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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
405 Results for "
Translation
" in MedChemExpress (MCE) Product Catalog:
Products (405)
405 Results for "Translation" in MCE Product Catalog:
Cat. No.: HY-152203
CAS No.: 318498-81-6
Target:
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Mitochondrial respiration-IN-2 is the fluorine derivative of Virginiamycin M1 (HY-N6686). Mitochondrial respiration-IN-2 can inhibit mitochondrial translation of glioblastoma stem cells .
Cat. No.: HY-116010A
CAS No.: 7060-74-4
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Oleandomycin phosphate is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes .
Research Areas:
Chlorindanol (Clorindanol) is a disinfectant . Chlorindanol inhibits Gram-negative and Gram-positive multiplying bacteria, dermatophytes, fungi, and viral RNA replication/translation. Chlorindanol immobilizes and kills sperm. Chlorindanol is used in the research of flavivirus infection and trichomoniasis .
Cat. No.: HY-176843
CAS No.: 3083974-69-7
Research Areas:
eIF4A-IN-2 (Compound 93) is an Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-2 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-164419
CAS No.: 872063-57-5
Synonyms: COR-004; ATL1103; ISIS 227452
Atesidorsen is a second-generation, antisense oligomer designed to inhibit translation of human growth hormone receptor (GHR) mRNA
Cat. No.: HY-129767
CAS No.: 2368900-35-8
Research Areas:
CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC50 value of 2 nM. CMLD012612 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A) and possesses potent anti-neoplastic activity .
Sparsomycin is a metabolite of the bacterium Streptomyces sparsogenes. Sparsomycin inhibits protein synthesis in both eukaryotic cells and bacteria. Sparsomycin inhibits the translation extension of ribosome PTC .
Cat. No.: HY-177610
CAS No.: 151356-08-0
Synonyms: ISIS 2105
Afovirsen is a 20-mer phosphorothioate oligonucleotide. It is complementary to the mRNA sequence for the translation initiation codon of the E2 protein vital to replication of HPV types 6 and 11.
Cat. No.: HY-177638
CAS No.: 141442-28-6
ISIS 1082 is an antisense oligonucleotide targeted to the translation initiation codon of herpes simplex virus (HSV) type 1 and 2 virion capsid protein. It has been shown to inhibit HSV-1 replication in vitro
Cat. No.: HY-P5723
CAS No.: 1428789-03-0
Cat. No.: HY-144655
CAS No.: 2247640-44-2
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IP2 is an immunomodulatory agent. IP2 increases PTP (Pioneer Translation Product)-derived antigen presentation in cancer cells. IP2 shows non-cytotoxic for cancer cells. IP2 induces tumor growth defects in mouse .
Cat. No.: HY-114489B
Category:
Infection Alkaloids Neurological Disease Amaryllidaceae Extract Plants Sprekelia formosissima (L.) Herb. Disease Research Fields Isoquinoline Alkaloids
Target:
Cat. No.: HY-N13880
CAS No.: 69579-74-4
Category:
Target:
Cat. No.: HY-P11104
CAS No.: 166275-64-5
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Cat. No.: HY-B1864C
CAS No.: 78822-08-9
Synonyms: Ksg sulfate
Target:
Research Areas:
Kasugamycin (Ksg) sulfate is an aminoglycoside antibiotic (antibiotic) that binds to the bacterial 30S ribosomal subunit and inhibits canonical translation initiation. Kasugamycin sulfate binds to the P-site and E-site codon regions in the mRNA channel and interferes with mRNA-tRNA codon-anticodon interactions, thereby destabilizing initiator tRNA binding. Kasugamycin sulfate possesses anti-infective activity. Kasugamycin sulfate is used in research on bacterial translation and Pseudomonas infection .
Cat. No.: HY-121722
CAS No.: 82543-85-9
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Research Areas:
Deoxyhypusine is an unusual amino acid formed during the posttranslational modification of eukaryotic translation initiation factor 5A (eIF-5A) by the enzyme deoxyhypusine hydroxylase (DOHH) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
