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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
124 Results for "
Estrogen Receptor Modulator
" in MedChemExpress (MCE) Product Catalog:
Products (124)
124 Results for "Estrogen Receptor Modulator" in MCE Product Catalog:
Cat. No.: HY-135582S1
Cat. No.: HY-116896R
CAS No.: 63676-25-5
Target:
Research Areas:
LY117018 (Standard) is the analytical standard of LY117018. This product is intended for research and analytical applications. LY117018, a Raloxifene analog, is a selective estrogen receptor modulator. LY117018 exerts antiproliferative effects on breast cancer cell lines .
Cat. No.: HY-135582S
CAS No.: 1279033-52-1
Cat. No.: HY-121149B
CAS No.: 165813-01-4
Synonyms: (E/Z)-3-Hydroxytamoxifen
Target:
Research Areas:
(E/Z)-Droloxifene is a mixture of (E)-droloxifene (a selective estrogen receptor modulator) and (Z)-droloxifene. (E)-Droloxifene binds to the estrogen receptor (ER) with an IC50 value of 24 nM in rabbit uterine homogenates. (E)-Droloxifene increases uterine weight in immature rats, and reduces estradiol-induced increases in uterine weight in juvenile rats. (E)-Droloxifene also inhibits 17β-estradiol-stimulated growth of MCF-7, ZR-75-1, and T47D human breast cancer cells. (Z)-Droloxifene binds weakly to ER and has no estrogenic or antiestrogenic activity .
Cat. No.: HY-15731S1
CAS No.: 2734920-42-2
Cat. No.: HY-123664
CAS No.: 68307-81-3
Synonyms: LY133314
Target:
Research Areas:
Trioxifene mesylate (LY133314) is an orally active and selective estrogen receptor (ER) modulator with human ERα IC50 of 203.49 nM and Ki of 20.84 nM. Trioxifene mesylate binds estradiol receptors, inhibits ERα-mediated gene expression, reduces circulating gonadotrophin levels. Trioxifene mesylate can be used for the research of advanced breast cancer and androgen-independent, metastatic prostatic adenocarcinoma .
Cat. No.: HY-B0005AS
Synonyms: Z-Toremifene-d6; NK 622-d6 free base; FC-1157a-d6 free base
Cat. No.: HY-W011100R
CAS No.: 2624-43-3
Research Areas:
Cyclofenil (Standard) is the analytical standard of Cyclofenil. This product is intended for research and analytical applications. Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50 of 1.62 μM. Cyclofenil has anti-dengue-virus activity .
Cat. No.: HY-79576S2
Synonyms: Oestrone methyl ether-13C6; 3-O-Methylestrone-13C6
Cat. No.: HY-B0005S1
Synonyms: Z-Toremifene-d6 hydrochloride; NK 622-d6 hydrochloride; FC-1157a-d6 hydrochloride
Cat. No.: HY-B0005S
CAS No.: 1246833-71-5
Cat. No.: HY-13757AS1
CAS No.: 508201-30-7
Synonyms: ICI 47699-d3; (Z)-Tamoxifen-d3; trans-Tamoxifen-d3
Cat. No.: HY-B0005R
CAS No.: 89778-27-8
Synonyms: Z-Toremifene citrate (Standard); NK 622 (Standard); FC-1157a (Standard)
Toremifene (citrate) (Standard) is the analytical standard of Toremifene (citrate). This product is intended for research and analytical applications. Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 µM and 2.6 µM, respectively .
Cat. No.: HY-W778408
CAS No.: 1346606-38-9
Synonyms: ICI 47699-13C6; (Z)-Tamoxifen-13C6; trans-Tamoxifen-13C6
Cat. No.: HY-U00178R
CAS No.: 116057-75-1
Synonyms: CB7432 (Standard)
Research Areas:
Idoxifene (CB7432) is a novel tissue-specific selective estrogen receptor modulator (SERM).
Cat. No.: HY-Z0833
CAS No.: 1174289-22-5
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Bazedoxifene N-Oxide is the oxidative degradation product of selective estrogen receptor modulator (SERM) Bazedoxifene .
Cat. No.: HY-16470
CAS No.: 229634-98-4
Synonyms: TAS-108
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Research Areas:
SR 16234 (TAS-108) is a selective estrogen receptor modulator. SR 16234 is promising for research of pain symptoms associated with endometriosis .
Cat. No.: HY-W744272
Cat. No.: HY-182498
CAS No.: 1308808-22-1
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Research Areas:
(Z)-Norendoxifen is an aromatase inhibitor and estrogen receptor modulator. The IC50 value of (Z)-Norendoxifen against aromatase is 102 nM. The EC50 values of (Z)-Norendoxifen for ER-α and ER-β are 27.0 nM and 35.2 nM, respectively. (Z)-Norendoxifen can be used in breast cancer research .
Cat. No.: HY-135529
CAS No.: 63619-84-1
Synonyms: LY133314 free base
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Research Areas:
Trioxifene (LY133314 free base) is an orally active and selective estrogen receptor (ER) modulator with human ERα IC50 of 203.49 nM and Ki of 20.84 nM. Trioxifene binds estradiol receptors, inhibits ERα-mediated gene expression, reduces circulating gonadotrophin levels. Trioxifene can be used for the research of advanced breast cancer and androgen-independent, metastatic prostatic adenocarcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
