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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
CD155
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "CD155" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-162080
CAS No.: 374705-10-9
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METTL1-WDR4-IN-1 (Compound 1) is a selective competitive inhibitor of the methyltransferase complex METTL1-WDR4 (IC50 = 144 μM). METTL1-WDR4-IN-1 inhibits the m 7G methyltransferase activity of the METTL1-WDR4 complex, blocking m 7G modification of PKM mRNA, reducing PKM2 protein expression, disrupting the METTL1/PKM2/H3K9la positive feedback loop, and simultaneously inhibiting PKM2 nuclear translocation-mediated CD155 transcriptional activation. METTL1-WDR4-IN-1 can inhibit tumor cell proliferation, weaken glycolytic metabolism, reverse tumor immune evasion (restoring NK cell and CD8 + T cell function), and regulate RNA epigenetic modification and the tumor immune microenvironment. METTL1-WDR4-IN-1 can be used in immunotherapy research for cancers such as colorectal cancer, and is particularly suitable for use in combination with PKM2 inhibitors to enhance anti-tumor treatment efficacy .
2
2 Cited Publications
Cat. No.: HY-162080A
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METTL1-WDR4-IN-1 (Compound 1) TFA is a selective competitive inhibitor of the methyltransferase complex METTL1-WDR4 (IC50=144 μM). METTL1-WDR4-IN-1 TFA inhibits the m 7G methyltransferase activity of the METTL1-WDR4 complex, blocking the m 7G modification of PKM mRNA, reducing PKM2 protein expression, disrupting the METTL1/PKM2/H3K9la positive feedback loop, and simultaneously inhibiting PKM2 nuclear translocation-mediated CD155 transcriptional activation. METTL1-WDR4-IN-1 TFA can inhibit tumor cell proliferation, weaken glycolytic metabolism, reverse tumor immune evasion (restoring NK cell and CD8 + T cell function), and regulate RNA epigenetic modification and the tumor immune microenvironment. METTL1-WDR4-IN-1 TFA can be used in immunotherapy research for cancers such as colorectal cancer, and is particularly suitable for use in combination with PKM2 inhibitors to enhance anti-tumor treatment efficacy .
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Cat. No.: HY-P990155
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Cat. No.: HY-P99858
CAS No.: 2368219-35-4
Synonyms: AB154
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Cat. No.: HY-P990641
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Cat. No.: HY-P99949
CAS No.: 2044984-83-8
Synonyms: OMP-313M32
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Cat. No.: HY-P991798
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Cat. No.: HY-P990259
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Cat. No.: HY-P990031
CAS No.: 2649362-29-6
Synonyms: M-6223
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Cat. No.: HY-P991620
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Cat. No.: HY-RS16791
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Pvr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pvr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704254
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuCD155, His; Poliovirus receptor; CD155 antigen; Nectin-like protein 5; Nectin-2; Tage4 receptor; PVR; CD155
Cat. No.: HY-P7790
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rRhCD155, His; Poliovirus receptor; CD155 antigen; Nectin-like protein 5; Nectin-2; Tage4 receptor; PVR; CD155
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Cat. No.: HY-P705285
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rRhCD155, His; Poliovirus receptor; CD155 antigen; Nectin-like protein 5; Nectin-2; Tage4 receptor; PVR; CD155
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Cat. No.: HY-P705248
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PVR; FLJ25946; PVS; CD155; TAGE4; HVED; NECL5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
