46 Results for "

CS-1

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "CS-1" in MCE Product Catalog:

34
34 Publications Verification
Cat. No.: HY-141511
CAS No.: 874748-20-6
Purity:  97.74%
Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases [1].
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6
6 Cited Publications
Cat. No.: HY-B1692
CAS No.: 15985-39-4
Synonyms: MSX; MSO
Target:  

Glutaminase

Research Areas:  

Neurological Disease

L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) .
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4
4 Cited Publications
Cat. No.: HY-16276
CAS No.: 928134-65-0
Synonyms: LCI699
Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS) .
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4
4 Cited Publications
Cat. No.: HY-16276A
CAS No.: 1315449-72-9
Synonyms: LCI699 phosphate
Research Areas:  

Cardiovascular Disease Cancer

Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) .
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Cat. No.: HY-12515CS1
Purity:  ≥99.0%
Synonyms: (R)-YC-93-d3 free base
(R)-Nicardipine-d3 is the deuterium labeled R-Nicardipine (HY-12515C) [1].
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Cat. No.: HY-106950CS1
Synonyms: Diphosphofructose-2-13C sodium; Esafosfan-2-13C sodium; FDP-2-13C sodium
Fosfructose-2- 13C (sodium) is the 13C labeled Fosfructose [1].
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Cat. No.: HY-B0311CS1
CAS No.: 1185134-76-2
(Rac)-Carbidopa-d5 is a deuterium labeled compound.
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Cat. No.: HY-43962
CAS No.: 693227-00-8
Synonyms: Androgen receptor ligand 3
CS-1-65 is an androgen receptor (AR) ligand. CS-1-65 is linked to an IAP ligand via a linker to form an ERα PROTAC degrader.
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Cat. No.: HY-137005
CAS No.: 1448009-94-6
Target:  

Topoisomerase Apoptosis

Research Areas:  

Cancer

CS1 is a potent DNA Topo II α inhibitor. CS1 displays broad-spectrum in vitro antitumor effects, low toxicity in vivo and potential anti-multidrug resistance capabilities. CS1 leads to DNA damage, cell cycle arrest at G2/M phase and apoptosis [1].
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Cat. No.: HY-P1816
CAS No.: 136466-51-8
Target:  

Integrin

Research Areas:  

Cancer

The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models [1].
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Cat. No.: HY-179238
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

CS-1-103 is a potent estrogen receptor (ER) TRACER (transcriptional regulation via active control of epigenetic reprogramming). CS-1-103 inhibits ER transcriptional activity with an EC50 of 0.36 μM by recruiting methyl-CpG binding domain protein 2 (MBD2), HDACs and the nucleosome remodeling and deacetylase (NuRD) complex. CS-1-103 can be used for breast and prostate cancer research [1].
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Cat. No.: HY-P990644

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

PDL-241 is a humanized antibody expressed in CHO that targets SLAMF7/CS1. PDL-241 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.38 kDa. The isotype control for PDL-241 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P84817
Synonyms: 19A; CS1; SLAMF7; CRACC

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat, Monkey, Rabbit

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Cat. No.: HY-RS06994
Research Areas:  

Others

ITPRID2 Human Pre-designed siRNA Set A contains three designed siRNAs for ITPRID2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23100
Research Areas:  

Others

Cat Rat Pre-designed siRNA Set A contains three designed siRNAs for Cat gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P84817A
Synonyms: 19A; CS1; SLAMF7; CRACC

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat, Monkey, Rabbit

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Cat. No.: HY-RS08966
Research Areas:  

Others

MYOZ2 Human Pre-designed siRNA Set A contains three designed siRNAs for MYOZ2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS12981
Research Areas:  

Others

SLAMF7 Human Pre-designed siRNA Set A contains three designed siRNAs for SLAMF7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16665
Research Areas:  

Others

Cat Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cat gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS03236
Research Areas:  

Others

CSH1 Human Pre-designed siRNA Set A contains three designed siRNAs for CSH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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