25 Results for "

APRIL

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "APRIL" in MCE Product Catalog:

Cat. No.: HY-P99568
CAS No.: 2136630-26-5
Synonyms: RC18

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Telitacicept (RC18) is a fully human TACI-Fc fusion protein. Telitacicept is a dual B lymphocyte stimulator (BLyS)/APRIL (a proliferation-inducing ligand) inhibitor that effectively blocks proliferation of B lymphocytes. Telitacicept can be used in research of B-cell autoimmune disease . The component ratio of this product is Active ingredient : Excipients = 1: 0.5-1: 0.8.
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Cat. No.: HY-P99901
CAS No.: 2382896-07-1
Synonyms: VIS649

Target:  

SARS-CoV

Research Areas:  

Inflammation/Immunology Cancer

Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand (APRIL). Sibeprenlimab suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) .
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Cat. No.: HY-P990706
CAS No.: 2490217-42-8
Synonyms: ALPN-303

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Povetacicept (ALPN-303) is an engineered Fc fusion protein containing the TACI domain, and acts as a dual APRIL/BAFF antagonist. The Kd value of Povetacicept for human BAFF is 59.3 pM, while its Kd value for human APRIL is 1.00 pM. Povetacicept reduces the activation, proliferation, differentiation and survival of B cells, and inhibits the production of immunoglobulins and autoantibodies. Povetacicept can be used in research related to autoimmune hemolytic anemia, immune thrombocytopenia, systemic lupus erythematosus, lupus nephritis and myasthenia gravis .
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Cat. No.: HY-P990070
CAS No.: 2642175-46-8
Synonyms: BION-1301

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Zigakibart (BION-1301) is an IgG4-kappa, humanized monoclonal antibody against TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256). Zigakibart exhibits anti-inflammatory activity .
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Cat. No.: HY-P991490

Target:  

CD38 CD3 TNF Receptor

Research Areas:  

Cancer

ISB2001 is a trispecific antibody targeting CD38, CD3 and BCMA. ISB2001 effectively counteracts tumor immune escape mechanisms caused by antigen downregulation, antigen loss, soluble factor competition and other factors. ISB2001 is applicable to relevant research on multiple myeloma and relapsed/refractory multiple myeloma .
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Cat. No.: HY-P991538

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

VIS954 is an anti-APRIL monoclonal antibody. VIS954 can be studied in research for anti-neutrophil cytoplasmic antibody-associated vasculitis (ANCA Vasculitis) and IgA nephrophathy .
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Cat. No.: HY-RS00752
Research Areas:  

Others

ANP32B Human Pre-designed siRNA Set A contains three designed siRNAs for ANP32B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17239
Research Areas:  

Others

Tnfsf13 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfsf13 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14823
Research Areas:  

Others

TNFSF13 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFSF13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P82513
Synonyms: APRIL; CD256; TALL2; TNFSF13; TRDL1; ZTNF2

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7538
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuAPRIL/TNFSF13, N-Fc; CD256; TALL2; APRIL; TNFSF13
Species:  
Source:  
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Cat. No.: HY-P77564
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik
Species:  
Source:  
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Cat. No.: HY-P704980
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik
Species:  
Source:  
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Cat. No.: HY-P700661
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik
Species:  
Source:  
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Cat. No.: HY-P704981
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik
Species:  
Source:  
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Cat. No.: HY-P70733
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256; TNFSF13
Species:  
Source:  
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Cat. No.: HY-P70733A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256; TNFSF13
Species:  
Source:  
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Cat. No.: HY-P992101
CAS No.: 3057276-00-0
Synonyms: AUR-200
Aritinercept (AUR-200) is a recombinant fusion protein targeting TNFSF13B/BAFF/CD257. Aritinercept neutralizes BAFF and APRIL (TNFSF13), reduces B cell proliferation, suppresses peripheral B cells, lowers serum immunoglobulins. Aritinercept reduces renal damage markers, decreases IFNγ, IL-17A, and anti-dsDNA autoantibodies, and improves survival in a mouse model of SLE. ritinercept can be used for the research of systemic lupus erythematosus .
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Cat. No.: HY-P700016AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF13; CD256; TALL-2; TALL2; TNLG7B; TRDL-1; UNQ383/PRO715; ZTNF2
Species:  
Source:  
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Cat. No.: HY-RS23693
Research Areas:  

Others

Tnfsf13 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tnfsf13 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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