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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
ATF1
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "ATF1" in MCE Product Catalog:
5
2
2 Cited Publications
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BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells [1].
1
1 Cited Publications
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
SB-699551 is a selective and brain penetrant 5-HT5A receptor antagonist with a pKi of 8.2 nM. SB-699551 shows high selectivity over most other 5-HT receptor subtypes, dopamine receptors, and α1B adrenoceptor. SB-699551 disrupts Gαi/o-coupled and PI3K/AKT/mTOR signaling pathways, alters CREB, ATF1, AKT, PRAS40, S6K, and FOXO1 phosphorylation in breast tumor cells. SB-699551 can be used for the research of anxiety, breast cancer, and Alzheimer's disease [1] .
1
Cat. No.: HY-RS01127
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ATF1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18337
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Atf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24816
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Atf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Atf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P83391A
Synonyms: Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1 Protein TREB36; ATF1
Cat. No.: HY-P810358
Synonyms: Activating transcription factor 1, ATF 1, ATF1, ATF1 EWS fusion gene, ATF1 FUS fusion gene, ATF1_HUMAN, cAMP dependent transcription factor 1, cAMP-dependent transcription factor ATF-1, Cyclic AMP dependent transcription factor ATF 1, Cyclic AMP dependent transcription factor ATF1
Cat. No.: HY-108618R
CAS No.: 686770-80-9
Research Areas:
BC11-38 (Standard) is the analytical standard of BC11-38 (HY-108618). This product is intended for research and analytical applications. BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells [1].
Cat. No.: HY-RS05361
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Research Areas:
GDNF Human Pre-designed siRNA Set A contains three designed siRNAs for GDNF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N12887
CAS No.: 114582-75-1
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Cat. No.: HY-103100R
CAS No.: 864741-95-7
Target:
Reference Standards 5-HT Receptor Epigenetic Reader Domain Akt Ribosomal S6 Kinase (RSK) FOXO
Research Areas:
SB-699551 (Standard) is the analytical standard of SB-699551 (HY-103100). This product is intended for research and analytical applications. SB-699551 is a potent and selective 5-HT5A antagonist with a Ki value of 5.1 μM. SB-699551 increases the phosphorylation levels of CREB and ATF1, and decreases the phosphorylation levels of AKT, PRAS40, P70S6K, FOXO1, and S6RP. SB-699551 improves drug-induced cognitive deficits. SB-699551 improves social withdrawal and forgetfulness. SB-699551 inhibits breast cancer.
Cat. No.: HY-136700
CAS No.: 791789-61-2
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SB-699551 free base is a selective and brain penetrant 5-HT5A receptor antagonist with a pKi of 8.2 nM. SB-699551 free base shows high selectivity over most other 5-HT receptor subtypes, dopamine receptors, and α1B adrenoceptor. SB-699551 free base disrupts Gαi/o-coupled and PI3K/AKT/mTOR signaling pathways, alters CREB, ATF1, AKT, PRAS40, S6K, and FOXO1 phosphorylation in breast tumor cells. SB-699551 free base can be used for the research of anxiety, breast cancer, and Alzheimer's disease [1] .
Cat. No.: HY-P700084AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3
Cat. No.: HY-P73075
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Glial cell line-derived neurotrophic factor; ATF; HFB1-GDNF; HGDNF; HSCR3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
