14 Results for "

Arachidonic acid derivative

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Arachidonic acid derivative" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-78263
CAS No.: 1485-00-3
Synonyms: NSC 170724; 5-(2-Nitrovinyl)benzodioxole
MNS (NSC 170724), the beta-nitrostyrene derivative, is an orally active tyrosine kinase inhibitor, a broad-spectrum antiplatelet agent, and a PANoptosis inhibitor. MNS inhibits Src, Syk, and FAK with IC50 of 27.3, 2.8, and 97.6 μM, respectively. MNS inhibits NLRP3 inflammasome and β1 integrin. MNS completely inhibits U46619, ADP-, arachidonic acid-, collagen-, and thrombin-induced platelet aggregation with IC50 values of 2.1, 4.1, 5.8, 7.0, and 12.7 μM, respectively. MNS is cytotoxic to a variety of cells .
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1
1 Cited Publications
Cat. No.: HY-113331
CAS No.: 54397-85-2
Purity:  ≥99.0%
Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation. Thromboxane B2 is a biological inactive product and circulating catabolite of thromboxane A2. Thromboxane B2 levels in peripheral venous blood and coronary sinus blood can be used as a diagnostic marker for angina. Thromboxane B2 level in serum is also associated with inhibition of COX-1 activity inhibition in platelets. Thromboxane B2 is a major product of prostaglandin endoperoxide metabolism. Thromboxane B2 produces dose-related decreases in airflow rate, tidal volume and dynamic lung compliance, whilst simultaneously increasing pulmonary airway resistance in dog model. Thromboxane B2 appears to be a naturally occurring bronchoactive metabolite in the bioconversion of arachidonic acid .
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Cat. No.: HY-113434B
CAS No.: 71030-39-2
Synonyms: (±)-5-HETE
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM .
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Cat. No.: HY-W047191
CAS No.: 1198-69-2
D-Glucono-1,4-lactone is a derivative of D-gluconic acid (HY-Y0569C). D-Glucono-1,4-lactone can be isolated from fruits, vegetables, honey, kombucha and wine. D-Glucono-1,4-lactone inhibits thrombin-induced arachidonic acid peroxidation and platelet activation. D-Glucono-1,4-lactone reduces superoxide anion production in thrombin-activated platelets. D-Glucono-1,4-lactone exerts antioxidant activity on platelets under oxidative stress conditions and prevents excessive platelet activation through antioxidant mechanisms. D-Glucono-1,4-lactone can be used in research related to cardiovascular diseases .
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Cat. No.: HY-119647
CAS No.: 206052-01-9
Purity:  99.87%
Target:  

COX Cytochrome P450

Research Areas:  

Others

PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC50 values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-19594
CAS No.: 5560-78-1
Synonyms: WIN 13146
Target:  

Parasite

Research Areas:  

Infection

Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections .
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Cat. No.: HY-173534
Synonyms: AA sulfonate sodium
Target:  

Drug Derivative

Research Areas:  

Others

Arachidonic acid sulfonate (AA sulfonate) sodium is a derivative of Arachidonic acid (HY-109590) containing a sulfonate group.
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Cat. No.: HY-119647R
CAS No.: 206052-01-9
Target:  

COX Cytochrome P450

Research Areas:  

Others

PPOH (Standard) is the analytical standard of PPOH. This product is intended for research and analytical applications. PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC50 values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-19594R
CAS No.: 5560-78-1
Synonyms: WIN 13146 (Standard)
Research Areas:  

Infection

Teclozan (Standard) is the analytical standard of Teclozan. This product is intended for research and analytical applications. Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections .
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Cat. No.: HY-114761
CAS No.: 67508-09-2
Research Areas:  

Cardiovascular Disease

Prostaglandin F2α dimethyl amine is a Prostaglandin F2α (HY-12956) derivative. Prostaglandin F2α dimethyl amine is an antagonist for Prostaglandin F receptor (FP) . Prostaglandin F2α dimethyl amine blocks the cardiovascular responses induced by orexin and Arachidonic acid (HY-109590) .
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Cat. No.: HY-N21984
CAS No.: 1932043-30-5
(3S,4S)-4-Hydroxy-3,6-dimethyl-3,4-dihydronaphthalen-1 (2H)-one is a tetralone derivative. (3S,4S)-4-Hydroxy-3,6-dimethyl-3,4-dihydronaphthalen-1 (2H)-one shows weak inhibitory activity against arachidonic acid-induced platelet aggregation, and exhibits no positive inotropic activity at the concentration of 10 -5 g/mL .
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Cat. No.: HY-129470
CAS No.: 61-44-9
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

AQ 1994 hydrochloride is a benzothiophenyl aminoethyl ketone derivative and also a broad-spectrum human platelet aggregation inhibitor. AQ 1994 hydrochloride inhibits human platelet aggregation triggered by 5'-adenosine diphosphate, arachidonic acid, platelet-activating factor, thrombin or collagen. AQ 1994 hydrochloride can be used for thrombosis-related research .
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Cat. No.: HY-170470
CAS No.: 89648-24-8
Synonyms: DG(20:0/20:0/0:0)
Research Areas:  

Others

1,2-Diarachidoyl-rac-glycerol (DG(20:0/20:0/0:0)) is a diacylglycerol in which both acyl groups are acyl groups of arachidonic acid. 1,2-Diarachidoyl-rac-glycerol can be used to enhance the skin barrier function and maintain the moisture and lipid balance of the skin as a diacylglycerol derivative .
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Cat. No.: HY-N21983
CAS No.: 1932291-56-9
(2R,4S)-3,4-Dihydro-4-hydroxy-2,7-dimethyl-1 (2H)-naphthalenone is a tetralone derivative found in Pyrola calliantha. It exerts extremely weak inhibitory effects on arachidonic acid-induced platelet aggregation and shows no positive inotropic activity on isolated guinea pig right atria .
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