Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
107 Results for "
Solid-phase synthesis
" in MedChemExpress (MCE) Product Catalog:
Products (107)
107 Results for "Solid-phase synthesis" in MCE Product Catalog:
Cat. No.: HY-185906
Target:
Research Areas:
DBCO Phosphoramidite is a phosphoramidite reagent containing a dibenzocyclooctyne (DBCO) moiety, which can introduce a strain-promoted alkyne group for copper-free click chemistry into DNA strands during solid-phase oligonucleotide synthesis. DBCO Phosphoramidite is applicable to studies related to oligonucleotide modification, copper-free click conjugation, and functionalized DNA nanomaterials .
Cat. No.: HY-P11685
CAS No.: 2245800-85-3
Target:
Research Areas:
Cat. No.: HY-P11695
CAS No.: 2988301-08-0
Target:
Research Areas:
Cat. No.: HY-104004R
CAS No.: 120173-57-1
Synonyms: Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH (Standard); Fmoc-Ser[GalNAc(Ac)3-α-D]-OH (Standard); Fmoc-Ser(Ac3AcNH-α-Gal)-OH (Standard)
Research Areas:
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Standard) is the analytical standard of Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (HY-104004). This product is intended for research and analytical applications. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH (Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH) is a protected glycosylated amino acid and Tn antigen. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH serves as a building block in the solid-phase synthesis of Tn-based cancer vaccine constructs. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH supports solid-phase peptide synthesis .
Cat. No.: HY-P11683
Target:
Research Areas:
Cat. No.: HY-P11681
CAS No.: 163081-03-6
Target:
Research Areas:
Cat. No.: HY-P11691
CAS No.: 2101661-88-3
Target:
Research Areas:
Cat. No.: HY-W1061415
CAS No.: 2378004-17-0
Research Areas:
5'-Aqp 593 Phosphoramidite hexafluorophosphate is a cyanin-based fluorescent phosphoridamide monomer suitable for solid-phase oligonucleotide synthesis. It allows for site-specific labeling of the 5' end of DNA and RNA with the AquaPhluor 593 fluorescent dye. 5'-Aqp 593 Phosphoramidite hexafluorophosphate can be used to synthesize 5'-terminal fluorescently labeled oligonucleotides for various fluorescence experiments.
Cat. No.: HY-185911
Amino-modifier C6 dC(N-Bz) Phosphoramidite is a modified deoxycytidine synthesis monomer featuring an amino group attached via a six-carbon spacer arm. Amino-modifier C6 dC(N-Bz) Phosphoramidite allows for the site-specific incorporation of an amino group during the solid-phase synthesis of DNA oligonucleotides, enabling conjugation with functional moieties—such as fluorescent groups, peptides, or biotin—to produce functional nucleic acid probes.
Cat. No.: HY-183383
CAS No.: 144303-74-2
Synonyms: 4-Thio-DU CEP
Target:
Research Areas:
4-Thio-dU CE phosphoramidite (4-Thio-DU CEP) is a special modified nucleotide unit of thymine/uracil structure, used in solid-phase oligonucleotide synthesis to introduce the protected 4-sulfur carbonyl group into the DNA or RNA chain. 4-Thio-dU CE phosphoramidite is mainly used for photocrosslinking, photophilic labeling, nucleic acid structure research, and site-specific functionalization through sulfur atoms after synthesis.
Cat. No.: HY-188032
Target:
Research Areas:
2',3'-ddG(N-dmf) Phosphoramidite is a 2',3'-double deoxy-alkylamino monomer of guanine. The N²-amino group of the guanine outer ring is protected by dimethylmethylammonium. Compared with the traditional isobutyryl group, it can be deprotection under milder and faster conditions and reduce purine removal, and is specifically used to introduce G-type termination sites at the 3' end during solid-phase synthesis.
Cat. No.: HY-P11684
CAS No.: 172405-61-7
Target:
Research Areas:
Cat. No.: HY-185901
Cat. No.: HY-P11688
Target:
Research Areas:
Cat. No.: HY-138586S
Target:
Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Phosphoramidites
Research Areas:
DMT-dC(ac) Phosphoramidite- 13C9, 15N3 is the 13C, 15N-labeled DMT-dC(ac) Phosphoramidite (HY-138586). DMT-dC (ac) Phosphoramidite is a phosphoramidite used for incorporating N4-acetyl deoxycytidine into oligonucleotides. DMT-dC (ac) Phosphoramidite enables the synthesis of modified DNA sequences via standard solid-phase chemistry. DMT-dC (ac) Phosphoramidite is used in research on oligonucleotide synthesis .
Cat. No.: HY-185910
Target:
Research Areas:
Palmitamido-C7 CE-Phosphoramidite is a long-chain esterified phosphoramidite monomer used for solid-phase oligonucleotide synthesis. Palmitamido-C7 CE-Phosphoramidite is formed by linking palmitamido to the active end of 2-cyanoethyl phosphoramidite via a C7 alkyl spacer arm. Palmitamido-C7 CE-Phosphoramidite can be used as a building block for nucleic acid chemical modification to synthesize ester-coupled oligonucleotides.
Cat. No.: HY-185907
CAS No.: 1772522-17-4
Target:
Research Areas:
5'-Octyltocopherol C8 CE Phosphoramidite is a tocopherol-based phosphoramidite modification monomer for solid-phase oligonucleotide synthesis, which can introduce an octyltocopherol modification group with a C8 spacer arm at the 5'-end of oligonucleotides. 5'-Octyltocopherol C8 CE Phosphoramidite can be used to prepare DNA or RNA with hydrophobic tocopherol terminal modifications. 5'-Octyltocopherol C8 CE Phosphoramidite is applicable to studies related to oligonucleotide chemical synthesis, nucleic acid hydrophobic modification, and nucleic acid conjugate construction.
Cat. No.: HY-W1119956
CAS No.: 3103531-71-8
Synonyms: 5'(E)-VP-2'-OMe-iBu-G
Phosphoramidite
Research Areas:
5'-(E)-VPG Phosphoramidite (5'(E)-VP-2'-OMe-iBu-GPhosphoramidite) is a structurally modified phosphoramidite reagent used to synthesize biologically stable oligonucleotides. 5'-(E)-VPG Phosphoramidite (POM) carries a VP protecting group and can be coupled to the target oligonucleotide at the 5' end via solid-phase synthesis. The modified oligonucleotide is then constructed through oxidation and deprotection steps. 5'-(E)-VPG Phosphoramidite is suitable for RNAi and viral replication research .
Cat. No.: HY-W1061747
Target:
Research Areas:
endo-BCN-PEG3 Phosphoramidite is a nucleic acid phosphoramidite modifier containing an endo-bicyclononyne (BCN) group and a PEG3 spacer, enabling site-specific incorporation of endo-BCN-PEG3 into DNA or RNA during solid-phase oligonucleotide synthesis. endo-BCN-PEG3 Phosphoramidite introduces a BCN group that can undergo copper-free strain-promoted azide-alkyne cycloaddition (SPAAC) with azide-containing molecules or inverse electron demand Diels-Alder (IEDDA) reactions with tetrazines, enabling post-synthetic oligonucleotide labeling and bioconjugation.
Cat. No.: HY-W540123
CAS No.: 186046-82-2
Target:
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
