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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
ACVR2B
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "ACVR2B" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P99355
CAS No.: 1356922-05-8
Synonyms: Anti-ACVR2B Reference Antibody; BYM338
Target:
Research Areas:
Bimagrumab (Anti-ACVR2B Reference Antibody; BYM338) is a monoclonal antibody targeting activin type II receptors (ActRII). Bimagrumab binds to human ActRIIB (Kd 1.7 pM) and ActRIIA (Kd 434 pM), blocks ligand binding and downstream Smad activation, and inhibits myostatin/activin A-induced Smad phosphorylation. Bimagrumab induces skeletal muscle hypertrophy in an Akt-independent manner via mTOR-mediated muscle protein synthesis, increases muscle mass and strength, promotes myoblast differentiation/fusion, prevents myotube atrophy and glucocorticoid-induced muscle loss, reduces fat mass and fat depot weight/adipocyte size, inhibits adipose inflammation, induces fat oxidation, preserves lean body mass during incretin-induced weight loss, and enhances the appetite-suppressive effect of incretins. Bimagrumab can be used in research on obesity and skeletal muscle atrophy and weakness [2] .
Cat. No.: HY-RS00249
Target:
Research Areas:
Acvr2b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acvr2b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990327
Synonyms: humZ270 mAb
Target:
Research Areas:
Cat. No.: HY-RS00248
Target:
Research Areas:
ACVR2B Human Pre-designed siRNA Set A contains three designed siRNAs for ACVR2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00250
Target:
Research Areas:
Acvr2b Rat Pre-designed siRNA Set A contains three designed siRNAs for Acvr2b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174782
Target:
Research Areas:
Human ACVR2B mRNA encodes the human activin A receptor type 2B (ACVR2B) protein, a receptor that transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis.
Cat. No.: HY-P77290
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P75536
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P703956
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
HEK293
Cat. No.: HY-P7456
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
HEK293
Cat. No.: HY-P72813
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
HEK293
Cat. No.: HY-P75535
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P704973
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Cynomolgus
Human
Source:
HEK293
Cat. No.: HY-P704974
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
HEK293
Cat. No.: HY-P703681
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Rat
Source:
HEK293
Cat. No.: HY-P87263A
Synonyms: Activin receptor type-2B; Activin receptor type IIB; ACTR-IIB; ACVR2B
Cat. No.: HY-P703526
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR2B; Serine/Threonine-Protein Kinase Receptor; Activin A Receptor Type 2B; Activin Receptor Type IIB; ActR-IIB; ACTR-IIB; Activin A Receptor, Type IIB; ACTRIIB; Activin Receptor Type-2B; HTX4
Species:
Human
Cynomolgus
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
