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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1427 Results for "
M2 Macrophage Reprogramming
" in MedChemExpress (MCE) Product Catalog:
Products (1427)
1427 Results for "M2 Macrophage Reprogramming" in MCE Product Catalog:
Cat. No.: HY-P7265
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL18; Macrophage Inflammatory Protein 4; Prev. SCYA18; C-C Motif Chemokine 18; DC-CK1; CC Chemokine PARC; AMAC-1; AMAC1; DCCK1; Pulmonary And Activation-Regulated; MIP-4; Chemokine (C-C Motif) Ligand 18; PARC; Small Inducible Cytokine A18; CKb7; Small-In
Species:
Human
Source:
E. coli
Cat. No.: HY-P72759
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL18; Macrophage Inflammatory Protein 4; Prev. SCYA18; C-C Motif Chemokine 18; DC-CK1; CC Chemokine PARC; AMAC-1; AMAC1; DCCK1; Pulmonary And Activation-Regulated; MIP-4; Chemokine (C-C Motif) Ligand 18; PARC; Small Inducible Cytokine A18; CKb7; Small-In
Species:
Human
Source:
E. coli
Cat. No.: HY-P72396
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LILRB2; Monocyte/Macrophage Immunoglobulin-Like Receptor 10; Leukocyte Immunoglobulin Like Receptor B2; CD85 Antigen-Like Family Member D; MIR-10; Myeloid Inhibitory Receptor 10; LIR-2; Leucocyte Ig-Like Receptor B2; MIR10; ILT-4; ILT4; Leukocyte Immunogl
Species:
Human
Source:
HEK293
Cat. No.: HY-P72678
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL3; C-X-C Motif Chemokine 3; Prev. GRO3; GRO3 Oncogene; SCYB3; GRO-Gamma; CINC-2b; MIP2-Beta; MIP-2b; Melanoma Growth Stimulatory Activity Gamma; GROg; MGSA Gamma; Macrophage Inflammatory Protein 2-Beta; MIP2B; Chemokine (C-X-C Motif) Ligand 3; GROG; G
Species:
Human
Source:
E. coli
Cat. No.: HY-P74342
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCL4; Act-2; Prev. SCYA4; MIP1B; Prev. LAG1; HC21; MIP-1-Beta; Monocyte Adherence-Induced Protein 5 Alpha; AT744.1; Chemokine C-C Motif Ligand 4; Small Inducible Cytokine A4 (Homologous To Mouse Mip-1b); Small-Inducible Cytokine A4; Macrophage Inflammator
Species:
Human
Source:
P. pastoris
Cat. No.: HY-P78483
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LILRB2; Monocyte/Macrophage Immunoglobulin-Like Receptor 10; Leukocyte Immunoglobulin Like Receptor B2; CD85 Antigen-Like Family Member D; MIR-10; Myeloid Inhibitory Receptor 10; LIR-2; Leucocyte Ig-Like Receptor B2; MIR10; ILT-4; ILT4; Leukocyte Immunogl
Species:
Human
Source:
HEK293
Cat. No.: HY-P700165AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL4; Act-2; Prev. SCYA4; MIP1B; Prev. LAG1; HC21; MIP-1-Beta; Monocyte Adherence-Induced Protein 5 Alpha; AT744.1; Chemokine C-C Motif Ligand 4; Small Inducible Cytokine A4 (Homologous To Mouse Mip-1b); Small-Inducible Cytokine A4; Macrophage Inflammator
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P700175AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPBP; Macrophage-Derived Growth Factor; Prev. THBGB1; C-X-C Motif Chemokine 7; SCYB7; Beta-Thromboglobulin; CTAP3; NAP-2-L1; CXCL7; Small Inducible Cytokine Subfamily B, Member 7; MDGF; Neutrophil-Activating Peptide-2; LDGF; Low-Affinity Platelet Factor I
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P700003
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL3; C-X-C Motif Chemokine 3; Prev. GRO3; GRO3 Oncogene; SCYB3; GRO-Gamma; CINC-2b; MIP2-Beta; MIP-2b; Melanoma Growth Stimulatory Activity Gamma; GROg; MGSA Gamma; Macrophage Inflammatory Protein 2-Beta; MIP2B; Chemokine (C-X-C Motif) Ligand 3; GROG; G
Species:
Mouse
Source:
CHO
Cat. No.: HY-P700545
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCL18; Macrophage Inflammatory Protein 4; Prev. SCYA18; C-C Motif Chemokine 18; DC-CK1; CC Chemokine PARC; AMAC-1; AMAC1; DCCK1; Pulmonary And Activation-Regulated; MIP-4; Chemokine (C-C Motif) Ligand 18; PARC; Small Inducible Cytokine A18; CKb7; Small-In
Species:
Human
Source:
P. pastoris
Cat. No.: HY-P700759
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAM; Human Neutrophil Antigen 4; Prev. CR3A; HNA-4; Prev. CD11B; Integrin, Alpha M (Complement Component Receptor 3, Alpha; Also Known As CD11b (P170), Macrophage Antigen Alpha Polypeptide); Integrin Alpha-M; Neutrophil Adherence Receptor Alpha-M Subuni
Species:
Human
Source:
HEK293
Cat. No.: HY-P704188
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ZBP1; Z-DNA Binding Protein 1; alias:C20orf183; DLM1; DAI; Tumor Stroma And Activated Macrophage Protein DLM-1; Z-DNA-Binding Protein 1; DLM-1; DNA-Dependent Activator Of IRFs; DJ718J7.3; DNA-Dependent Activator Of IFN-Regulatory Factors; Chromosome 20 Op
Species:
Human
Source:
E. coli
Cat. No.: HY-P704783
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL22; Macrophage-Derived Chemokine; Prev. SCYA22; CC Chemokine STCP-1; MDC; MDC(1-69); A-152E5.1; MGC34554; DC/B-CK; Stimulated T Cell Chemotactic Protein 1; STCP-1; Stimulated T-Cell Chemotactic Protein 1; ABCD-1; Small Inducible Cytokine A22; Small Ind
Species:
Human
Source:
HEK293
Cat. No.: HY-P7248B
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCL22; Macrophage-Derived Chemokine; Prev. SCYA22; CC Chemokine STCP-1; MDC; MDC(1-69); A-152E5.1; MGC34554; DC/B-CK; Stimulated T Cell Chemotactic Protein 1; STCP-1; Stimulated T-Cell Chemotactic Protein 1; ABCD-1; Small Inducible Cytokine A22; Small Ind
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P705979
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CCR1; MIP-1alpha-R; Prev. CMKBR1; CC-CKR-1; Prev. SCYAR1; RANTES-R; Chemokine (C-C Motif) Receptor 1; HM145; MIP1aR; CCR-1; CKR-1; RANTES Receptor; CD191; CD191 Antigen; Macrophage Inflammatory Protein 1-Alpha Receptor; CMKR1; C-C Chemokine Receptor Type
Species:
Human
Source:
HEK293
Cat. No.: HY-10952
CAS No.: 357605-73-3
Research Areas:
ONO-AE2-227 is an orally active EP4 receptor antagonist. ONO-AE2-227 blocks PGE2-mediated EP4 signaling by competitively antagonizing PGE2-induced cAMP elevation, and binds to EP4/EP3 with mouse Ki values of 2.7/21 nM. ONO-AE2-227 reduces aberrant crypt foci and intestinal polyp development, and inhibits intestinal polyp formation. ONO-AE2-227 enhances LPS-induced TNF-alpha release from human alveolar macrophages by blocking endogenous PGE2, blocks PGE2-induced ICAM-1 expression and leukocyte-endothelial adhesion, and attenuates PGE2-induced monocyte adhesion to brain endothelial cells. ONO-AE2-227 can be used for research on colon cancer .
Cat. No.: HY-177414
Research Areas:
BB-1701 is an anti-HER2 antibody-drug conjugate (ADC). BB-1701 consists of a humanized anti-HER2 antibody (Trastuzumab) (HY-P9907), a linker (Mal-PEG2-VCP), and a microtubule inhibitor (Eribulin) (HY-13442), with the drug-linker conjugate of the ADC being Mal-PEG2-VCP-Eribulin (HY-128870). BB-1701 exhibits potent cytotoxicity against various cancer cells, shows a remarkable bystander effect, and induces immunogenic cell death (upregulated cell surface expression of calreticulin, release of ATP/HMGB1, macrophage infiltration) and apoptosis. BB-1701 potently inhibits tumor growth in T-DM1/T-DXd-resistant tumor models. BB-1701 can be used in studies related to breast cancer, gastric cancer, non-small cell lung cancer, and heterogeneous mixed tumors .
Cat. No.: HY-187035
CAS No.: 868066-26-6
SNX631 is an orally active and selective CDK8/CDK19 inhibitor. SNX631 reduces the phosphorylation of STAT1/STAT3 S727, and upregulates miR-21-5p, miR-21-3p and miR-221 in cancer cells. SNX631 transcription-independently inhibits meiotic resumption in mouse oocytes, blocks nuclear envelope breakdown, first polar body extrusion and mitochondrial expansion and aggregation, with no cytotoxicity. SNX631, in combination with Lapatinib (HY-50898) or Trastuzumab (HY-P9907), synergistically inhibits cancer cell growth, upregulates the tumor suppressor BTG2, prevents Lapatinib-induced upregulation of oncogenic miRNAs, overcomes drug resistance, reduces the infiltration of αSMA+ stromal fibroblasts and ARG1+ M2 macrophages, and exhibits favorable biosafety. SNX631 can be used in studies related to HER2-positive breast cancer and cancer .
Cat. No.: HY-N2942
CAS No.: 52328-96-8
Cat. No.: HY-N9454
CAS No.: 91893-83-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
