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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
145 Results for "
Amyloid Precursor Protein
" in MedChemExpress (MCE) Product Catalog:
Products (145)
145 Results for "Amyloid Precursor Protein" in MCE Product Catalog:
Cat. No.: HY-P86747
Synonyms: beta-Amyloid(1-42); A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid beta A4 Protein Precursor; Amyloid beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; beta APP; Cerebral Vascular Amyloid Peptide; CTFgamma; CVAP; PN II; PN2; PreA4; Protease nexin II; A beta; Amyloid 1-42.Aβ
Cat. No.: HY-P7522
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: APBA3; Mint-3; Amyloid Beta Precursor Protein Binding Family A Member 3; Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 3 (X11-Like 2); X11L2; Phosphotyrosine-Binding/-Interacting Domain (PTB)-Bearing Protein; Mint3; Amyloid Beta (A4) Precu
Species:
Human
Source:
E. coli
Cat. No.: HY-P704896
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuclein; Synuclein, Alpha (Non A4 Component Of Amyloid Precursor); Α-Synuclein; Synuclein Alpha; Non A4 Component Of Amyloid Precursor
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P86747A
Synonyms: beta-Amyloid(1-42); A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid beta A4 Protein Precursor; Amyloid beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; beta APP; Cerebral Vascular Amyloid Peptide; CTFgamma; CVAP; PN II; PN2; PreA4; Protease nexin II; A beta; Amyloid 1-42.Aβ
Cat. No.: HY-118972
CAS No.: 1250849-11-6
Target:
Research Areas:
TPI-1917-49 is an agent that can cross the blood-brain barrier and reduce amyloid β (Aβ). TPI-1917-49 reduces the production of Aβ peptide segments by promoting the non-amyloidogenic pathway of amyloid precursor protein (APP) (increasing the generation of sAPPα mediated by α-secretase). TPI-1917-49 reduces amyloid plaques in mouse models. TPI-1917-49 can be used in Alzheimer's disease research .
Cat. No.: HY-P706310
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuclein; Synuclein, Alpha (Non A4 Component Of Amyloid Precursor); Α-Synuclein; Synuclein Alpha; Non A4 Component Of Amyloid Precursor
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P706269
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ¹⁵N-Alpha-synuclein; ¹⁵N-α-Synuclein; ¹⁵N-NACP; ¹⁵N-Non-A beta component of AD Amyloid; ¹⁵N-Non-A4 component of Amyloid Precursor; ¹⁵N-PARK1; SNCA; Parkinson Disease (Autosomal Dominant; Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuclein; Synuclein; Alpha (Non A4 Component Of Amyloid Precursor); Α-Synuclein; Synuclein Alpha; Non A4 Component Of Amyloid Precursor
Species:
Human
Source:
E. coli
Cat. No.: HY-103374B
CAS No.: 159652-53-6
Synonyms: (±)-Eseroline phenylcarbamate
Target:
Research Areas:
(±)Phenserine ((±)-Eseroline phenylcarbamate) is the racemic form of Phenserine (HY-103374). Phenserine is a derivative of Physostigmine (HY-N6608) and is an effective, non-competitive, long-acting and selective AChE inhibitor. Phenserine can reduce the formation of β-amyloid precursor protein (APP) and β-amyloid peptide (Aβ). Phenserine can improve cognitive ability and slow down the progression of Alzheimer's disease .
Cat. No.: HY-P702529
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NAE1; Proto-Oncogene Protein 1; Prev. APPBP1; NEDD8-Activating Enzyme E1 Subunit; APP-BP1; Alternative Protein NAE1; Ula-1; Protooncogene Protein 1; Amyloid Beta Precursor Protein-Binding Protein 1, 59 KDa; A-116A10.1; Amyloid Beta Precursor Protein Bindi
Species:
Human
Source:
E. coli
Cat. No.: HY-P75588
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BACE2; Memapsin-1; Prev. AEPLC; Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme 2; ALP56; Beta-Site Amyloid Precursor Protein Cleaving Enzyme 2; ASP1; Down Syndrome Region Aspartic Protease; DRAP; Transmembrane Aspartic Proteinase Asp1; Aspart
Species:
Mouse
Source:
HEK293
Cat. No.: HY-187132
CAS No.: 181139-85-5
Target:
Research Areas:
SIB-1281 is a β-secretase inhibitor that inhibits β-site cleavage of amyloid precursor protein (APP) and reduces the production of Aβ peptides. SIB-1281 decreases the generation of Aβ40 and Aβ42, and promotes the secretion of α-sAPP. SIB-1281 can be used in studies related to Alzheimer's disease .
Cat. No.: HY-N13064
CAS No.: 123702-96-5
Category:
Target:
Cat. No.: HY-169197
CAS No.: 2276762-07-1
Target:
Research Areas:
D-688 is an inhibitor of Tau and Aβ. D-688 can reverse Aβ1–42-induced toxicity in SH-SH5Y cells and has significant neuroprotective properties. D-688 can improve the survival rate of Drosophila melanogaster expressing the human tau protein isoform (2N4R) .
Cat. No.: HY-P70660
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P705391
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:
Cynomolgus
Source:
E. coli
Cat. No.: HY-173226
Target:
Research Areas:
BACE1-IN-15 (Compound 72) is a selective inhibitor of beta-site amyloid precursor protein cleaving enzyme 1 (BACE-1) with oral activity and the ability to penetrate the blood-brain barrier. Its IC50 value is 121.65 nM (the IC50 value for BACE-2 is 480.92 nM). BACE1-IN-15 can be used in the research of the Alzheimer's disease field
Cat. No.: HY-14442
CAS No.: 186826-17-5
Target:
Research Areas:
ML 10302 hydrochloride is a potent and selective 5-HT4 receptor agonist, with an EC50 of 4 nM. ML 10302 hydrochloride displays more than 680-fold selectivity over 5-HT3 receptor in binding assay .
Cat. No.: HY-13240A
CAS No.: 1262036-49-6
Target:
Research Areas:
LY2886721 hydrochloride is a potent, selective and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 20.3 nM for recombinant human BACE1. LY2886721 hydrochloride is selectivity against cathepsin D, pepsin, and renin, but lacking selectivity against BACE2 (IC50 of 10.2 nM). LY2886721 hydrochloride can across blood-brain barrier and has the potential for Alzheimer's disease treatment .
Cat. No.: HY-P704889
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:
Human
Source:
HEK293
Cat. No.: HY-P704891
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SNCA; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Prev. PARK1; Non-A4 Component Of Amyloid Precursor; Prev. PARK4; Non A-Beta Component Of AD Amyloid; Alpha-Synuclein; Non-A Beta Component Of AD Amyloid; NACP; Synuclein Alpha-140; PD1; I+/--Synuc
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
