32 Results for "

CD79B

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "CD79B" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99042
CAS No.: 2279068-37-8
Polatuzumab is a monoclonal antibody that targets CD79b on the surface of B cells. Polatuzumab can be used to synthesize the ADC Polatuzumab Vedotin (HY-132253), which has anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-132253
CAS No.: 1313206-42-6
Purity:  98.83%
Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin has the potential for the research of Large B-cell lymphomas (LBCL) .
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1
1 Cited Publications
Cat. No.: HY-132253A
CAS No.: 1313206-42-6
Purity:  98.36%
Polatuzumab vedotin solution is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin solution has the potential for the research of Large B-cell lymphomas (LBCL) .
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Cat. No.: HY-157763
Research Areas:  

Cancer

Mal-PEG1-Val-Cit-PABC-diphosphate-BTK degrader-1 is a cleavable linker-payload conjugate and cereblon-binding BTK bifunctional degrader. Mal-PEG1-Val-Cit-PABC-diphosphate-BTK degrader-1 induces BTK degradation and exerts cytotoxic effects when delivered via CD79b monoclonal antibody. Mal-PEG1-Val-Cit-PABC-diphosphate-BTK degrader-1, when formulated as a CD79b antibody-drug conjugate, achieves sustained in vivo BTK degradation in tumor-bearing mice with reduced systemic payload exposure. Mal-PEG1-Val-Cit-PABC-diphosphate-BTK degrader-1 can be used for the research of activated b-cell-like diffuse large b-cell lymphoma (ADC linker: (HY-130944); PROTAC: (HY-163295)) .
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Cat. No.: HY-P99656
CAS No.: 1906205-76-2
Synonyms: MCDS0593A

Target:  

ADC Antibodies

Research Areas:  

Cancer

Iladatuzumab (MCDS0593A) is a humanized IgG1 anti-human CD79B monoclonal antibody. Iladatuzumab can be used to synthesize antibody-drug conjugates (ADC) Iladatuzumab vedotin (DCDS0780A; HY-P99657), which has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research .
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Cat. No.: HY-P991086
Synonyms: PRV-3279

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

MGD010 (PRV-3279) is a bispecific antibody targeting CD32B (FcγRIIb) and CD79B. MGD010 transmits negative signals by simultaneously co-linking CD32B (FcγRIIb) with CD79B, a component of the B-cell receptor (BCR), thereby inhibiting activated B cells. MGD010 can be used in research related to autoimmune diseases .
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Cat. No.: HY-163295
CAS No.: 2377645-56-0
Target:  

ADC Payloads Btk

Research Areas:  

Cancer

BTK degrader-1 (compound 1) is a Bruton’s tyrosine kinase (BTK) bifunctional degrader that can be conjugated with CD79b. BTK degrader-1 (compound 1) has anti-tumor effect .
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Cat. No.: HY-RS02268
Research Areas:  

Others

CD79B Human Pre-designed siRNA Set A contains three designed siRNAs for CD79B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17825
Research Areas:  

Others

Cd79b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd79b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24293
Research Areas:  

Others

Cd79b Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd79b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991671
CAS No.: 3009026-69-8
Synonyms: JNJ-80948543

Research Areas:  

Cancer

Anafiltamig is a trivalent monoclonal antibody inhibitor targeting CD79B, CD3E and MS4A1. Anafiltamig consists of a humanized IgG1κ anti-CD79B arm and a bispecific scFv-based arm targeting CD3E and MS4A1. Anafiltamig simultaneously bridges T and B cells, activating T cells and specifically killing B cell tumors. Anafiltamig can be used for B cell malignancies such as non-Hodgkin lymphoma research .
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Cat. No.: HY-P991804

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD79b Antibody (HM79b) reacts with the mouse CD79b. CD79b participates in the signal transduction cascade activated by the B cell antigen receptor complex (BCR), ultimately leading to complex internalization, transport to late endosomes, and antigen presentation. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978) .
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Cat. No.: HY-P85008
Synonyms: CD79B; B29; IGB; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD79B; CD79B nanobody;

Host:  

Mouse

Application:  

ELISA, FC

Reactivity:  

Human

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Cat. No.: HY-P78415
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: B29; CD79B molecule; CD79B; IGB; IGBAGM6; Ig-beta; Ig-β
Species:  
Source:  
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Cat. No.: HY-P78263
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: B29; CD79B molecule; CD79B; IGB; IGBAGM6; Ig-beta; Ig-β
Species:  
Source:  
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Cat. No.: HY-P78901
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD79B; B29; IGB; Ig-beta
Species:  
Source:  
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Cat. No.: HY-P704492
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: B-Cell Antigen Receptor Complex-Associated Protein Beta Chain; B-Cell-Specific Glycoprotein B29; Ig-Beta; Immunoglobulin-Associated B29 Protein; CD79B; CD79B; B29; IGB
Species:  
Source:  
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Cat. No.: HY-P70541
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: B-Cell Antigen Receptor Complex-Associated Protein Beta Chain; B-Cell-Specific Glycoprotein B29; Ig-Beta; Immunoglobulin-Associated B29 Protein; CD79B; CD79B; B29; IGB
Species:  
Source:  
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Cat. No.: HY-P70768
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: B-Cell Antigen Receptor Complex-Associated Protein Beta Chain; B-Cell-Specific Glycoprotein B29; Ig-Beta; Immunoglobulin-Associated B29 Protein; CD79B; CD79B; B29; IGB
Species:  
Source:  
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Cat. No.: HY-P81383
Synonyms: CD79B; AGM6; B29; IGB

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Mouse, Rat

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