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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
198 Results for "
H2O2
" in MedChemExpress (MCE) Product Catalog:
Products (198)
198 Results for "H2O2" in MCE Product Catalog:
Cat. No.: HY-155022
CAS No.: 2937454-22-1
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AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. AChE-IN-30 has neuroprotective activity, and inhibits H2O2-induced apoptosis by suppressing intracellular ROS accumulation. AChE-IN-30 can be used for research of Alzheimer's disease .
Cat. No.: HY-P5317A
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Cat. No.: HY-N10277
Category:
Target:
Cat. No.: HY-146168
CAS No.: 1012860-13-7
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Nrf2 activator-5 (compound 1) is a potent Nrf2 activator that can attenuate H2O2-induced oxidative stress and LPS-stimulated inflammation in BV-2 microglial cells. Nrf2 activator-5 exhibits antioxidant and anti-inflammatory activities .
Cat. No.: HY-168068
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Res-Glu3 is the derivative of Resveratrol (HY-16561). Res-Glu3 mitigates the ROS accumulation, and exhibits neuroprotective efficacy against H2O2-caused cellular damage in PC12. Res-Glu3 exhibits antioxidant activity in rats ischemia reperfusion models .
Cat. No.: HY-114886
CAS No.: 351978-83-1
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IGP-5 is a mitochondrial sn-Glycerol 3-phosphate Dehydrogenase (mGPDH) inhibitor with the IC50 of 0.7 μM aganist mGPDH H2O2 production . IGP-5 can be used for study of energy metabolism .
Cat. No.: HY-N2203
CAS No.: 59282-55-2
Category:
Plant Flavonoids Flavones Other Diseases Phenols Polyphenols Other Families Extract Disease Research Fields
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Cat. No.: HY-N10384
CAS No.: 460345-17-9
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AChE-IN-17 (compound 1) is a potent AChE inhibitor with an IC50 value of 28.98 μM. AChE-IN-17 can significantly prevent H2O2-induced PC12 cell death, exhibiting excellent neuroprotective effect. AChE-IN-17 can be used for researching neurodegenerative diseases (NDs) .
Cat. No.: HY-N6595
CAS No.: 97653-92-4
Category:
Human Gut Microbiota Metabolites Terpenoids Diterpenoids Microorganism Endogenous metabolite
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Cat. No.: HY-B0019
CAS No.: 123040-69-7
Synonyms: (Rac)-SENS-401 free base
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Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems .
Cat. No.: HY-B1776AR
CAS No.: 334-50-9
Cat. No.: HY-120485
CAS No.: 128232-14-4
Synonyms: IRFI-016
Research Areas:
Raxofelast (IRFI-016) is an antioxidant agent in various models of ischemia-reperfusion injury. Raxofelast has antiproliferative activity in H2O2-stimulated rat aortic smooth muscle cells. Raxofelast attenuates the activation of mitogen-activating protein kinase (MAPK), ERK kinase 1, 2 (MEK1,2) and protein kinase C (PKC) without affecting Ras expression .
Cat. No.: HY-157437
CAS No.: 3038810-09-9
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AChE/BChE-IN-16 (compound C7) is a potent cholinesterase (ChE) inhibitor with IC50s of 30 nM and 48 nM for human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBChE), respectively. AChE/BChE-IN-16 exhibits a remarkable capacity to safeguard PC12 cells against H2O2-induced apoptosis and effectively suppresses the production of reactive oxygen species (ROS) .
Cat. No.: HY-121174
CAS No.: 39723-40-5
Synonyms: Catharticin
Cat. No.: HY-168031
CAS No.: 2756368-79-1
Target:
Histamine Receptor Calcium Channel Cholinesterase (ChE) Reactive Oxygen Species (ROS) Amyloid-β
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AChE/BChE-IN-21 is a histamine H3 receptor antagonist, calcium channel blocker, and acetylcholinesterase inhibitor. AChE/BChE-IN-21 exhibits neuroprotective activity against H2O2 and Aβ1-40, and can restore cognitive function in AD mice .
Cat. No.: HY-101859R
CAS No.: 1404091-23-1
Synonyms: Nuc-H2O2 Probe (Standard)
Cat. No.: HY-186316
CAS No.: 2769053-56-5
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Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
KDS12025 is a blood-brain barrier-permeable, orally active H2O2-decomposing peroxidase enhancer. KDS12025 enhances the H2O2-decomposing pseudoperoxidase activity of Hb without altering oxygen transport function, and reduces intracellular H2O2 load. KDS12025 reduces abnormal H2O2 levels and inhibits the production of COL1. KDS12025 restores cerebral blood flow, maintains neuronal excitability, membrane properties, synaptic connections and corticospinal tract fibers, reduces cerebral edema and exerts neuroprotective effects. KDS12025 improves motor function and overall neurological function. KDS12025 can be used in the research of ischemic stroke, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, aging-related neurodegenerative diseases and rheumatoid arthritis .
Cat. No.: HY-180260
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Anticancer agent 289 is a H2O2-responsive anticancer prodrug. Anticancer agent 289 exhibits H2O2-inducible DNA-alkylating activity, selectively inhibits the proliferation of high ROS-expressing cancer cells over nonmalignant cells, markedly suppresses tumor growth without observable toxicity in vivo. Anticancer agent 289 can be used for triple-negative breast cancer (TNBC) research .
Cat. No.: HY-N17964
CAS No.: 1417579-26-0
Category:
Plant Terpenoids Aralia elata (Miq.) Seem. Extract Pentacyclic Triterpenoids Araliaceae Extract
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Cat. No.: HY-D2963
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
