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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
ASK2
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "ASK2" in MCE Product Catalog:
TC ASK 10 (Compound 10) is a potent, selective and orally active apoptosis signal-regulating kinase 1 (ASK1) inhibitor with an IC50 of 14 nM. The inhibitory activities of TC ASK 10 towards other representative panel of kinases are less than 50%, except for ASK2 (IC50 of 0.51 μM) .
Cat. No.: HY-152247
CAS No.: 2673364-10-6
DDO3711, a PP5-recruiting phosphatase recruitment chimeras (PHORCs), is formed by connecting a small molecular apoptosis signal-regulated kinase 1 (ASK1) inhibitor to a PP5 activator through a chemical linker. DDO3711 specifically inhibits ASK1 (IC50 =164.1 nM) not ASK2 (IC50>20 μM). DDO3711 significantly dephosphorylates p-ASK1 T838 by recruiting PP5 and shows the ASK1-dependent antiproliferative activity. DDO3711 has anti-cancer activity and has the potential for abnormally phosphorylated oncoproteins research .
Cat. No.: HY-P703257
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K6; Apoptosis Signal-Regulating Kinase 2; Mitogen-Activated Protein Kinase Kinase Kinase 6; Mitogen-Activated Protein Kinase Kinase Kinase; MAPKKK6; Apoptosis Signal Regulating Kinase 2; MEKK6; Alternative Protein MAP3K6; ASK2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-103258R
CAS No.: 1005775-56-3
Target:
Research Areas:
TC ASK 10 (Standard) is the analytical standard of TC ASK 10 (HY-103258). This product is intended for research and analytical applications. TC ASK 10 (Compound 10) is a potent, selective and orally active apoptosis signal-regulating kinase 1 (ASK1) inhibitor with an IC50 of 14 nM. The inhibitory activities of TC ASK 10 towards other representative panel of kinases are less than 50%, except for ASK2 (IC50 of 0.51 μM) .
Cat. No.: HY-RS08061
Target:
Research Areas:
MAP3K6 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP3K6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21151
Target:
Research Areas:
Map3k6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map3k6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
