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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
368 Results for "
limb perfusion method
" in MedChemExpress (MCE) Product Catalog:
Products (368)
368 Results for "limb perfusion method" in MCE Product Catalog:
Cat. No.: HY-158024B
CAS No.: 2272918-42-8
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(rac)-NDT-19795 is the racemate of NDT-19795 (HY-158024). NDT-19795 is an effective inhibitor of the NLRP3 inflammasome with an IC50 value of 66 nM in the PBMC method and 4.7 μM in the WB method. NDT-19795 is a carboxylic acid-active substance that can be converted from NT-0796 (HY-156438) within cells. NDT-19795 can be used for the studies of inflammation and neurological diseases .
Cat. No.: HY-182414
CAS No.: 81907-78-0
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NCO-650 free base is an antiallergic agent that acts by inhibiting tryptase, a key trypsin-like protease in mast cells. NCO-650 free base inhibits mast cell histamine release, increases intracellular cAMP levels in mast cells, suppresses bronchoconstriction, and prevents decreases in perfusion pressure and systemic blood pressure. NCO-650 free base is applicable to the research of allergic diseases and bronchial asthma .
Cat. No.: HY-W794347
CAS No.: 156547-62-5
Synonyms: Salbutamol impurity J
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Salbutamol impurity 2 (Salbutamol impurity J) is an impurity of Salbutamol. Salbutamol impurity 2 can be used for impurity identification, analytical method development, and quality-control research related to Salbutamol.
Cat. No.: HY-148605
CAS No.: 119610-26-3
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Cardiovascular Disease Neurological Disease Inflammation/Immunology
Aloracetam is a γ-aminobutyric acid cyclic derivative that can pass through the blood-brain barrier and has a significant enhancing cognitive function effect. Aloracetam improves the blood perfusion of brain tissue, increases the synthesis of proteins, ATP and acetylcholine in the brain, enhances the excitatory conduction effect of cholinergic nerves, and reduces the damage to brain tissue caused by cerebral vascular diseases. Aloracetam also has certain anti-epileptic, anti-inflammatory, analgesic and anti-depressant effects .
Cat. No.: HY-161909
CAS No.: 2511541-78-7
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USP30-IN-1 is a potent and selective USP30 inhibitor, with IC50 values of 94 nM and 4 nM in vivo and in vitro, respectively, and Ki values of 0.33 μM (Krippendorf method) and 0.38 μM (traditional method), respectively. USP30-IN-1 covalently binds to the catalytic cysteine (Cys77) of USP30, blocks ubiquitin substrate binding to inhibit deubiquitination, and ultimately induces mitophagy. USP30-IN-1 can be used for the research of idiopathic Parkinson's disease and mitophagy-related diseases .
Cat. No.: HY-W203147
CAS No.: 26330-06-3
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1-Azidopentane is comprised of an azide group attached to a 5-carbon tail. 1-Azidopentane is used in preparation method of multi-axis liquid crystal refrigeration material by click chemistry.
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Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis. Oxyfluorfen can inhibit cell growth. Oxyfluorfen induces DNA damage and exhibits toxicity toward aquatic organisms such as Paramisgurnus dabryanus. Oxyfluorfen has genome-level deleterious effects on fish that can lead to stunted skeletal growth. Oxyfluorfen induces transverse limb deficiency or craniosynostosis .
Cat. No.: HY-176886
CAS No.: 2248728-49-4
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LATS-IN-2 is an efficiently acting LATS (large tumor suppressor kinase) inhibitor. LATS-IN-2 shows potent inhibitory activity against LATS1 with an IC50 value of 1.3 nM. LATS-IN-2 suppresses the phosphorylation of YAP by inhibiting LATS kinase activity. LATS-IN-2 increases the thickness of the epidermis in mice. LATS-IN-2 can be used for the study of ocular diseases such as limbal stem cell deficiency and corneal endothelial dysfunction .
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Naftidrofuryl oxalate (Nafronyl oxalate salt) is an orally active 5-HT2 receptor antagonist. Naftidrofuryl oxalate selectively blocks vascular and platelet 5-HT2 receptors, inhibiting Serotonin (HY-B1473A)-induced vasoconstriction, platelet aggregation, and vascular smooth muscle cell proliferation. Naftidrofuryl oxalate can be used for the research of intermittent claudication, peripheral occlusive arterial disease, and critical limb ischaemia .
Cat. No.: HY-P9S0008
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Cat. No.: HY-W568314
CAS No.: 2135333-04-7
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Vericiguat impurity-1 is the impurity of Vericiguat (HY-16774). Vericiguat impurity-1 can be used as impurity standards in impurity analysis, to develop selective and quantitative methods to determine impurities .
Cat. No.: HY-B0528AR
CAS No.: 770-05-8
Synonyms: (±)-p-Octopamine hydrochloride (Standard)
Category:
Cat. No.: HY-164227
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Vericiguat impurity-2 is the impurity of Vericiguat (HY-16774). Vericiguat impurity-2 can be used as impurity standards in impurity analysis, in order to develop selective and quantitative methods to determine impurities .
Cat. No.: HY-W173921
CAS No.: 6926-45-0
Synonyms: Hexyl azide
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1-Azidohexane (Hexyl azide) is comprised of an azide group attached to a 6-carbon tail. 1-Azidohexane is used in preparation method of multi-axis liquid crystal refrigeration material by click chemistry.
Cat. No.: HY-132601C
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Cobomarsen scrambled control is the negative control form of Cobomarsen (HY-132601), with the sequence: ACAUCAUAGUGACU. The modification method is the same as that of Cobomarsen. Cobomarsen sodium is an oligonucleotide inhibitor of miR-155 and can be used in the research of B-cell lymphoma.
Cat. No.: HY-168377
CAS No.: 1199351-32-0
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Fluo-4 potassium is a cell-impermeable Ca 2+ (calcium ion) indicator (λex=494 nm, λem=516 nm). Fluo-4 potassium can be introduced into cells using methods such as patch clamping and microinjection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
