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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
405 Results for "
Translation
" in MedChemExpress (MCE) Product Catalog:
Products (405)
405 Results for "Translation" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W019670
CAS No.: 3768-18-1
1
1 Cited Publications
Cat. No.: HY-P2196A
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Infection Alkaloids Neurological Disease Amaryllidaceae Extract Plants Sprekelia formosissima (L.) Herb. Disease Research Fields Isoquinoline Alkaloids
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Silvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively. Anti-cancer activity .
Cat. No.: HY-80003
CAS No.: 1469988-75-7
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QL47, a broad-spectrum antiviral agent, inhibits dengue virus and other RNA viruses. QL47 selectively inhibits eukaryotic translation. QL47 is a potent covalent inhibitor of BTK with an IC50 of 7 nM .
Synonyms: SDS-1-021
CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC50 below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism .
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5-Methoxyuridine is a purine nucleoside analog. 5-Methoxyuridine is present in bacterial tRNA and acts as an innate immune suppressor and protein translation inducer .
Cat. No.: HY-176842
CAS No.: 3083974-55-1
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eIF4A-IN-1 (Compound 79) is an eIF4A inhibitor that inhibits protein translation. eIF4A-IN-1 canb be used in gastric cancer research .
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eIF4A-IN-3, Silvestrol (HY-13251) analogue, is an eIF4A inhibitor. eIF4A-IN-3 blocks protein translation initiation by interfering with eIF4F complex assembly, preferentially inhibiting translation of mRNAs with long, highly structured 5'-untranslated regions. eIF4A-IN-3 inhibits proliferation of human breast cancer cells. eIF4A-IN-3 has moderate apical to basolateral permeability in intestinal cell monolayers and a low efflux ratio .
Cat. No.: HY-153108
Purity: 99.62%
Synonyms: ARCA cap solution (100 mM)
Cat. No.: HY-18292
CAS No.: 102212-26-0
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ARN2966 is a potent, orally active and cross the blood-brain barrier amyloid precursor protein (APP) translation modulator.
Cat. No.: HY-139098
CAS No.: 62828-64-2
Synonyms: m7Gp3G
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7-Methyl-diguanosine triphosphate (m7Gp3G) is an mRNA cap structure analog that inhibits in vitro protein synthesis by binding to the translation initiation complex. 7-Methyl-diguanosine triphosphate binds to eIF4E, promotes cap-dependent translation initiation, stabilizes mRNA, and acts as a translation enhancer. 7-Methyl-diguanosine triphosphate can be used to prepare synthetic capped RNA transcripts for studies related to mRNA translation, splicing, turnover, and intracellular transport .
Cat. No.: HY-164419A
CAS No.: 1826859-79-3
Synonyms: COR-004 sodium; ATL1103 sodium; ISIS 227452 sodium
Atesidorsen sodium is a second-generation, antisense oligomer designed to inhibit translation of human growth hormone receptor (GHR) mRNA
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PXYC1 is a ribosomal protein S1 (RpsA) antagonist with Kds of 0.81 and 0.31 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb) .
Cat. No.: HY-P3270
CAS No.: 11003-38-6
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Cat. No.: HY-P5723A
Cat. No.: HY-E70625
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Casein Kinase 2 (CK2) is a serine/threonine protein kinase that is highly conserved among eukaryotes and has roles in many different cellular processes, such as cell survival, cell cycle regulation, cell polarity, stress responses, transcription and translation .
Cat. No.: HY-14944R
CAS No.: 26833-87-4
Synonyms: Omacetaxine mepesuccinate (Standard); HHT (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
