46 Results for "

Atrolactamide

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "Atrolactamide" in MCE Product Catalog:

9
9 Publications Verification
製品番号: HY-106178
CAS 番号: 219639-75-5
純度:  99.98%
別名: 3D53
PMX-53 (3D53) is a synthetic peptidic and a potent and orally active complement C5a receptor (CD88) antagonist with an IC50 of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically binds to C5aR1 and does not bind to the second C5aR (C5L2) and C3aR. PMX-53 has anti-inflammatory, anticancer and antiatherosclerotic effects .
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3
3 Cited Publications
製品番号: HY-P0227
CAS 番号: 168482-23-3
Target:  

Melanocortin Receptor

研究分野:  

Metabolic Disease

SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.
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1
1 Cited Publications
製品番号: HY-P0267
CAS 番号: 121062-08-6
Melanotan (MT)-II is a melanocortin receptor agonist. Melanotan (MT)-II activates melanocortin receptor 3 and melanocortin receptor 4, and stimulates the release of central endogenous oxytocin. Melanotan (MT)-II reverses recognition memory impairment, increased anxiety levels and reduced exploratory tendency in zebrafish exposed to short-term high-fat diet. Melanotan (MT)-II improves impaired social behavior indicators in mouse models of autism spectrum disorder. Melanotan (MT)-II induces weight loss, reduces food intake and exerts anorectic effects. Melanotan (MT)-II increases intracavernous pressure and erectile activity in brown rats. Melanotan (MT)-II can be used in studies related to memory impairment, anxiety, reduced exploratory behavior, autism spectrum disorder, obesity and erectile dysfunction .
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1
1 Cited Publications
製品番号: HY-18678A
CAS 番号: 1607799-13-2
別名: PT-141 Acetate
Target:  

Melanocortin Receptor

研究分野:  

Metabolic Disease

Bremelanotide (PT-141) Acetate is a melanocortin receptor agonist. Bremelanotide Acetate can activate MC4R and increases dopamine release. Bremelanotide Acetate induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide Acetate can be used for the research of hypoactive sexual desire disorders .
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1
1 Cited Publications
製品番号: HY-A0248A
CAS 番号: 4135-11-9
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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1
1 Cited Publications
製品番号: HY-P1103
CAS 番号: 1030384-98-5
Target:  

CXCR

研究分野:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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製品番号: HY-145632
CAS 番号: 2538014-94-5
別名: ALT-801
Target:  

GLP Receptor GCGR

研究分野:  

Metabolic Disease

Pemvidutide (ALT-801) is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide can be used in non-alcoholic steatohepatitis (NASH) and obesity research .
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製品番号: HY-P4070
CAS 番号: 1188379-43-2
Target:  

Insulin Receptor

研究分野:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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製品番号: HY-P11290
CAS 番号: 1228015-10-8
Target:  

Melanocortin Receptor

研究分野:  

Metabolic Disease

MC4-NN2-0453, a α-MSH analog, is a selective MC4R agonist. MC4-NN2-0453 can be used for obesity research .
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製品番号: HY-P10447
CAS 番号: 103651-09-8
別名: Fengycin IX; SNA-60-367-3
Target:  

Phospholipase Fungal

研究分野:  

Infection

Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold [1][2].
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製品番号: HY-P1208
CAS 番号: 667430-81-1
Target:  

Melanocortin Receptor

研究分野:  

Inflammation/Immunology

PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R (IC50=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo .
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製品番号: HY-A0248AS
Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
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製品番号: HY-145632A
純度:  98.07%
別名: ALT-801 TFA
Target:  

GLP Receptor GCGR

研究分野:  

Metabolic Disease

Pemvidutide (ALT-801) TFA is a GLP-1R/GCGR dual agonist, shows striking reductions in body weight, liver fat and serum lipids. Pemvidutide TFA can be used in non-alcoholic steatohepatitis (NASH) and obesity research .
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製品番号: HY-P1195
CAS 番号: 1315378-73-4
Target:  

iGluR

研究分野:  

Neurological Disease

PDZ1 Domain inhibitor peptide, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .
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製品番号: HY-P10278
CAS 番号: 133658-45-4
Target:  

ペプチド

研究分野:  

Endocrinology

Anantin binds competitively to the receptor of atrial natriuretic factor (ANF) from bovine adrenal cortex (Kd = 0.6 μM) and acts as natriuretic peptide receptor A antagonist .
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製品番号: HY-P10768A
Target:  

PACAP Receptor

研究分野:  

Inflammation/Immunology

Ro 25-1553 TFA is a 31 amino acid vasoactive intestinal peptide (VIP) analog, that acts as an agonist for VIP2 receptor (VPAC2 receptor). Ro 25-1553 TFA exhibits a bronchodilator effect in nerve-induced or Carbachol (HY-B1208)-induced tracheal smooth muscle contraction in guinea pig model .
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製品番号: HY-P3100
CAS 番号: 939960-34-6
Target:  

Parasite

研究分野:  

Infection

Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
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製品番号: HY-P1209A
Target:  

Melanocortin Receptor

研究分野:  

Metabolic Disease

PG106 TFA is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50= 210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor .
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製品番号: HY-119915
CAS 番号: 2019-68-3
別名: M-144; Themisone
Target:  

Others

研究分野:  

Neurological Disease

Atrolactamide (M-144) is a potent anticonvulsant. Atrolactamide can be used for the research of epilepsy .
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製品番号: HY-P2064
CAS 番号: 732286-09-8
Target:  

Bacterial

研究分野:  

Infection

Lariatins is a novel anti-mycobacterial peptides with a lasso structure produced by Rhodococcus jostii K01-B0171 .
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