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Results for "

CCL17

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Calcium Channel (1) CCR (9) Fc Receptor (FcR) (1) Interleukin Related (3) mRNA (1) Small Interfering RNA (siRNA) (3) STAT (4)
By Research Areas:	Cancer (2) Inflammation/Immunology (12)
Oligonucleotides:	Chemokine & Receptors (1) Rat Pre-designed siRNA Sets (1) mRNA (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148494

Tivumecirnon FLX475	CCR	Inflammation/Immunology Cancer
Tivumecirnon (FLX475) is an orally active, selective CCR4 antagonist. Tivumecirnon blocks the binding of CCR4 to its ligands, *CCL17* and CCL22, thereby reducing Treg infiltration into the tumor microenvironment. Tivumecirnon has antitumor activity .

HY-176949

STAT6-IN-10	STAT	Inflammation/Immunology
STAT6-IN-10 is a STAT6 (signal transducer and activator of transcription 6) inhibitor with an EC₅₀ of 2 nM. STAT6-IN-10 can inhibit the secretion of CCL17 in human peripheral whole blood. STAT6-IN-10 can be used in the research of dermatological and respiratory system diseases .

HY-P3982

CKLF1-C19	CCR	Inflammation/Immunology
CKLF1-C19 is the C-terminal peptide of human chemokine-like factor 1 (CKLF1). CKLF1-C19 interacts with CCR4, and inhibits chemotaxis induced by both CKLF1 and CCL17. CKLF1-C19 can suppress allergic lung inflammation via inhibiting chemotaxis mediated by CCR3 and CCR4 .

HY-175650

STAT6-IN-9	STAT Interleukin Related	Inflammation/Immunology
STAT6-IN-9 is a potent STAT6 inhibitor with an EC₅₀ value of 4 nM. STAT6-IN-9 effectively blocks STAT6 activation mediated by the IL-13-IL-13 receptor/IL-4 receptor pathway. STAT6-IN-9 inhibits *CCL17* secretion with an IC₅₀ value of 4.6 nM. STAT6-IN-9 can be used to investigate various chronic inflammatory diseases mediated by STAT6, such as allergy, asthma, and chronic obstructive pulmonary disease .

HY-174766

*Human CCL17* mRNA**	mRNA	Inflammation/Immunology
Human CCL17 mRNA encodes the human C-C motif chemokine ligand 17 (CCL17) protein, a cytokine that displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

HY-RS02086

CCL17 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CCL17 Human Pre-designed siRNA Set A contains three designed siRNAs for CCL17 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CCL17 Human Pre-designed siRNA Set A CCL17 Human Pre-designed siRNA Set A

HY-RS16826

Ccl17 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ccl17 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccl17 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccl17 Mouse Pre-designed siRNA Set A Ccl17 Mouse Pre-designed siRNA Set A

HY-RS23268

Ccl17 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ccl17 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccl17 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ccl17 Rat Pre-designed siRNA Set A Ccl17 Rat Pre-designed siRNA Set A

HY-P990982

Denrakibart GSK3858279	CCR	Inflammation/Immunology
HY-P990982 is an *CCL17*-targeting IgG2κ type human antibody, the recommed isotype control is Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-185144

CCL17-IN-1	CCR	Inflammation/Immunology
CCL17-IN-1 (Compound Ex.132) is a *CCL17* secretion inhibitor with an EC₅₀ of 0.2 nM. CCL17-IN-1 can be used in the research of autoimmune diseases, dermatological conditions, and respiratory disorders .

HY-185145

CCL17-IN-2	CCR	Inflammation/Immunology
CCL17-IN-2 (Compound Ex.128) is a *CCL17* secretion inhibitor with an EC₅₀ of 0.3 nM. CCL17-IN-1 can be used in the research of autoimmune diseases, dermatological conditions, and respiratory disorders .

HY-182564

ST45177901	CCR	Cancer
ST45177901 is a CC chemokine receptor 4 (CCR4) antagonist. The combination of ST45177901 and Sorafenib (HY-10201) effectively inhibits the chemotaxis of Treg cells via the CCL22/CCL17-CCR4 signaling pathway, thereby significantly suppressing the growth and metastasis of tumor cells. ST45177901 is applicable to liver cancer research .

HY-119050

Anti-inflammatory agent 87	CCR	Inflammation/Immunology
Anti-inflammatory agent 87 (compound 72) is a potential anti-inflammatory agent, whose precursor is an inhibitor targeting the binding of thymus and activation-regulated chemokine (TARC/CCL17) to Hut78 cells. Anti-inflammatory agent 87 can be used in the research of allergic diseases, autoimmune diseases, transplant rejection and other conditions .

HY-P992474

TAVO101	Interleukin Related STAT CCR Fc Receptor (FcR)	Inflammation/Immunology
TAVO101 is a humanized anti-TSLP antibody with an EC₅₀ of 0.19 nM against hTSLP. TAVO101 inhibits STAT5 activation and *CCL17* release. TAVO101 carries Fc region mutations that enhance its binding to FcRn while reducing its binding to FcγRI, FcγRIIIA and C1q, thereby attenuating effector functions. TAVO101 reduces the levels of inflammatory markers, cell infiltration and histopathological damage in preclinical models of asthma, psoriasis and atopic dermatitis. TAVO101 can be used for research related to asthma, psoriasis and atopic dermatitis .

HY-185073

STAT6-IN-11	STAT	Inflammation/Immunology
STAT6-IN-11 (example 3) is a STAT6 inhibitor with an EC₅₀ of 6 nM. STAT6-IN-11 inhibits CCL17 secretion in peripheral human whole blood, stimulated through the IL-13-IL- 13 receptor/IL-4 receptor pathway, with an IC₅₀ of 83 nM. STAT6-IN-11 can be used for the study of dermatological condition or a respiratory condition .

HY-181006

TSLP modulator-1	Interleukin Related Calcium Channel CCR	Inflammation/Immunology
TSLP modulator-1 (Compound 14O) is a potent TSLP signaling modulator. TSLP modulator-1 exhibits potent inhibition of *CCL17* and IL-1β mRNA expression. TSLP modulator-1 attenuates the protein levels of IL-6, IL-4 and IL-13. TSLP modulator-1 significantly attenuates calcium influx. TSLP modulator-1 exerts anti-inflammatory effects. TSLP modulator-1 effectively alleviates pruritus and atopic dermatitis-like symptoms .

Cat. No.	Product Name	Target	Research Area

HY-P3982

CKLF1-C19	CCR	Inflammation/Immunology
CKLF1-C19 is the C-terminal peptide of human chemokine-like factor 1 (CKLF1). CKLF1-C19 interacts with CCR4, and inhibits chemotaxis induced by both CKLF1 and CCL17. CKLF1-C19 can suppress allergic lung inflammation via inhibiting chemotaxis mediated by CCR3 and CCR4 .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990982

Denrakibart GSK3858279	CCR	Inflammation/Immunology
HY-P990982 is an *CCL17*-targeting IgG2κ type human antibody, the recommed isotype control is Human IgG2 kappa, Isotype Control (HY-P99002) .

HY-P992474

TAVO101	Interleukin Related STAT CCR Fc Receptor (FcR)	Inflammation/Immunology
TAVO101 is a humanized anti-TSLP antibody with an EC₅₀ of 0.19 nM against hTSLP. TAVO101 inhibits STAT5 activation and *CCL17* release. TAVO101 carries Fc region mutations that enhance its binding to FcRn while reducing its binding to FcγRI, FcγRIIIA and C1q, thereby attenuating effector functions. TAVO101 reduces the levels of inflammatory markers, cell infiltration and histopathological damage in preclinical models of asthma, psoriasis and atopic dermatitis. TAVO101 can be used for research related to asthma, psoriasis and atopic dermatitis .

Recombinant Proteins Recommended:

CCL17

Species:	Human (5) Rhesus Macaque (1) Mouse (2) Rat (1) Dog (2)
Tag:	His (7) Tag Free (3) Avi (1) MBP (1) Fc (1)
Source:	HEK293 (3) Sf9 insect cells (3) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71891A

	*TARC/CCL17* Protein, Mouse (His)** 1 Publications Verification C-C motif chemokine; CCL17	Mouse	E. coli
	The TARC/CCL17 protein selectively attracts T lymphocytes, especially Th2 cells, emphasizing its critical role in inflammation and immunity.TARC/CCL17 binds to CCR4 on the surface of T cells, orchestrates immune responses, and contributes to GM-CSF/CSF2-driven pain and inflammation.TARC/CCL17 Protein, Mouse (His) is the recombinant mouse-derived TARC/CCL17 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P71902

	*TARC/CCL17* Protein, Rat (His)** C-C motif chemokine; CCL17	Rat	E. coli
	CCL17 protein is a chemokine with selective chemotactic activity towards Th2 cells and plays a crucial role in various inflammatory and immune processes. It coordinates immune responses by binding to CCR4 on the surface of T cells. TARC/CCL17 Protein, Rat (His) is the recombinant rat-derived TARC/CCL17 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P74532

	*TARC/CCL17* Protein, Human (sf9)** C-C motif chemokine 17; CCL17; SCYA17; TARC	Human	Sf9 insect cells
	TARC/CCL17 Protein, Human (sf9) is the first CC chemokine identified to interact with T cells with high affinity and bind to the CCR4 receptor to mediate inflammation, cancer, and autoimmune related diseases. TARC/CCL17 Protein, Human (sf9) is a recombinant human TARC/CCL17(M1-S94) protein expressed by Sf9 insect cells.

HY-P74531

	*TARC/CCL17* Protein, Human (sf9, His)** C-C motif chemokine 17; CCL17; SCYA17; TARC	Human	Sf9 insect cells
	TARC/CCL17 Protein, Human (sf9, His) is the first CC chemokine identified to interact with T cells with high affinity and bind to the CCR4 receptor to mediate inflammation, cancer, and autoimmune related diseases. TARC/CCL17 Protein, Human (sf9, His) is a recombinant human TARC/CCL17(M1-S94) protein expressed by Sf9 insect cells with a his tag at C end.

HY-P76667

	*TARC/CCL17* Protein, Rhesus Macaque (sf9, His)** C-C motif chemokine 17; CCL17; SCYA17; TARC	Rhesus Macaque	Sf9 insect cells
	TARC/CCL17 Protein,Rhesus Macaque (sf9, His) is the first CC chemokine identified to interact with T cells with high affinity and bind to the CCR4 receptor to mediate inflammation, cancer, and autoimmune related diseases. TARC/CCL17 Protein,Rhesus Macaque (sf9, His) is a recombinant rhesus macaque TARC/CCL17(M1-S94) protein expressed by Sf9 insect cells with his tag at C end.

HY-P7759

	*TARC/CCL17* Protein, Human (HEK293, His)** 1 Publications Verification rHuCCL17, His; C-C motif chemokine 17; CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine; CCL17; SCYA17; TARC	Human	HEK293
	TARC/CCL17 Protein, Human (HEK293, His) is the first CC chemokine identified to interact with T cells with high affinity and bind to the CCR4 receptor to mediate inflammation, cancer, and autoimmune related diseases. TARC/CCL17 Protein, Human (HEK293, His) is a recombinant human TARC/CCL17(A24-S94) protein expressed by HEK293 with a his tag at C end.

HY-P7292

	*TARC/CCL17* Protein, Human** rHuTARC/CCL17; C-C motif chemokine 17; SCYA17	Human	E. coli
	TARC/CCL17 Protein, Human is the first CC chemokine identified to interact with T cells with high affinity and bind to the CCR4 receptor to mediate inflammation, cancer, and autoimmune related diseases. TARC/CCL17 Protein, Human is a recombinant human TARC/CCL17 (A24-S94) protein expressed by E. coli.

HY-P7293

	*TARC/CCL17* Protein, Mouse (70a.a)** rMuTARC/CCL17; C-C motif chemokine 17; SCYA17	Mouse	E. coli
	TARC/CCL17 Protein, Mouse (70a.a) is the first CC chemokine identified to interact with T cells with high affinity and bind to the CCR4 receptor to mediate inflammation, cancer, and autoimmune related diseases. TARC/CCL17 Protein, Mouse is a recombinant mouse TARC/CCL17(A34-P103) protein expressed by E. coli.

HY-P704902

	*TARC/CCL17* Protein, Human (HEK293, Fc)** rHuTARC/CCL17; C-C motif chemokine 17; SCYA17	Human	HEK293

HY-P700552

	*TARC/CCL17* Protein, Dog (HEK293, His)** rHuTARC/CCL17; C-C motif chemokine 17; SCYA17	Dog	HEK293
	The TARC/CCL17 protein attracts T lymphocytes, particularly Th2 cells, and is involved in inflammation and immunity. It binds to CCR4 on T cells and contributes to GM-CSF/CSF2-induced pain and inflammation. In the brain, it maintains hippocampal microglia morphology and aids in adapting to neuroinflammation. Additionally, it plays a role in wound healing by promoting fibroblast migration. TARC/CCL17 Protein, Dog (HEK293, His) is the recombinant dog-derived TARC/CCL17 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P702846

	*TARC/CCL17* Protein, Dog (Biotinylated, MBP, His-Avi)** rHuTARC/CCL17; C-C motif chemokine 17; SCYA17	Dog	E. coli
	The TARC/CCL17 protein attracts T lymphocytes, particularly Th2 cells, and is involved in inflammation and immunity. It binds to CCR4 on T cells and contributes to GM-CSF/CSF2-induced pain and inflammation. In the brain, it maintains hippocampal microglia morphology and aids in adapting to neuroinflammation. Additionally, it plays a role in wound healing by promoting fibroblast migration. TARC/CCL17 Protein, Dog (Biotinylated, MBP, His-Avi) is the recombinant dog-derived TARC/CCL17 protein, expressed by E. coli , with N-MBP, C-6*His-Avi labeled tag.

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Host:	Rabbit (3)
Reactivity:	Human (3) Mouse (1)
Application:	IHC-P (3) WB (1)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3) Biotin (1)
Clonality:	polyclonal (1) Monoclonal (1) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81466

	*TARC/CCL17* Antibody (YA1211)** TARC; CCL17; SCYA17; C-C motif chemokine 17; C-C motif chemokine 17; Small-inducible cytokine A17; Thymus and activation-regulated chemokine	IHC-P	Human
	TARC/CCL17 Antibody (YA1211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TARC/CCL17.

HY-P81466A

	*TARC/CCL17* Antibody (YA1211)(PBS only)** TARC; CCL17; SCYA17; C-C motif chemokine 17; C-C motif chemokine 17; Small-inducible cytokine A17; Thymus and activation-regulated chemokine	IHC-P	Human
	TARC/CCL17 Antibody (YA1211) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TARC/CCL17.

HY-P810501

	*TARC/CCL17* Antibody**	WB, IHC-P	Human, Mouse
	TARC/CCL17 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to TARC/CCL17.