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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
192 Results for "
P2Y Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (192)
192 Results for "P2Y Receptor" in MCE Product Catalog:
Cat. No.: HY-107752A
CAS No.: 851191-73-6
Target:
Research Areas:
2-(Phenylethynyl)-ATP (ammonium) is a selective and potent GPR17 agonist with an EC50 of 35 pM. 2-(Phenylethynyl)-ATP (ammonium) also shows weak activation of P2Y Receptor. 2-(Phenylethynyl)-ATP (ammonium) can be used for the research of neurological disease .
Cat. No.: HY-P81901A
Synonyms: P2Y15; Alpha-ketoglutarate Receptor 1; G-protein coupled Receptor 80; G-protein coupled Receptor 99; P2Y purinoceptor 15
Cat. No.: HY-110265
CAS No.: 1279829-64-9
Target:
Research Areas:
SAR216471 hydrochloride is a P2Y12 receptor antagonist. SAR216471 hydrochloride has antiplatelet and antithrombotic activities in vivo .
Cat. No.: HY-108662R
CAS No.: 56583-49-4
Synonyms: 2,2'-Pyridylisatogen tosylate (Standard)
Target:
Research Areas:
PIT (Standard) is the analytical standard of PIT (HY-108662). This product is intended for research and analytical applications. PIT (2,2'-Pyridylisatogen tosylate) is a selective and non-competitive antagonist of P2Y1 receptor with an IC50 value of 0.14 μM for human P2Y1 receptor. PIT antagonizes P2Y1 receptor signaling without affecting nucleotide binding. PIT is an irreversible antagonist of responses to ATP at metabotropic purinoceptors (of the P2Y family) in some smooth muscles. PIT can be used for the research of chronic bronchitis and asthma .
Cat. No.: HY-113359AS1
Synonyms: UDP-13C9 dilithium
Cat. No.: HY-172181
Target:
Research Areas:
NSC380324 is a P2Y12 receptor antagonist, possessing antiplatelet activity, and can be utilized in research on atherosclerotic cardiovascular diseases .
Cat. No.: HY-168139
CAS No.: 2801624-14-4
Target:
Research Areas:
MRS4865 (compund 7a) is a chimera of a P2Y14 receptor antagonist and a UDP-glucose agonist that protects against neuropathic pain .
Cat. No.: HY-W412336
CAS No.: 6397-02-0
Research Areas:
Acid blue 129 is an acidic dye and highly selective antagonist at the P2Y-receptor of the guinea pig taenia coli. Acid blue 129 does not show any effect at the P2X-receptor of the rat vas deferens. Acid blue 129 can be used for the dyeing of cotton, wool, silk, nylon, paper and leather .
Cat. No.: HY-124987
CAS No.: 2225834-49-9
Target:
Research Areas:
MRS4458 is a P2Y14 receptor antagonist with anti-inflammatory activity. MRS4458 mediates inflammatory activity by activating the motility of neutrophils. The design of MRS4458 is based on the interaction with the P2Y14 receptor and optimized by molecular dynamic simulation. MRS4458 performs well in terms of shape and complementarity with the receptor. The prediction that the 5-phenyl group of MRS4458 is substituted with thiophene is generally consistent with empirical results. The biological activity of MRS4458 was verified by fluorescence assay, showing its potent antagonistic effect .
Cat. No.: HY-172417
CAS No.: 1416696-44-0
Synonyms: 2-Oxoclopidogrel
Target:
Research Areas:
Becondogrel (2-Oxoclopidogrel) is the metabolite of Clopidogrel (HY-15283). Becondogrel irreversibly inhibits P2Y12 receptor, thereby inhibiting platelet aggregation and thrombosis .
Cat. No.: HY-P87410A
Synonyms: GPR86, GPR94, FKSG77, P2RY13, P2Y purinoceptor 13, P2Y13, G-protein coupled Receptor 86, G-protein coupled Receptor 94
Cat. No.: HY-10064R
CAS No.: 274693-27-5
Synonyms: AZD6140 (Standard); AR-C 126532XX (Standard)
Target:
Research Areas:
Ticagrelor (Standard) is the analytical standard of Ticagrelor. This product is intended for research and analytical applications. Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation.
Cat. No.: HY-P87577
Synonyms: GPR80, GPR99, P2RY15, P2Y15, OXGR1, 2-oxoglutarate Receptor 1, Alpha-ketoglutarate Receptor 1, G-protein coupled Receptor 80, G-protein coupled Receptor 99, P2Y purinoceptor 15, P2Y-like GPCR, P2Y-like nucleotide Receptor
Cat. No.: HY-181738
Target:
Research Areas:
GPR17 agonist 2 (compound 10) is a human GPR17 agonist and selective P2Y receptor non-activator.GPR17 agonist 2 modulates intracellular cAMP levels through functional activation of its target receptor.GPR17 agonist 2 can be used for the research of multiple sclerosis, cerebral ischemia, traumatic brain injury, spinal cord injury .
Cat. No.: HY-P87437A
Synonyms: P2RU1, P2RY2, P2Y purinoceptor 2, P2Y2, ATP Receptor, P2U purinoceptor 1, P2U Receptor 1, Purinergic Receptor, P2U1
Cat. No.: HY-P703107
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LTB4R; P2Y Purinoceptor 7; Prev. CMKRL1; LTB4-R1; Prev. GPR16; BLT1; Prev. P2RY7; Purinergic Receptor P2Y, G-Protein Coupled, 7; BLTR; G Protein-Coupled Receptor 16; P2Y7; G-Protein Coupled Receptor 16; LTB4R1; Chemokine Receptor-Like 1; Chemoattractant R
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-115736B
CAS No.: 3056945-74-2
Synonyms: 5'-XTP lithium
Target:
Research Areas:
Xanthosine-5'-triphosphate (5'-XTP) lithium is a purine nucleotide that stimulates Adenylate Cyclase to induce Cyclic AMP (cAMP) (HY-B1511) biosynthesis, binds to the AL1 allosteric site of the D137N-SAMHD1 mutant to activate dNTP triphosphohydrolase activity, and stimulates P2Y/P2U purinergic receptor-coupled phosphoinositide-specific phospholipase C with Michaelis-Menten kinetics. Xanthosine-5'-triphosphate lithium can be used for HIV-1 research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
