1234 Results for "

Ac

" in MedChemExpress (MCE) Product Catalog:
Products (1234)

1234 Results for "Ac" in MCE Product Catalog:

Cat. No.: HY-P11066
CAS No.: 1016899-40-3
Target:  

Inhibitory Antibodies

Research Areas:  

Others

RAD-FHR peptide is a self-assembling peptide. RAD-FHR peptide significantly enhances migration, proliferation and growth factor-secretion ability in human adipose stem cells (hASCs). RAD-FHR peptide can be used for synthesis of nanofiber hydrogel for stem cell behaviors research in biomimetic 3D systems .
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Cat. No.: HY-P11287A
DOTA-Pep-1L TFA is a polypeptide formed by the conjugation of DOTA and Pep-1L. DOTA-Pep-1L TFA specifically binds to IL13RA2 and can be used for the synthesis of targeted polypeptides. DOTA-Pep-1L TFA yields the isotopically labeled product [ 225Ac]DOTA-Pep-1L, which exerts α-radiation killing effects on orthotopic glioma cells and extends the median survival time of mice bearing orthotopic glioma models after stereotactic injection. DOTA-Pep-1L TFA can be used for PET imaging, tumor targeting and glioma research .
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Cat. No.: HY-P72328
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H2Ac4; Histone H2A Type 1-B/E; Prev. HIST1H2AB; Histone H2A/M; Prev. H2AFM; HIST1H2AE; H2A/M; Histone H2A/A; Histone Cluster 1 H2A Family Member B; Histone H2A.2; H2A Histone Family, Member M; Histone H2A; Histone Cluster 1, H2ab; H2AFA; H2A Clustered His
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P11065
CAS No.: 958236-89-0
Target:  

Inhibitory Antibodies

Research Areas:  

Others

RAD-SKP peptide is a self-assembling peptide. RAD-SKP peptide with decellularized cartilage matrix (DCM) can be used for synthesis of nanofiber hydrogel. RAD-SKP peptide can be used for cartilage repair research .
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Cat. No.: HY-P11067
Target:  

Inhibitory Antibodies

Research Areas:  

Others

PRG peptide is a self-assembling peptide. PRG peptide significantly enhances endothelial cell survival, proliferation, migration, and morphological tubulogenesis. PRG peptide can be used for tissue regeneration research .
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Cat. No.: HY-P3383A
Synonyms: PL-5 Acetate
Target:  

Bacterial

Research Areas:  

Infection

Peceleganan (PL-5) acetate is an artificial antimicrobial cecropin A (1-10) × melittin B (3-18) hybrid (10+16)-peptide analogue. Peceleganan acetate inhibits wound infection .
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Cat. No.: HY-P11597
CAS No.: 2775373-65-2
Synonyms: CY-101
Target:  

Wnt β-catenin

Research Areas:  

Cancer

Getacatetide (CY-101) is a peptide-based Wnt/β-catenin inhibitor, which can be used for the study of solid tumors .
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Cat. No.: HY-P11841
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

tP4-CPP12 is a RMI1/2 heterodimer inhibitor with an IC50 of 110 nM. tP4-CPP12 binds competitively at the FANCM-RMI interaction site and disrupts endogenous FANCM-RMI protein-protein interactions. tP4-CPP12 induces antiproliferative effects in ALT-positive osteosarcoma cells. tP4-CPP12 is applicable for the research of ALT-positive osteosarcoma .
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Cat. No.: HY-P10953
CAS No.: 2868985-56-0
Synonyms: PSP 29-mer, anti-inflammatory peptide
Target:  

ERK STAT

Research Areas:  

Inflammation/Immunology

Fulipiftide (PSP 29-mer) is a short peptide derived from pigment epithelium-derived factor (PEDF). Fulipiftide induces the phosphorylation of ERK2 and STAT3, enriches tendon stem/progenitor cell markers, maintains cell stemness, promotes colony formation and niche expansion, and drives cell infiltration into injured tendons. Fulipiftide promotes the oriented formation of collagen fibers, regulates collagen deposition, and reduces inflammatory cell infiltration and neovascularization. Fulipiftide can be used in studies related to acute tendon injury .
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Cat. No.: HY-P11373
CAS No.: 176373-77-6
Target:  

Myosin

α-Myosin (614-643) is a segment of polypeptide of the heavy chain of cardiac α-myosin. α-Myosin has a strong ability to induce autoimmune myocarditis .
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Cat. No.: HY-P5320
Target:  

Apoptosis

Research Areas:  

Others

TAT-BH4 (Bcl-xL) localized mainly at the mitochondria, prevents apoptotic cell death. TAT-BH4 (Bcl-xL) is a fusion peptide that combines the N-terminal cysteine conjugated protein transduction domain of HIV TAT protein (amino acids 49 to 57) with the Bcl-xL BH4 peptide. TAT-BH4 can be used for research of diseases caused by accelerated apoptosis .
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Cat. No.: HY-P5320A
Target:  

Apoptosis

Research Areas:  

Others

TAT-BH4 (Bcl-xL) TFA is localized mainly at the mitochondria, prevents apoptotic cell death. TAT-BH4 (Bcl-xL) is a fusion peptide that combines the N-terminal cysteine conjugated protein transduction domain of HIV TAT protein (amino acids 49 to 57) with the Bcl-xL BH4 peptide. TAT-BH4 TFA can be used for research of diseases caused by accelerated apoptosis .
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Cat. No.: HY-P10386
Target:  

Bcl-2 Family

Research Areas:  

Cancer

155H1 (Compound 11) is a stapled peptide, that covalently binds hMcl1 (172-323) with IC50 of 18 nM .
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Cat. No.: HY-P10851
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

HVEM(14-39) is a B- and T-lymphocyte attenuator (BTLA) peptide inhibitor. HVEM (14-39) can be combined with BTLA with a KD of 0.102 μM. HVEM(14-39) enhances the activation and proliferation of T cells by regulating the expression of BTLA and HVEM in T cells, and promotes the transformation of cells into effector memory T cells. HVEM(14-39) inhibits tumor cell proliferation and promotes late apoptosis. HVEM(14-39) has immunomodulatory effects and can be used in the study of cancer .
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Cat. No.: HY-P12260
CAS No.: 3027489-02-4
Research Areas:  

Cancer

AJICAP reagent 1b is a thiophenyl ester-based site-specific conjugation reagent for antibody modification applications. AJICAP reagent 1b is used in HER2-positive gastric cancer-related research .
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Cat. No.: HY-P5423C
Target:  

Inhibitory Antibodies

Research Areas:  

Others

GALA-Cys is a chemically modified GALA peptide (HY-P5423) that retains GALA functions while acquiring strong covalent conjugation capability. GALA-Cys undergoes pH-driven reversible secondary structure transition, rearranges into an amphipathic α-helix, self-oligomerizes, penetrates lipid membranes to form pores, and disrupts lipid bilayers, thereby enabling endosomal escape and cytosolic cargo delivery. GALA-Cys can be conjugated with lipid DPTE for integration into liposomes, self-assembles into a tilted monolayer on gold surfaces, and serves as a pH-responsive coating for particle surface functionalization. GALA-Cys is applicable to studies related to targeted cargo delivery .
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Cat. No.: HY-172320
CAS No.: 2919596-13-5
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

BMS-986238 is an orally active macrocyclic peptide PD-L1 inhibitor. BMS-986238 can be used in the research of tumors such as solid tumors and lymphomas .
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Cat. No.: HY-P10238
Target:  

Apoptosis

Research Areas:  

Cancer

MYBMIM is an inhibitor for assembly of the molecular MYB:CBP/P300 complex. MYBMIM inhibits growth of leukemia cells .
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Cat. No.: HY-P11766
Synonyms: GALA-cholesterol
Research Areas:  

Cancer

GALA-chol is a cholesterol-conjugated pH-responsive fusion peptide that can serve as a delivery adjuvant. GALA-chol enhances the endocytosis of siRNA RET/PTC1-SQ nanoparticles, inhibits cell viability, and undergoes pH-responsive charge conversion in the acidic lysosomal environment, thereby promoting lysosomal escape of small extracellular vesicle (sEV) cargo. GALA-chol anchors to the sEV membrane and maintains the structural integrity and intrinsic homing activity of sEVs. GALA-chol can be used in studies related to adjuvant delivery .
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Cat. No.: HY-P11766A
Synonyms: GALA-cholesterol TFA
Research Areas:  

Cancer

GALA-chol TFA (GALA-cholesterol TFA) is a cholesterol-conjugated pH-responsive fusion peptide that can serve as a delivery adjuvant. GALA-chol TFA enhances the endocytosis of siRNA RET/PTC1-SQ nanoparticles, inhibits cell viability, and undergoes pH-responsive charge conversion in the acidic lysosomal environment, thereby promoting lysosomal escape of small extracellular vesicle (sEV) cargo. GALA-chol TFA anchors to the sEV membrane and maintains the structural integrity and intrinsic homing activity of sEVs. GALA-chol TFA can be used in studies related to adjuvant delivery .
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