Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
74 Results for "
CXC chemokine receptor
" in MedChemExpress (MCE) Product Catalog:
Products (74)
74 Results for "CXC chemokine receptor" in MCE Product Catalog:
40
40 Publications Verification
Target:
Research Areas:
AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively .
4
4 Cited Publications
Cat. No.: HY-P0172
CAS No.: 1337878-62-2
Target:
Research Areas:
4
4 Cited Publications
Cat. No.: HY-P0172A
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P7131
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL13; C-X-C Motif chemokine 13; Prev. SCYB13; CXC chemokine BLC; BCA-1; BCA1; BLC; B-Cell-Homing chemokine (Ligand For Burkitt'S Lymphoma receptor-1); ANGIE2; chemokine (C-X-C Motif) Ligand 13 (B-Cell Chemoattractant); BLR1L; chemokine (C-X-C Motif) Lig
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P7151
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL16; CXCLG16; C-X-C Motif chemokine Ligand 16; Scavenger receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein; SR-PSOX; chemokine (C-X-C Motif) Ligand 16; SRPSOX; Small-Inducible Cytokine B16; Transmembrane chemokine CXCL16; CXC chemokine Ligand 16; C-X-C Motif chemokine 16; SCYB16
Species:
Mouse
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P77911
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CXCL13; C-X-C Motif chemokine 13; Prev. SCYB13; CXC chemokine BLC; BCA-1; BCA1; BLC; B-Cell-Homing chemokine (Ligand For Burkitt'S Lymphoma receptor-1); ANGIE2; chemokine (C-X-C Motif) Ligand 13 (B-Cell Chemoattractant); BLR1L; chemokine (C-X-C Motif) Lig
Species:
Mouse
Source:
HEK293
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P77912
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CXCL13; C-X-C Motif chemokine 13; Prev. SCYB13; CXC chemokine BLC; BCA-1; BCA1; BLC; B-Cell-Homing chemokine (Ligand For Burkitt'S Lymphoma receptor-1); ANGIE2; chemokine (C-X-C Motif) Ligand 13 (B-Cell Chemoattractant); BLR1L; chemokine (C-X-C Motif) Lig
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72961
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL16; CXCLG16; C-X-C Motif chemokine Ligand 16; Scavenger receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein; SR-PSOX; chemokine (C-X-C Motif) Ligand 16; SRPSOX; Small-Inducible Cytokine B16; Transmembrane chemokine CXCL16; CXC Chemoki
Species:
Human
Source:
HEK293
Synonyms: AZD4721; RIST4721
Target:
Research Areas:
Vimnerixin (AZD4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 (CXCR2). Vimnerixin has the potential for the research of inflammatory disease .
Cat. No.: HY-P3612
CAS No.: 577782-52-6
Target:
Research Areas:
Target:
Research Areas:
CXCR7 modulator 2 is a modulator of C-X-C Chemokine Receptor Type 7 (CXCR7), with a Ki of 13 nM.
Cat. No.: HY-178205
CAS No.: 2236595-58-5
BPRCX 807 is a selective and potent CXCR4 (CXC chemokine receptor type 4) antagonist. BPRCX 807 inhibits CXCL12-mediated ERK and Akt phosphorylation. BPRCX 807 can significantly suppress primary tumor growth. BPRCX 807 can be used for the study of hepatocellular carcinoma .
Cat. No.: HY-162632
CAS No.: 440338-68-1
Research Areas:
Hit 14 is an inhibitor for C-X-C chemokine receptor type 4 (CXCR4) with IC50 of 254 nM. Hit 14 inhibits the migration and invasion of cell MDA-MB-231. Hit 14 inhibits the Akt phosphorylation, exhibits anti-inflammatory activity, and ameliorateds the ear swelling and damage in mouse models .
Cat. No.: HY-P4109
CAS No.: 265650-93-9
Synonyms: NT21MP; V1 peptide
Target:
Research Areas:
Cat. No.: HY-174728
Target:
Research Areas:
Human CXCR1 mRNA encodes the human C-X-C motif chemokine receptor 1 (CXCR1) protein, a member of the G-protein-coupled receptor family. CXCR1 is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system.
Cat. No.: HY-139874
CAS No.: 2647464-92-2
Target:
Research Areas:
CXCR2 antagonist 3 (compound 11h) is a potent antagonist of CXC chemokine receptor 2 (CXCR2). CXCR2 antagonist 3 demonstrates double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch. CXCR2 antagonist 3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3 + T lymphocytes into the Pan02 tumor tissues .
Cat. No.: HY-169859
CAS No.: 3035217-40-1
Research Areas:
EP4 receptor antagonist 7 (Compound 14) is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4 with an IC50 value of 1.1 nM. EP4 receptor antagonist 7 inhibits PGE2-induced β-arrestin recruitment in HEK293 cells with an IC50 value of 0.9 nM. EP4 receptor antagonist 7 decreases PGE2-induced expression of mRNA encoding IL-4, macrophage mannose receptor 1 (Mrc1), chitinase-like protein 3 (Chil3), chemokine (C-X-C) motif ligand 1 (Cxcl1), triggering receptor expressed on myeloid cells 2 (Trem2), and arginase-1 (Arg1), in RAW 264.7 macrophages. EP4 receptor antagonist 7 combined with an anti-PD-1 antibody inhibits tumor growth and increases infiltration of CD 8+ T cells into tumors in a CT26 murine colon cancer model .
Cat. No.: HY-125567
CAS No.: 138559-60-1
Target:
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
