2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation
  3. Antibody-Drug Conjugates (ADCs) Transmembrane Glycoprotein
  4. Polatuzumab vedotin (solution)

Polatuzumab vedotin solution is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin solution has the potential for the research of Large B-cell lymphomas (LBCL).

For research use only. We do not sell to patients.

Polatuzumab vedotin (solution)

Polatuzumab vedotin (solution) Chemical Structure

CAS No. : 1313206-42-6

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Based on 1 publication(s) in Google Scholar

Other Forms of Polatuzumab vedotin (solution):

Polatuzumab vedotin (solution) Related Antibodies

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Description

Polatuzumab vedotin solution is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin solution has the potential for the research of Large B-cell lymphomas (LBCL)[1].

In Vivo

Polatuzumab vedotin (0.3, 1, 3, 6, 12 mg/kg; i.v.; once) shows anti-tumor in a mouse tumour xenograft model of human diffuse large B-cell lymphoma WSU-DLCL2[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

150000 (average)

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Polatuzumab vedotin (solution)]
Shipping

Shipping with dry ice.
Storage

-80°C, protect from light
Purity & Documentation
References
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Polatuzumab vedotin (solution) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polatuzumab vedotin (solution)1313206-42-6Antibody-Drug Conjugates (ADCs)Transmembrane GlycoproteinAntibody-Drug Conjugatesantibody-drugLarge B-cell lymphomasanti-tumorInhibitorinhibitorinhibit

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