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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
CCL17
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "CCL17" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P71891A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-C motif chemokine; CCL17
1
Synonyms: FLX475
Target:
Research Areas:
Tivumecirnon (FLX475) is an orally active, selective CCR4 antagonist. Tivumecirnon blocks the binding of CCR4 to its ligands, CCL17 and CCL22, thereby reducing Treg infiltration into the tumor microenvironment. Tivumecirnon has antitumor activity .
Cat. No.: HY-176949
CAS No.: 3092076-19-9
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STAT6-IN-10 is a STAT6 (signal transducer and activator of transcription 6) inhibitor with an EC50 of 2 nM. STAT6-IN-10 can inhibit the secretion of CCL17 in human peripheral whole blood. STAT6-IN-10 can be used in the research of dermatological and respiratory system diseases .
Cat. No.: HY-P3982
CAS No.: 960358-79-6
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Cat. No.: HY-175650
CAS No.: 3092076-15-5
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STAT6-IN-9 is a potent STAT6 inhibitor with an EC50 value of 4 nM. STAT6-IN-9 effectively blocks STAT6 activation mediated by the IL-13-IL-13 receptor/IL-4 receptor pathway. STAT6-IN-9 inhibits CCL17 secretion with an IC50 value of 4.6 nM. STAT6-IN-9 can be used to investigate various chronic inflammatory diseases mediated by STAT6, such as allergy, asthma, and chronic obstructive pulmonary disease .
Cat. No.: HY-174766
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Research Areas:
Human CCL17 mRNA encodes the human C-C motif chemokine ligand 17 (CCL17) protein, a cytokine that displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Cat. No.: HY-RS02086
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CCL17 Human Pre-designed siRNA Set A contains three designed siRNAs for CCL17 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16826
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Ccl17 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccl17 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23268
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Ccl17 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccl17 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990982
CAS No.: 2922866-66-6
Synonyms: GSK3858279
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Cat. No.: HY-185144
CAS No.: 3104330-39-1
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CCL17-IN-1 (Compound Ex.132) is a CCL17 secretion inhibitor with an EC50 of 0.2 nM. CCL17-IN-1 can be used in the research of autoimmune diseases, dermatological conditions, and respiratory disorders .
Cat. No.: HY-185145
CAS No.: 3104330-35-7
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CCL17-IN-2 (Compound Ex.128) is a CCL17 secretion inhibitor with an EC50 of 0.3 nM. CCL17-IN-1 can be used in the research of autoimmune diseases, dermatological conditions, and respiratory disorders .
Cat. No.: HY-P74532
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-C motif chemokine 17; CCL17; SCYA17; TARC
Species:
Source:
Cat. No.: HY-P74531
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C-C motif chemokine 17; CCL17; SCYA17; TARC
Species:
Source:
Cat. No.: HY-P76667
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-C motif chemokine 17; CCL17; SCYA17; TARC
Species:
Source:
Cat. No.: HY-P992378
Research Areas:
Cat. No.: HY-182564
CAS No.: 618865-88-6
ST45177901 is a CC chemokine receptor 4 (CCR4) antagonist. The combination of ST45177901 and Sorafenib (HY-10201) effectively inhibits the chemotaxis of Treg cells via the CCL22/CCL17-CCR4 signaling pathway, thereby significantly suppressing the growth and metastasis of tumor cells. ST45177901 is applicable to liver cancer research .
Cat. No.: HY-119050
CAS No.: 749860-43-3
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Anti-inflammatory agent 87 (compound 72) is a potential anti-inflammatory agent, whose precursor is an inhibitor targeting the binding of thymus and activation-regulated chemokine (TARC/CCL17) to Hut78 cells. Anti-inflammatory agent 87 can be used in the research of allergic diseases, autoimmune diseases, transplant rejection and other conditions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
