referencia número: HY-132581E
Synonyms: Scrambled BIIB078; Scrambled IONIS-C9Rx
Target:
Áreas de investigación:
Scrambled Tadnersen is the Negative Control of Tadnersen sodium (HY-132581A). Tadnersen sodium, an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion .
Referencia número: HY-P99362
No. CAS: 1092658-06-4
Synonyms: Anti-MUC5AC Reference Antibody (ensituximab); NEO-102
Synonyms: A1AT modulator 1
Target:
Áreas de investigación:
GSK716 (A1AT modulator 1) is an orally active Z α1-antitrypsin (Z-A1AT) inhibitor with a pIC50 of 8.3. GSK716 binds a cryptic Z α1-antitrypsin pocket, stabilizes monomeric folding intermediates, blocks polymerization, and increases monomer secretion. GSK716 acts on select sensitive α1-antitrypsin variants but fails to affect resistant variants. GSK716 can be used for the research of α1-antitrypsin deficiency and α1-antitrypsin deficiency-associated liver disease .
Referencia número: HY-157512
No. CAS: 2413035-43-3
Target:
Áreas de investigación:
SJF-0661 is a variant of the von Hippel-Lindau (VHL) protein ligand with no targeted degradation ability and can be used as a control reagent for the VHL ubiquitin ligase ligand. SJF-0661 is a variant obtained by inverting the stereocenter of the key hydroxyproline group in the VHL ligand .
Referencia número: HY-P991678
No. CAS: 2996895-52-2
Synonyms: XENP-27564; XMAB-27564
Target:
Áreas de investigación:
Referencia número: HY-155100
No. CAS: 2767011-00-5
Target:
Áreas de investigación:
BI 7446 is a cyclic dinucleotide (CDN)-based potent and selective stimulator of interferon genes (STING) agonist. BI 7446 can activate all five STING variants in cells and induce tumor-specific immune-mediated tumor rejection. BI 7446 can be used for immuno-oncology research .
Referencia número: HY-177650A
Synonyms: ALN-TTRsc04 sodium
Target:
Áreas de investigación:
Nucresiran sodium is a siRNA that inhibits hepatic synthesis of both wild-type and variant TTR mRNA.
Referencia número: HY-15380
No. CAS: 185220-03-5
Target:
Áreas de investigación:
PNU-142721 is a reverse transcriptase inhibitor and PXR agonist that effectively inhibits various type I HIV variants .
Referencia número: HY-B0648S
No. CAS: 162462-69-3
Synonyms: 17α-Hydroxy-6α-methylprogesterone-d3; U8840-d3
Referencia número: HY-132581C
Synonyms: Scrambled BIIB078 sodium; Scrambled IONIS-C9Rx sodium
Target:
Áreas de investigación:
Scrambled Tadnersen sodium is the Negative Control of Tadnersen sodium (HY-132581A). Tadnersen sodium, an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion .
Referencia número: HY-P2319
No. CAS: 153316-01-9
Áreas de investigación:
Referencia número: HY-128762
No. CAS: 2415152-07-5
Target:
Áreas de investigación:
ML256 is a covalent lipoprotein-associated phospholipase A2 (Lp-PLA2 inhibitor. ML256 can be used for the study of neoplasms harboring a constitutively active variant of one or both of KRAS or HRAS .
Referencia número: HY-144391
No. CAS: 2763387-69-3
Target:
Áreas de investigación:
Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor (IC50=0.12 mM). Chitin synthase inhibitor 1 has potent antifungal activity against drug-resistant fungi variants .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
