2-(Phenylethynyl)-ATP ammonium
2-(Phenylethynyl)-ATP (ammonium) is a selective and potent GPR17 agonist with an EC50 of 35 pM. 2-(Phenylethynyl)-ATP (ammonium) also shows weak activation of P2Y Receptor. 2-(Phenylethynyl)-ATP (ammonium) can be used for the research of neurological disease.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 851191-73-6
- 分子式: C18H32N9O13P3
- 分子量:675.42
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
P2Y Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
[1]|
GPR17 35 pM (EC50) |
P2Y12 Receptor 1348 nM (EC50) |
P2Y13 Receptor 3388 nM (EC50) |
P2Y14 Receptor 178 nM (EC50) |
体外実験
2-(Phenylethynyl)-ATP (ammonium) (Compound 1) potently activates human GPR17 in transiently transfected HEK293 L9-2 cells, with an EC50 of 35 ± 3 pM[1].
2-(Phenylethynyl)-ATP (ammonium) activates human GPR17 in the [35S]GTPγS binding assay with an EC50 of 36 pM[1].
2-(Phenylethynyl)-ATP (ammonium) activates human P2Y12, P2Y13, and P2Y14 receptors in transiently transfected HEK293 L9-2 cells, with EC50 values of 178-3388 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 851191-73-6
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分子量 675.42
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分子式 C18H32N9O13P3
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SMILES
O=P(OP(OP([O-])([O-])=O)([O-])=O)([O-])OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C(N)N=C(C#CC4=CC=CC=C4)N=C32)O1.[NH4+].[NH4+].[NH4+].[NH4+]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
2-(Phenylethynyl)-ATP ammonium 関連分類
HY-107752A 関連分類
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