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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
CLA
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "CLA" in MCE Product Catalog:
Cat. No.: HY-W127851
CAS No.: 19953-58-3
Synonyms: Cypridina luciferin analog
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1
1 Cited Publications
Synonyms: trans-10,cis-12 CLA2
Research Areas:
(10E,12Z)-Octadeca-10,12-dienoic acid (trans-10,cis-12 CLA2) is an orally active PPARα activator and inhibits adipocyte differentiation. (10E,12Z)-Octadeca-10,12-dienoic acid and its downstream metabolites have various antioxidant and antitumor activities. (10E,12Z)-Octadeca-10,12-dienoic acid can induce proinflammatory cytokines and chemokines, which would lead to decreased adipogenesis and insulin resistance in adipose tissue. (10E,12Z)-Octadeca-10,12-dienoic acid can affect many aspects of milk fat synthesis. (10E,12Z)-Octadeca-10,12-dienoic acid reduces expression of lipogenic enzymes and inhibits the desaturation of fatty acids. (10E,12Z)-Octadeca-10,12-dienoic acid can reduce lipoprotein lipase (LPL) activity in cultured 3T3-L1 adipocytes and enhance triacylglycerol release from these cells. (10E,12Z)-Octadeca-10,12-dienoic acid decreases the expression of hepatic stearoyl-CoA desatyrase mRNA in mice. (10E,12Z)-Octadeca-10,12-dienoic acid is associated with changes in mucosal NF-κB and Cyclin D1 protein levels in mice .
Synonyms: 9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2
Target:
Research Areas:
9 (Z),11 (E)-Conjugated linoleic acid methyl ester (9Z,11E-CLA; Methyl 9 (Z),11 (E)-octadecadienoate; (9Z,11E)-SFE 19:2) is an isomer of Linoleic acid (HY-N0729), and is a conjugated linoleic acid mainly found in meat and dairy products. Conjugated linoleic acid is a bioactive fatty acid that improves body composition, enhances immune system function, and exhibits anti-cancer and anti-atherosclerotic effects .
Synonyms: t9,t11-CLA
Target:
Research Areas:
9(E),11(E)-Octadecadienoic acid is an isomer of conjugated linoleic acid (CLA). Conjugated linoleic acid is a fatty acid with potentially beneficial physiological and anticarcinogenic effects .
Cat. No.: HY-116768
CAS No.: 21870-97-3
Synonyms: 10E,12Z-CLA Methyl ester; Methyl 10(E),12(Z)-octadecadienoate methyl ester; (10E,12Z)-SFE 19:2
Target:
Research Areas:
10(E),12(Z)-Conjugated linoleic acid methyl ester (10E,12Z-CLA Methyl ester; Methyl 10(E),12(Z)-octadecadienoate methyl ester; SFE 19:2) is derivative of conjugated linoleic acid. 10(E),12(Z)-Conjugated linoleic acid methyl ester is utilized in the quantification of 10(E),12(Z)-conjugated linoleic acid .
Cat. No.: HY-168616
CAS No.: 2763661-39-6
CL-A3-7 is a virus-cell fusion inhibitor targeting the RSV F protein. It exerts its effect by blocking the interaction between the virus and the host IGF1R, effectively inhibiting infections of both wild-type RSV and the K394R variant. It is applicable to anti-RSV drug development and resistance-related research .
Cat. No.: HY-113427S
Cat. No.: HY-W127852
CAS No.: 886840-56-8
Cat. No.: HY-138896
CAS No.: 1417651-32-1
Synonyms: 9E,11E-9-Nitro CLA
Target:
Research Areas:
(9E,11E)-9-Nitro-9,11-octadecadienoic acid (9E,11E-9-Nitro CLA) is a nitro-fatty acid, It is formed by exposure of 9Z, 11E-CLA to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite .
Cat. No.: HY-166256
CAS No.: 330214-86-3
Synonyms: Ethyl (9Z,11E)-9,11-octadecadienoate
Target:
Research Areas:
CLA 9c,11tr ethyl ester (Ethyl (9Z,11E)-9,11-octadecadienoate) is an ester product.
Cat. No.: HY-123125
CAS No.: 195131-60-3
Target:
Research Areas:
GW9820 is PPARα and PPARγ activator (EC50s: 0.37 μM for PPARα; 0.288 μM for PPARγ). GW9820 increases CLA-1. GW9820 can be used in the research of atherosclerosis .
Cat. No.: HY-RS12648
Target:
Research Areas:
SELPLG Human Pre-designed siRNA Set A contains three designed siRNAs for SELPLG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-113427R
CAS No.: 693-72-1
Cat. No.: HY-173518
CAS No.: 3064262-80-9
Research Areas:
SIN 14, a derivative of Sinomenine (HY-15122), is an orally active HO-1 activator (KD = 17.2 μM). SIN 14 binds to the catalytic core domain of HO-1 and induces HO-1 activation in catalysis. SIN 14 significantly increases HO-1 stability. SIN 14 has anti-inflammatory effects and inhibits M1 macrophage polarization while promoting M2 polarization in LPS (Lipopolysaccharides)(HY-D1056)-induced RAW264.7 cells. SIN 14 inhibits inflammatory mediator production (eg: NO, IL-6, IL-1β and CCL2, inhibits production of ROS and down-regulates the expression of COX-2 and iNOS. SIN 14 can inhibit RA-related inflammatory edema in collagen-induced arthritis (ClA) mice .
Cat. No.: HY-166254
CAS No.: 330214-87-4
Synonyms: Ethyl (10E,12Z)-10,12-octadecadienoate
Target:
Research Areas:
CLA 10(E),12(Z) ethyl ester (Ethyl (10E,12Z)-10,12-octadecadienoate) is an ester product.
Cat. No.: HY-P700815
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SELPLG; Cutaneous Lymphocyte-Associated Associated Antigen; Selectin P Ligand; CD162 Antigen; PSGL-1; PSGL1; CD162; CLA; P-Selectin Glycoprotein Ligand 1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
