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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
CSE
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "CSE" in MCE Product Catalog:
5
Research Areas:
Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively . Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase . Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis . Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway . Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM . Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC50 of 0.47 µM .
1
1 Cited Publications
Target:
Research Areas:
Cystathionine-γ-lyase-IN-1 is a selective cystathionine γ-lyase (CSE) enzyme inhibitor with an IC50 of 6.3 μM . Cystathionine-γ-lyase-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
1 Cited Publications
Target:
Research Areas:
Chst15-IN-1 is a potent reversible covalent Chst15 inhibitor. Chst15-IN-1 effectively inhibits chondroitin sulfate-E (CS-E) sulfation levels and other closely related glycosaminoglycans (GAG) sulfotransferases. Chst15-IN-1, as a selective sulfotransferase inhibitor, can diminish the inhibitory effects of chondroitin sulfate proteoglycans (CSPGs), and can be used for the stimulation of neuronal repair .
1
1 Cited Publications
Cat. No.: HY-P70025
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTH; Cysteine Desulfhydrase; Cystathionine Gamma-Lyase; Gamma-Cystathionase; CSE; CGL; Cystathionase (Cystathionine Gamma-Lyase); Homoserine Dehydratase; Cysteine-Protein Sulfhydrase; Homoserine Deaminase; Homocysteine Desulfhydrase
Species:
Human
Source:
E. coli
Category:
Flavonoids Zingiberaceae Extract Flavones Metabolic Disease Plants Disease Research Fields
Target:
Cat. No.: HY-N14001
CAS No.: 2227550-73-2
Cat. No.: HY-169212
CAS No.: 445238-07-3
I194496 is a potent cystathionine γ-lyase (CSE) inhibitor, with an IC50 of 0.79 mM. I194496 can inhibit the growth of human TNBC cells via the dual targeting PI3K/Akt and Ras/Raf/ERK pathway and suppress the metastasis of human TNBC cells via down-regulating Anxa2/STAT3 and VEGF/FAK/Paxillin signaling pathways .
Cat. No.: HY-W051612
CAS No.: 16900-57-5
DL-Propargylglycine hydrochloride is an irreversible and selective CSE inhibitor that blocks the biosynthesis of endogenous hydrogen sulfide. DL-Propargylglycine hydrochloride induces ROS and TGF-β1 expression. DL-Propargylglycine hydrochloride downregulates carotid ACE2 and Ang-(1-7), and elevates Ang II. DL-Propargylglycine hydrochloride upregulates ICAM-1/LFA-1, exacerbating Aspirin (HY-14654)-induced gastric mucosal injury. DL-Propargylglycine hydrochloride is used in research on diabetes-induced liver injury, diabetic nephropathy, atherosclerosis, gastric mucosal injury, hemorrhagic shock, and Streptococcus agalactiae infection .
Category:
Target:
Cat. No.: HY-RS03226
Target:
Research Areas:
CSE1L Human Pre-designed siRNA Set A contains three designed siRNAs for CSE1L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03296
Target:
Research Areas:
CTH Human Pre-designed siRNA Set A contains three designed siRNAs for CTH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23715
Target:
Research Areas:
Cth Rat Pre-designed siRNA Set A contains three designed siRNAs for Cth gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N6617
CAS No.: 54954-12-0
Category:
Cardiovascular Disease Monophenols Gentianaceae Extract Phenols Gentianella acuta (Michx.) Hulten Plants Disease Research Fields
Target:
Cat. No.: HY-RS13157
Target:
Research Areas:
SLC2A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC2A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W422507
CAS No.: 30845-11-5
Target:
Research Areas:
S-(3-Carboxypropyl)-L-cysteine is a Cystathionine γ-lyase (HY-E70344) (CSE) inhibitor with an IC50 of 71 μM, Ki values of 50 μM and 180 μM, and a Kd of 26 μM against human CSE. It exhibits selectivity for CSE compared to other hydrogen sulfide biosynthesizers. S-(3-Carboxypropyl)-L-cysteine is membrane permeable and inhibits transsulfurization flux in cultured cells .
Cat. No.: HY-RS17261
Target:
Research Areas:
Cth Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cth gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P71309
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIAE; MGC87009; Prev. YSG2; Cytosolic Sialic Acid 9-O-Acetylesterase Homolog; CSE-C; Sialic Acid-Specific 9-O-Acetylesterase; LSE; Ysg2 Homolog (Mouse); Sialic Acid-Specific Acetylesterase II; AIS6; Sialate O-Acetylesterase; CSEC; Sialic Acid Acetylestera
Species:
Human
Source:
HEK293
Cat. No.: HY-P74548
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIAE; MGC87009; Prev. YSG2; Cytosolic Sialic Acid 9-O-Acetylesterase Homolog; CSE-C; Sialic Acid-Specific 9-O-Acetylesterase; LSE; Ysg2 Homolog (Mouse); Sialic Acid-Specific Acetylesterase II; AIS6; Sialate O-Acetylesterase; CSEC; Sialic Acid Acetylestera
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703199
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC2A1; HepG2 Glucose Transporter; Prev. GLUT1; Dystonia Gene 9; Prev. HTLVR; Solute Carrier Family 2, Facilitated Glucose Transporter Member 5; Prev. GLUT; Solute Carrier Family 2 Facilitated Glucose Transporter Member 1; Prev. CSE; Glucose Transporter T
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
