577782-52-6
Chemical Structure
CTCE-0214
- CAS No.: 577782-52-6
- Formula:C170H254N44O40
- Molecular Weight:3554.11
SMILES: O=C(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]2N(CCC2)C([C@@H](N)CCCCN)=O)=O)C(C)C)=O)CO)=O)CC(C)C)=O)CO)=O)CC3=CC=C(C=C3)O)=O)CCCNC(N)=N)=O)C)=O)=O)CC4=CC=CC=C4)=O)CCCNC(N)=N)=O)CC5=CC=CC=C5)=O)CC6=CC=CC=C6)=O)=O)=O)=O)=O)CC(C)C)=O)CCCCN7)=O)CC8=CNC9=C8C=CC=C9)=O)[C@H](CC)C)=O)CCC(N)=O)=O)CCC7=O)=O)CC%10=CC=C(C=C%10)O)=O)CC(C)C)=O)CCC(O)=O)=O)CCCCN)=O)C)=O)CC(C)C)=O)C(N)=O)N
Biological Activity: CTCE-0214 is a chemokine CXC receptor 4 (CXCR4) agonist, SDF-1α (stromal cell-derived factor-1α) peptide analog. CTCE-0214 shows anti-inflammatory activity, and can be used in inflammation sepsis and systemic inflammatory syndromes research[1][2][3].
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CTCE-0214 | 99.96% | CTCE-0214 is a chemokine CXC receptor 4 (CXCR4) agonist, SDF-1α (stromal cell-derived factor-1α) peptide analog. CTCE-0214 shows anti-inflammatory activity, and can be used in inflammation sepsis and systemic inflammatory syndromes research. | ||||||||||||||||||||
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- [1]. Fan H, et al. Beneficial effect of a CXCR4 agonist in murine models of systemic inflammation. Inflammation. 2012 Feb;35(1):130-7. [Content Brief]
- [2]. Faber A, et al. The many facets of SDF-1alpha, CXCR4 agonists and antagonists on hematopoietic progenitor cells. J Biomed Biotechnol. 2007;2007(3):26065. [Content Brief]
- [3]. Li K, et al. Small peptide analogue of SDF-1alpha supports survival of cord blood CD34+ cells in synergy with other cytokines and enhances their ex vivo expansion and engraftment into nonobese diabetic/severe combined immunodeficient mice. Stem Cells. 2006 Jan;24(1):55-64. [Content Brief]
Keywords