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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
BCC
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "BCC" in MCE Product Catalog:
1
1 Cited Publications
Research Areas:
CUR61414 is a novel, potent and cell permeable Hedgehog signaling pathway inhibitor (IC50 =100-200 nM). CUR61414 is a small-molecule aminoproline class compound and selectively binds to smoothened (Smo) with a Ki value of 44 nM. CUR-61414 can induce apoptosis in cancer cells without affecting neighboring non-tumor cells .
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Cat. No.: HY-NP131
Cat. No.: HY-126202
CAS No.: 903892-99-9
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Cat. No.: HY-124301
CAS No.: 1418291-68-5
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Cat. No.: HY-176246
Antitubercular agent-52 (Compound 7k) is an antitubercular agent targeting Mycobacterium tuberculosis (Mtb). Antitubercular agent-52 selectively inhibits the cytochrome bcc (cyt-bcc) electron transport chain of Mtb and also acts on cytochrome bd (cyt-bd). Antitubercular agent-52 blocks electron transfer and ATP production by interfering with the key energy metabolism pathway of Mtb. Antitubercular agent-52 is promising for research of tuberculosis .
Cat. No.: HY-176762
CAS No.: 67047-17-0
Target:
TOP3B-IN-1 (NSC-260610) is a Topoisomerase IIIβ (TOP3B) inhibitor. TOP3B-IN-1 fails to induce the formation of TOP3B cleavage complexes (TOP3Bccs) with both DNA and RNA, and destabilizes TOP3Bccs. TOP3B-IN-1 can be used as a control compound for the development of inhibitors targeting TOP3B .
Cat. No.: HY-N15678
CAS No.: 52940-12-2
Synonyms: 1,3,6,8-THAQ
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Cat. No.: HY-N15652
CAS No.: 30270-17-8
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Cat. No.: HY-N19150
CAS No.: 2227456-72-4
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Cat. No.: HY-182711
CAS No.: 1379615-30-1
SCR0911 is an inhibitor of mycobacterial cytochrome bcc oxidase and Plasmodium falciparum cytochrome bc1. SCR0911 disrupts oxidative phosphorylation by binding to mycobacterial cytochrome bcc, binds to the Qi site of Plasmodium falciparum cytochrome bc1, inhibits mycobacterial cell growth and ATP synthesis, and exhibits broad-spectrum anti-mycobacterial and anti-malarial activities. SCR0911 can be used in research related to tuberculosis, malaria, and isolated persistent hypermethioninemia (iph) .
Cat. No.: HY-183075
CAS No.: 1648720-01-7
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ND-011458 is an Antibacterial agent, a QcrB inhibitor, and also an inhibitor of cytochrome bcc:aa3 oxidase function. ND-011458 binds to the QcrB subunit of cytochrome bcc:aa3 oxidase. ND-011458 inhibits ATP formation. When used in combination with Clofazimine (HY-B1046), ND-011458 exhibits bactericidal activity against Mycobacterium abscessus. ND-011458 can be used in studies related to Mycobacterium abscessus pulmonary infections .
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Cat. No.: HY-P706187
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BCC7; p53; p53 tumor suppressor; Phosphoprotein p5
Species:
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Cat. No.: HY-P706188
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BCC7; p53; p53 tumor suppressor; Phosphoprotein p5
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
