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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
BMP6
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "BMP6" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-16712
CAS No.: 1627503-67-6
Target:
Research Areas:
LDN-214117 is an orally active ALK2 inhibitor with well-tolerated and good brain penetration. LDN-214117 has a high selectivity and low cytotoxicity for ALK2 with an IC50 value of 24 nM. LDN-214117 also is a specific bone morphogenetic proteins (BMPs) signaling inhibitor and has relatively selective inhibition for BMP6 with an IC50 value of 100 nM. LDN-214117 can be used for the research of fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine glioma (DIPG) .
1
1 Cited Publications
Cat. No.: HY-P700029AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BMP6; VG-1-R; Prev. VGR; VGR-1; VGR1; BMP-6; Vegetal Related Growth Factor (TGFB-Related); IO; VG-1-Related Protein; Bone Morphogenetic Protein 6; BMP6 Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-RS01541
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Research Areas:
BMP6 Human Pre-designed siRNA Set A contains three designed siRNAs for BMP6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24417
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Bmp6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Bmp6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17946
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Bmp6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bmp6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991880
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Research Areas:
Cat. No.: HY-P991637
CAS No.: 2996101-49-4
Synonyms: REGN7999
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Research Areas:
REGN7999 is a monoclonal antibody that inhibits TMPRSS6. REGN7999 inhibits TMPRSS6 activity, preventing Hemojuvelin (HJV) lysis, thereby enhancing BMP6-HJV signaling and increasing serum hepcidin. REGN7999 ameliorates iron overload and impaired erythropoiesis in a β-thalassemia mouse model by inhibiting TMPRSS6 activity. REGN7999 is indicated for research in β-thalassemia .
Cat. No.: HY-P991881
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Cat. No.: HY-118970
CAS No.: 233268-78-5
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Research Areas:
LG190155 is a nonsteroidal vitamin D receptor (VDR) agonist. LG190155 activates VDR in mesenchymal stem cells, thereby upregulating the BMP6-IL6 autocrine axis. Pretreatment of mesenchymal stem cells with LG190155 significantly enhances their ability to induce differentiation of acute myeloid leukemia cells, without inducing hypercalcemia. LG190155 is applicable to research related to acute myeloid leukemia (AML) .
Cat. No.: HY-P990974
CAS No.: 2935496-94-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
