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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Andrographolide
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Andrographolide" in MCE Product Catalog:
36
Category:
Infection Acanthaceae Extract Plant Terpenoids Diterpenoids Disease Research Fields Inflammation/Immunology Andrographis paniculata (Burm. F.) Nees Extract
Target:
4
4 Cited Publications
Cat. No.: HY-N1490
CAS No.: 42895-58-9
Synonyms: 14-dehydro Andrographolide; AP10
Category:
Acanthaceae Extract Plant Terpenoids Diterpenoids Disease Research Fields Andrographis paniculata (Burm. F.) Nees Extract Cancer
Target:
Cat. No.: HY-W024485
CAS No.: 368866-07-3
Target:
Research Areas:
SARS-CoV-2-IN-86 is an inhibitor of SARS-CoV-2 methyltransferases nsp14 and nsp16, and a derivative of Andrographolide (HY-N0191). SARS-CoV-2-IN-86 can be used for research on COVID-19 .
Cat. No.: HY-151446
CAS No.: 947699-46-9
Research Areas:
ZIKV-IN-3 (compound 5a), an andrographolide derivatives, is a potent ZIKV NS5 methyl transferase (MTase) inhibitor with an IC50 value of 18.34 μM. ZIKV-IN-3 inhibits ZIKV replication and infection. ZIKV-IN-3 can be used in research of Zika virus (ZIKV) .
Cat. No.: HY-N0191A
CAS No.: 142037-79-4
Synonyms: 14-EpiAndrographolide
Category:
Acanthaceae Extract Plant Terpenoids Diterpenoids Andrographis paniculata (Burm. F.) Nees Extract
Target:
Cat. No.: HY-N1490R
CAS No.: 42895-58-9
Synonyms: 14-dehydro Andrographolide (Standard); AP10 (Standard)
Category:
Acanthaceae Extract Plant Terpenoids Diterpenoids Andrographis paniculata (Burm. F.) Nees Extract
Target:
Cat. No.: HY-N15196
CAS No.: 1167601-06-0
Category:
Acanthaceae Extract Natural Products Plant Andrographis paniculata (Burm. F.) Nees Extract
Target:
Cat. No.: HY-N0191S
Synonyms: Andrographis-d
Cat. No.: HY-150587
CAS No.: 3051838-54-8
Research Areas:
Anti-inflammatory agent 31 (enone 17) is a kind of andrographolide derivatives, is a anti-inflammatory agent. Anti-inflammatory agent 31 inhibits NF-κB activation by upstream blockade of PI3K/Akt and ERK1/2 MAPK activation. Anti-inflammatory agent 31 shows recovery effective of the intracellular GSH levels and protective effect on liver .
Cat. No.: HY-N17544
CAS No.: 2079896-37-8
Category:
Acanthaceae Extract Plant Terpenoids Diterpenoids Microorganism Andrographis paniculata (Burm. F.) Nees Extract
Target:
Cat. No.: HY-170921
Target:
Research Areas:
USP1-IN-11 (compound 38-P2) is a selective, reversible, and noncompetitive USP1 (Ubiquitin-specific protease 1) inhibitor. USP1-IN-11 activates the DDR (DNA damage repair) pathway, induces cell cycle arrest and cell Apoptosis, and inhibits cell survival. USP1-IN-11 enhances the sensitivity of Olaparib (HY-10162)-resistant cells to Olaparib (HY-10162) and shows a synergetic effect with Andrographolide (HY-N0191) in BRCA-proficient cancer cells. USP1-IN-11 displays significant, dose-dependent antitumor efficacy in the MDA-MB-436 xenograft model .
Cat. No.: HY-N18740
CAS No.: 90244-84-1
Category:
Target:
Cat. No.: HY-183786
Target:
Research Areas:
Anticancer agent 327, a fluorescent Andrographolide (HY-N0191) derivative, is an NF-κB p50 inhibitor. Anticancer agent 327 covalently binds to the p50 subunit of NF-κB. Anticancer agent 327 reduces levels of multiple oncogenic p53 proteins via the autophagy/lysosome pathway. Anticancer agent 327 can be used for the research of pancreatic ductal adenocarcinoma (Ex/Em = 488/515 nm)[1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
