3200-06-4
Chemical Structure
Naftidrofuryl oxalate
Synonym(s): Nafronyl oxalate salt
- CAS No.: 3200-06-4
- Formula:C26H35NO7
- Molecular Weight:473.56
IUPAC Name: 2-(diethylamino)ethyl 3-(naphthalen-1-yl)-2-((tetrahydrofuran-2-yl)methyl)propanoate oxalate
InChIKey: SSAJNPNVUYMUCI-UHFFFAOYSA-N
SMILES: O=C(OCCN(CC)CC)C(CC1=C2C=CC=CC2=CC=C1)CC3OCCC3.O=C(O)C(O)=O
Biological Activity: Naftidrofuryl oxalate (Nafronyl oxalate salt) is an orally active 5-HT2 receptor antagonist. Naftidrofuryl oxalate selectively blocks vascular and platelet 5-HT2 receptors, inhibiting Serotonin (HY-B1473A)-induced vasoconstriction, platelet aggregation, and vascular smooth muscle cell proliferation. Naftidrofuryl oxalate can be used for the research of intermittent claudication, peripheral occlusive arterial disease, and critical limb ischaemia[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Naftidrofuryl oxalate | 99.94% | Naftidrofuryl oxalate (Nafronyl oxalate salt) is an orally active 5-HT2 receptor antagonist. Naftidrofuryl oxalate selectively blocks vascular and platelet 5-HT2 receptors, inhibiting Serotonin (HY-B1473A)-induced vasoconstriction, platelet aggregation, and vascular smooth muscle cell proliferation. Naftidrofuryl oxalate can be used for the research of intermittent claudication, peripheral occlusive arterial disease, and critical limb ischaemia. | ||||||||||||||||||||
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Naftidrofuryl oxalate (Standard) | ≥98% | Naftidrofuryl (oxalate) (Standard) is the analytical standard of Naftidrofuryl (oxalate). This product is intended for research and analytical applications. | ||||||||||||||||||||
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- [1]. de Backer TL, et al. Naftidrofuryl for intermittent claudication. Cochrane Database Syst Rev. 2012 Dec 12;12(12):CD001368. [Content Brief]
- [2]. Barradell LB, et al. A review of its pharmacology and therapeutic use in the management of peripheral occlusive arterial disease. Drugs Aging. 1996 Apr;8(4):299-322. [Content Brief]
- [3]. Smith FB, et al. Intravenous naftidrofuryl for critical limb ischaemia. Cochrane Database Syst Rev. 2012 Jul 11;2012(7):CD002070. [Content Brief]
