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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
α-glucosidase Enzyme Inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "α-glucosidase Enzyme Inhibitor" in MCE Product Catalog:
4
Category:
Flavonoids Leguminosae Flavonones Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Cancer
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3
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Miglitol (BAY-m1099) is an orally active antidiabetic compound that inhibits the breakdown of glycoconjugates into glucose. Miglitol inhibits glycoside hydrolase enzymes called α-glucosidases. Miglitol inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase. Dietary supplementation with Miglitol from pre-onset stage in OLETF rats delays the onset and development of diabetes and preserves the insulin secretory function of pancreatic islets .
2
Category:
Tribulus terrester Linn. Zygophyllaceae Metabolic Disease Plants Disease Research Fields Steroids
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2 Cited Publications
Synonyms: Quercetin-7-O-β-D-glucopyranoside
Category:
Flavonols Ginkgoaceae Metabolic Disease Plants Compositae Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Derris scandens Ginkgo biloba L. Disease Research Fields
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Cat. No.: HY-N0466
CAS No.: 58543-16-1
Category:
Cardiovascular Disease Alkaloids other families Phenols Polyphenols Plants Disease Research Fields Isoquinoline Alkaloids
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Cat. No.: HY-N3542
CAS No.: 57498-96-1
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Flavonoids Flavones Plants Calophyllaceae Calophyllum symingtonianum M.R.Hend. & Wyatt-Sm.
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Cat. No.: HY-N9454
CAS No.: 91893-83-3
Cat. No.: HY-155372
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α-Glucosidase-IN-39 is a potent inhibitor of α-glucosidase enzyme with an IC50 of 869.06 ppm. α-Glucosidase-IN-39 can used in study antidiabetic .
Cat. No.: HY-N0466R
CAS No.: 58543-16-1
Cat. No.: HY-156447
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α-Glucosidase-IN-40 (compound 5) is a noncompetitive α-glucosidase enzyme inhibitor with an IC50 of 24.62 μM .
Cat. No.: HY-149668
CAS No.: 3012673-89-8
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α-Glucosidase-IN-41 (compound 5o) is a potent α-glucosidase inhibitor. α-Glucosidase-IN-41 can arise the changed secondary structure of α-Glu to hinder enzyme catalytic activity. α-Glucosidase-IN-41 can be used for diabetes mellitus research .
Cat. No.: HY-161355
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α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor for both α-amylase (IC50 = 16.4 μM) and α-glucosidase (IC50 = 31.6 μM) enzymes .
Cat. No.: HY-172757
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α-Glucosidase-IN-88 (Compound 3K) is an orally active and potent α-glucosidase inhibitor with an IC50 value of 6.40 µM. α-Glucosidase-IN-88 inhibits carbohydrate hydrolysis by blocking the enzyme's ability to break down glycosidic bonds, thereby reducing postprandial blood glucose levels. α-Glucosidase-IN-88 is promising for research of type 2 diabetes mellitus (T2DM) .
Cat. No.: HY-162390
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α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is a isoxazolidine-isatin hybrid with significant antidiabetic activity. α-Amylase/α-Glucosidase-IN-11 competitively inhibits α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM), two key digestive enzymes. α-Amylase/α-Glucosidase-IN-11 does not cross the blood-brain barrier .
Cat. No.: HY-162036
CAS No.: 1038094-94-8
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α-Amylase/α-Glucosidase-IN-7 (Compound 3f) is a competitive α-glucosidase and α-amylase enzyme inhibitor with IC50 values of 18.52 and 20.25 µM, respectively. α-Amylase/α-Glucosidase-IN-7 can also effectively inhibit AChE and BChE, with IC50 values of 9.25 and 10.06 µM respectively. α-Amylase/α-Glucosidase-IN-7 can be used in diabetes and Alzheimer’s research .
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Category:
Cardiovascular Disease Alkaloids Phenols Polyphenols Nelumbo nucifera Gaertn. Plants Disease Research Fields Isoquinoline Alkaloids Nymphaeaceae
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Nicothiazone is an α-glucosidase inhibitor with a yeast α-glucosidase IC50 of 120.20 μM. Nicothiazone inhibits α-glucosidase enzyme activity. Nicothiazone can be used for the research of type-II diabetes mellitus .
Cat. No.: HY-174223
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Research Areas:
α-Glucosidase-IN-90 (Compound 7b) is an α-Glucosidase inhibitor (IC50: 14.48 nM). α-Glucosidase-IN-90 binds to HIS:280 and ASN:415 residues of α-glucosidase via hydrogen bonds, inhibiting the activity of the enzyme. α-Glucosidase-IN-90 can be used in the study of diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
